Does having a BCP with more progestin mean MORE or LESS androgen (if the pill has low androgen potency).
For example, ortho tri cyclen and ortho cyclen contain norgestimate, a progestin with low androgenicity. However, would ortho cyclen's constant level of higher progestin REDUCE androgen or would more progestin automatically mean more androgen? Trying to decide if i should go from OTC lo to regular ortho tri cyclen or ortho cyclen.
It is not that simple, unfortunately.
Progesterone is both a hormonal precursor and a hormonal regulator.
It can downregulate testosterone and estrogen.
It can also convert into testosterone and estrogen.
That is for natural progesterone. I honestly don't know if synthetic progestin is capable of the same downregulation / conversion as natural progesterone.
Anecdotally, you can look at something like Ortho Tri Cyclen Lo, which has a low androgenic progestin, but has less estrogen. In other words, a higher progestin level compared to estrogen. Acne sufferers do not typically fare well on this medication, even though the progestin is not very androgenic.
Ortho Cyclen is the best of those three for acne, in my opinion. It has a good dose of estrogen and is monophasic.
Edited by Green Gables, 25 October 2013 - 03:49 PM.