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So, there seems to be pretty strong anecdotal evidence regarding accutane's effects on long bone growth. I took accutane when I was about 13, and I'm about an inch shorter than my potential height. However, I've grown about three inches since so I don't believe I suffered from epiphyseal closure which stops long bone growth altogether. Do you think that most cases of stunted growth in accutane users are to accutane's effects on the IGF-1 axis rather than epiphyseal closure? The only publicly available study on the matter concludes that accutane "lowers IGF-1 levels significantly", and higher IGF-1 levels have been associated with increased bone growth.

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Accutane is toxic. Im sure there is a very technical reason as to why it causes stunted growth but the simplest explaination is, its toxic to the body. Look what it does to a fetus...

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Accutane does cause ephyiseal clousre in some! It can be determined by a xray. Also, your claim could in fact be very true for some also. Retnoids, Accutane has a profound effect on bones in many diffrent ways, some have a overgrowth and develop spurs etc..some have bone loss, spine changes and soo on.


The secret of health for both mind & body

is not to mourn for the past, not to worry about the future, or not anticipate troubles, but to live the present moment wisely and earnestly.

The Buddha


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hi everyone, i started accutane 2 days ago. I didn't know about the possiblity of growth arrest. So i stopped using it. I only took 4 pills. I am wondering if that could do anything to my growth. Sorry for bad english. English is my second language. Thanks for answers

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