I took accutane about 24 months ago after trying everything else. My acne was never severe but it was painful, stubborn and looked bad. The first time I took it I was completely clear in 3 months, I had the usual symptoms of severe dryness and although my skin was clear the dryness still meant my skin was very red/reactive and didn't look healthy until about 2 months after I stopped. I also noticed my head was fuzzy for a while and my cognition definitely deteriorated but not so much that I felt depressed. I was on 30mg for 6 months, and because I had a history of anxiety/panic the derm didn't want to increase my dose, I feel that had he done so my acne wouldn't have returned, but I can't say for sure.
Sometime mid last year my acne came back in phases, I tried to manage it with diet, exercise, good skin care regimen and controlling stress, but nothing worked so I started my second course of Accutane 3 weeks ago.and so far as I hoped my skin is almost clear.
I am taking 40mg this time but I have put on a bit of weight since the 1st course so it probably has the same effect, I have the same sides and the fuzzy head, nightmares and pooer cognitive performance, and I have been more stressed than normal but nothing I am unable to handle.
I really hope this time the acne doesn't return, I feel that when my derm sees me in a months time he will see my skin is very clear and won't increase the dose which I am not sure what to make of, if he increases it then maybe my acne will never return but I could have worse side effects, if he doesn't increase then it may only clear up for a year or so, this would really bother me as I'd rather put it worse side effects than to have to endure accutane for another 6 months on a 3rd course.