So, I never had acne as a teen. As an adult, I would get randon breakouts, mainly around my period. I went to my derm and she gave me Epiduo, which worked great. My breakouts were minimal and I was pretty happy. The one thing that I did not like was that it seemed to really dry me out. I started reading all this stuff about how BP is associated with premature aging of the skin and that it could cause damage, so I asked my derm to switch me to tretinoin. I began using the .05% cream and my skin looked healthy, even though I would get a pimple here and there, it seemed to be fine. The next time I went, I asked if I should maybe increase the dose since I didn't have any issues on the lowest dose, I figured that the .1% would give me even better results. Boy was I wrong!! My skin freaked out on this and I am broken out on my chin and on my lower right cheek. The odd thing is that I never break out on my left side or on my forehead...it's has always been isolated to one area when I do breakout. I called my derm and she called in an Rx for doxy and she switched me back to the .05 % tretinoin. Is it unusual to only breakout on one side of your face? Is Tretinoin known for causing a major breakout? I have been treating my right lower cheek and my chin with BP and I have been using Tretinoin 1% on the rest of my face..I do not mix the treatments because I know that BP will render the Tret useless, but it;s just SO odd to me that the other half of my face is fine with it and only a very specific area of my face will break out. I'm not sure if it's hormonal or if it's because I sleep on my right side, but I am so frustrated and I don't even want to go out until this clears up:( Help!