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Is Acne An Auto Immune Disease?


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#1 foreverbold

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Posted 27 March 2013 - 07:58 PM

I'm talking about longstanding inflammatory acne that doesn't go away after puberty and gets carried into adulthood. Would you consider it an autoimmune skin condition like Eczema or a hormonal disease? 


Morning skin care routine:
 
- Cetaphil gentle cleanser
- Panoxyl B.P
- Cetaphil daily moisturizer (applied generously)
 
 
Night time skin care routine:
 
- Cetaphil gentle cleanser
- Panoxyl B.P
- Cetaphil daily moisturizer (applied generously)

#2 Quetzlcoatl

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Posted 27 March 2013 - 11:12 PM

hmm yeah it sure could be. I mean, it's mediated by the immune system. And known autoimmunes can have skin rashes as a symptom



#3 whoartthou1

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Posted 28 March 2013 - 12:03 AM

if it indeed is an auto immune disease, how would one go about curing it??



#4 foreverbold

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Posted 28 March 2013 - 01:21 AM

if it indeed is an auto immune disease, how would one go about curing it??

 

Most autoimmune disease have no cure. There are drugs like prednisone to put them in remission and lessen inflammation.

 

I have heard of doctors giving some people with extremely severe cystic acne prednisone to bring down inflammation, there's even threads here on acne.org talking about this.


Edited by foreverbold, 28 March 2013 - 01:23 AM.

Morning skin care routine:
 
- Cetaphil gentle cleanser
- Panoxyl B.P
- Cetaphil daily moisturizer (applied generously)
 
 
Night time skin care routine:
 
- Cetaphil gentle cleanser
- Panoxyl B.P
- Cetaphil daily moisturizer (applied generously)

#5 whoartthou1

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Posted 28 March 2013 - 01:41 AM

what about accutane??



#6 alternativista

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Posted 28 March 2013 - 07:12 AM

It is inflammation related.
Status: Clear after 30 years. Wow, I guess it's been 6 years, now.

[ Story: Severe Acne since I was 10. 10+ years of Dermatologists, Antibiotics, topicals and ACCUTANE did nothing. Discovered oranges triggered the worst of my cystic acne = about 70% improvement. Tried some nutrient supplements like B-complex with zinc and C, saw palmetto and a BHA like the aspirin mask = more improvement, a lot less oily. Then, Diet changes = Clear.

Regimen: Anti-inflammatory, nutrient dense, blood sugar stabilizing diet and supplements (for hormones, inflammation, aging, health). No soap or other cleanser except for hand washing! Water only or Oil cleanse. Aloe Vera mixed with niacinimide and a high linoleic acid oil for moisturizer and reduce pigmentation.

Diet effects acne in so many ways: hormone balance, inflammation, Insulin levels, digestion, allergies and intolerances, liver function, adrenal function, SHBG levels, sebum quality, cell function and turnover, nutrient deficiencies, body fat, etc. Basic advice: Eat, sleep, supplement and exercise like you are a diabetic. And eat real food!

For more information, see my Good Things for Acne thread *Moderator edit - Please refer to the board rules (see “Advertising/soliciting”, “Linking” and “Signatures”)*

When you eat stuff, Stuff Happens!

#7 Quetzlcoatl

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Posted 28 March 2013 - 11:35 PM

Hm you could try taking colostrum to modulate the immune system. You would probably breakout initially because of the IGF but after maybe 2-3 weeks you might start to improve. Colostrum has a lot of IgG antibodies and so-called transfer factors (and a bunch of other useful stuff). It could be a stretch, but you might be able to retrain your immune system to a degree. The reason it takes 2-3 weeks is because that's how long it takes for immunity to build (basically you need to wait for your lymphocytes to respond and proliferate)

 

Out of curiosity, did you get breast milk or formula, and if the former, how long? You don't have to answer that if it's too personal



#8 foreverbold

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Posted 29 March 2013 - 12:26 AM

Hm you could try taking colostrum to modulate the immune system. You would probably breakout initially because of the IGF but after maybe 2-3 weeks you might start to improve. Colostrum has a lot of IgG antibodies and so-called transfer factors (and a bunch of other useful stuff). It could be a stretch, but you might be able to retrain your immune system to a degree. The reason it takes 2-3 weeks is because that's how long it takes for immunity to build (basically you need to wait for your lymphocytes to respond and proliferate)

 

Out of curiosity, did you get breast milk or formula, and if the former, how long? You don't have to answer that if it's too personal

 

 

I was given formula as a baby, not breast milk (my mother couldn't breast feed due to the medication she had to take at the time).

 

Besides acne I've also had problems with keratosis pilaris (though it's really mild now) and Psoriasis on my scalp and neck that comes and goes. And I have had two severe outbreaks of a skin condition called Pityriasis lichenoides (once when I was fifteen on my stomach and legs and then at 19 all over my body (mostly the trunk and arms).

 

Though I hardly ever get sick with a cold or Flu so my immune system isn't "boken" entirely either.


Morning skin care routine:
 
- Cetaphil gentle cleanser
- Panoxyl B.P
- Cetaphil daily moisturizer (applied generously)
 
 
Night time skin care routine:
 
- Cetaphil gentle cleanser
- Panoxyl B.P
- Cetaphil daily moisturizer (applied generously)

#9 whoartthou1

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Posted 29 March 2013 - 02:15 AM

Hm you could try taking colostrum to modulate the immune system. You would probably breakout initially because of the IGF but after maybe 2-3 weeks you might start to improve. Colostrum has a lot of IgG antibodies and so-called transfer factors (and a bunch of other useful stuff). It could be a stretch, but you might be able to retrain your immune system to a degree. The reason it takes 2-3 weeks is because that's how long it takes for immunity to build (basically you need to wait for your lymphocytes to respond and proliferate)

 

Out of curiosity, did you get breast milk or formula, and if the former, how long? You don't have to answer that if it's too personal

 

 

I was given formula as a baby, not breast milk (my mother couldn't breast feed due to the medication she had to take at the time).

 

Besides acne I've also had problems with keratosis pilaris (though it's really mild now) and Psoriasis on my scalp and neck that comes and goes. And I have had two severe outbreaks of a skin condition called Pityriasis lichenoides (once when I was fifteen on my stomach and legs and then at 19 all over my body (mostly the trunk and arms).

 

Though I hardly ever get sick with a cold or Flu so my immune system isn't "boken" entirely either.

 

It is funny you say the "sick/cold" thing because I rarely get sick, yet I struggle with skin problems (acne all over body, seborrheic dermatitis all over face and body).

 

I was breast-fed for like 3 months and formula fed the rest. I believe the key is that we were formula fed. It screwed us up for life.



#10 Quetzlcoatl

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Posted 29 March 2013 - 08:43 AM

So breast milk/colostrum has tons of immune-related functions. Not getting it like whoartthou said could really be key. My mother was not breast fed, and all 3 of her children suffered from acne, even though she did breast-feed all of us (although, there is an n=3 correlation between length of breast feeding and acne severity)

 

Unfortunately, not getting sick could be a sign of an incomplete immune system. I'm not talking about immunocompromised, where you simply lack the right cells, but about a misguided response to antigen. Psoriasis, for example, is basically an autoimmune disease. The immune system is there to make you sick, so you are aware that something in your body is wrong, and you can give it time to recover. If it does not make you sick while there is something wrong, it is not combating the problem, probably because it doesn't recognize the problem to be a problem. Instead, it might recognize something else to be a problem for no reason, and then give you psoriasis, while letting the real problem continue. Sometimes there doesn't even have to be a real problem, and your immune system will just do whatever the hell it wants



#11 dejaclairevoyant

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Posted 29 March 2013 - 10:12 AM

I was breast fed and have one of the most difficult to cure cases ever. So I really do not think it's that.


Current Skin-Care Regimen (A work in progress):

 

Morning:

Gentle wash with DKR cleanser

Benzoyl Peroxide 2.5% (Following Dan's Regimen)

DKR Lotion + A squirt of Argan or Grapeseed oil (The  lotion alone wasn't hydrating enough)

Skin 79 Korean BB Cream (excellent stuff)

 

Evening:

Gentle Wash with DKR Cleanser

Benzoyl Peroxide 2.5% (Following Dan's Regimen)

DKR Lotion + A squirt of Argan or Grapeseed oil

 


#12 Quetzlcoatl

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Posted 30 March 2013 - 12:37 AM

Different things, different people. If one ancestor wasn't breast fed, it could have epigenetic and antibody effects for a few generations. But when we start to rule things out like diet and hormones, its good to look at the basics