Are you changing your regimen on your own or at the advice of a physician? I wouldn't mess with it without a doctor's consent. To cure cystic acne along my chin, I've been taking 50 mg of spiro in conjunction with topical treatments and washes for like 9 or 10 months. I cleared up almost completely around my 6th or 7th month. My derm allowed me to cut down to 25 mg and I started breaking out around my chin and mouth a week or two after the drop. On her advice, I bumped the daily dosage back up to 50 mg for a month and have been slowly clearing back up. I just got engaged (so I'm visiting with a lot of friends and family, will be taking pictures soon), and am terrified of cutting back down when the month is over. I guess the spiro had more of an effect on my acne than I thought; I had assumed the topicals were doing all of the work.
My advice to you would be to 1) consult your prescribing physician! And that 2) sometimes less is more. I've heard people have good results with spiro at the 25mg - 50mg range. It may take awhile, (it took me 6-7 months) but you will clear up. Good luck to you!
Okay, I'll def call my physician. I would like less to be more, but I'm scared my body isn't responding the the lesser amount "50mg" as its used to...
And topicals actually never help me haha. It's actually been the spiro all this time.
I'm no physician, so don't quote me on this, but since spiro controls testosterone levels in the body, I don't think it's a matter of building up a tolerance and needing to up your dosage to get a better result. I think it's more about finding the right dosage that puts your hormones in harmony. Everyone reacts differently to hormones, so what's best for you could wreck havoc on someone else. But I could be wrong!
I should also mention I went on birth control to help with the cystic acne. I take loloestrin fe, but it had no effect on my acne. I'm very sensitive to hormones, and this is a very low dose pill. All of the generic birth control brands that I had tried previously gave me horrible pain in my breasts or had an adverse effect on my mood.
What topicals have you tried? I'm using Aczone in the morning and Ziana in the evenings. The Ziana is supposed to help with my redness and possible scarring. In the beginning, I was using Finacea in the morning with Aczone but my derm cut it out of my regimen once I started seeing dramatic results. The Finacea reduced inflammation. I use Sumaden for wash. My moisturizer is aveeno but my derm does not recommend it (she thinks it's too oily), but I love it so much and can't give it up Everything else she's given me has left my skin feeling so dry. So I just try to use less of the Aveeno.