Jump to content

Photo

Accutane 120 Mg!

accutane 120 mg large dose returing acne? month 5 month 6 month 4

This topic has been archived. This means that you cannot reply to this topic.
21 replies to this topic

#1 omar1234

omar1234

    New Member

  • Members
  • Posts & Likes
    Posts: 3
    Likes: 0
About Me
  • Joined: 16-February 13

Posted 16 February 2013 - 11:09 PM

Okay so I've been on accutane for 5 and a half months. The first month i was on 40 mg everyday and by the end was starting to clear up, for the next two months my doctor bumped me up to 60 mg , and by month 4 i was on 80 mg, for months 4 and half of five i was very clear and was stoked on my accutane and how it was working, however by the end of month 5 i went on an overseas trip for a week and unfortunately missed out on two weeks of dosage, i didn't breakout too bad but my moderate acne had came back :( so at my next trip to the derm she decided to put me on 120 mg everyday,  and im positive that , that is an intense dosage especially since im only 5'9 and 140 pounds! im pretty sure that's twice the maximum dosage for me! but my acne has cleared up again despite a small breakout which i think was a result of the upped dosage, so my biggest concern here is whether or not the acne will come back as soon as i finish my 6th month! i mean i didn't put up with hell and have been a fuckin vampire for the last 5 months and conjured up some depressing thoughts just for my acne to come back as soon as i get off it!  please can someone give me their opinions on whether my acne will return? or what factors contribute to the possibility of it coming back? I'm 15 , if that's a contributing factor I'm still  unsure.



#2 BMarieWantsNoAcne

BMarieWantsNoAcne

    Member

  • Veteran Members
  • Posts & Likes
    Posts: 288
    Likes: 42
About Me
  • Joined: 04-November 12

Posted 16 February 2013 - 11:26 PM

I don't know, but this is a really strong drug and that is an extremely high dose. I'fe never heard of such a high dose. I don't recommend it at all.

#3 omar1234

omar1234

    New Member

  • Members
  • Posts & Likes
    Posts: 3
    Likes: 0
About Me
  • Joined: 16-February 13

Posted 18 February 2013 - 03:38 PM

well i mean i'm half way through the last month taking 120 mg and i haven't experienced any unusual side effects and its my last month so i think i should be fine! just still curious on if this high dose will cause my acne to come back  



#4 Rorius

Rorius

    Member

  • Veteran Members
  • Posts & Likes
    Posts: 137
    Likes: 13
About Me
  • Joined: 22-January 13

Posted 18 February 2013 - 07:01 PM

Higher doses have lower remission rates, so your acne is actually much less likely to come back.

 

Don't worry about the high dose as long as your blood tests come back ok, and you can deal with the side effects.



#5 sallysa

sallysa

    Junior Member

  • Members
  • Posts & Likes
    Posts: 35
    Likes: 1
About Me
  • Joined: 26-April 11

Achievements

     

Posted 19 February 2013 - 12:44 PM

yes if it were me I would make sure to watch my blood work like a hawk.  I personally wouldn't be comfortable with a dose that high.  But I wasn't comfortable with 80 mg per day either.  I'm currently on 60.  But I also think you're so young and younger bodies seem to be more resilient and able to deal with more. 

 

Good luck.



#6 Livetoregret

Livetoregret

    Member

  • Veteran Members
  • Posts & Likes
    Posts: 295
    Gallery Images: 14
    Likes: 51
About Me
  • Joined: 22-October 12

Posted 20 February 2013 - 03:48 PM

120 mg is straight up insane.

 

Get a new doctor and report your current doctor to the medical board - there is no safe way to be taking a dosage that high and there is absolutely no need for it. doctors are completley irresponsible and are NOT looking out for your best interests regarding your long term health.
Do some research on how low dose treatment like 20 mg's twice a week has the exact same result as a typical 40 mg per day dosage.

 

Also - cumulative dosage means nothing. If you have a hormonal imbalance your acne will return anyway.



#7 Rorius

Rorius

    Member

  • Veteran Members
  • Posts & Likes
    Posts: 137
    Likes: 13
About Me
  • Joined: 22-January 13

Posted 20 February 2013 - 06:11 PM

Amazing the amount of people on these boards that know better than dermatologists!



#8 BMarieWantsNoAcne

BMarieWantsNoAcne

    Member

  • Veteran Members
  • Posts & Likes
    Posts: 288
    Likes: 42
About Me
  • Joined: 04-November 12

Posted 21 February 2013 - 01:12 PM

That's true Rorius. I wouldn't go on a dose that high... even 80 is pushing it for me, but I'm taking that. If he's fine with it then go ahead...

Edited by BMarieWantsNoAcne, 21 February 2013 - 01:13 PM.


#9 Rorius

Rorius

    Member

  • Veteran Members
  • Posts & Likes
    Posts: 137
    Likes: 13
About Me
  • Joined: 22-January 13

Posted 22 February 2013 - 10:20 AM

The biggest problem with taking a high dose are the severity of the usual side effects of Isotretinoin- dry skin/lips/eyes, eczema, nosebleeds etc.

 

The blood tests are actually there because a minority of patients are hypersensitive to the drug which is obviously dangerous- but for most, the tests return only slight changes of liver enzymes & triglyceride levels, and a toxic dose for most people is much higher than would ever be prescribed.

 

That's from my Derm anyway.



#10 nomo

nomo

    Junior Member

  • Members
  • Posts & Likes
    Posts: 68
    Likes: 6
About Me
  • Joined: 30-October 10

Posted 01 March 2013 - 10:11 PM

Isn't it weight based??  I am prescribed 1mg/kg/day, but am overweight.  So my dose is a total of 90mg/day.   Today is my first day taking it, but I am confused by the "that is way too much" chatter.  Can someone clarify, please?  I am a nurse and drugs are frequently titrated per weight.  Most literature that I have read regarding accutane states that 1mg/kg/day has the most positive results and the least risk for the acne to return.  Anyone have some literature to present that states that it should not be weight based dosed or includes high limit doses??  Thanks.  I am now concerned.



#11 taiersi

taiersi

    New Member

  • Members
  • Posts & Likes
    Posts: 6
    Likes: 0
About Me
  • Joined: 25-March 13

Posted 25 March 2013 - 07:37 AM

Okay so I've been on accutane for 5 and a half months. The first month i was on 40 mg everyday and by the end was starting to clear up, for the next two months my doctor bumped me up to 60 mg , and by month 4 i was on 80 mg, for months 4 and half of five i was very clear and was stoked on my accutane and how it was working, however by the end of month 5 i went on an overseas trip for a week and unfortunately missed out on two weeks of dosage, i didn't breakout too bad but my moderate acne had came back sad.png so at my next trip to the derm she decided to put me on 120 mg everyday,  and im positive that , that is an intense dosage especially since im only 5'9 and 140 pounds! im pretty sure that's twice the maximum dosage for me! but my acne has cleared up again despite a small breakout which i think was a result of the upped dosage, so my biggest concern here is whether or not the acne will come back as soon as i finish my 6th month! i mean i didn't put up with hell and have been a fuckin vampire for the last 5 months and conjured up some depressing thoughts just for my acne to come back as soon as i get off it!  please can someone give me their opinions on whether my acne will return? or what factors contribute to the possibility of it coming back? I'm 15 , if that's a contributing factor I'm still  unsure.

I never heard such a high dosage you will take( 120mg/day),,,,,,,,i am 55kg and i only take 20mg-30mg everyday,,,,i think it arounds the safe line-0.5mg/kg/day,,,,,,but 120mg for you that is 2mg/kg!



#12 LillyRose7

LillyRose7

    Member

  • Veteran Members
  • Posts & Likes
    Posts: 207
    Likes: 22
About Me
  • Joined: 05-December 11

Posted 25 March 2013 - 08:11 AM

thats really high, 120mg probably the highest i have ever heard. I've heard of the bad stuff happening around 80mg or so. I was told i would clear on 20mg, and maybe MAX 30mg but i am 5'2 and about 120ish pounds or 55kg but, be careful. You might not suffer now but maybe 1,2, 3 months down the line or maybe even 1 year.



#13 ughhhhh

ughhhhh

    Member

  • Veteran Members
  • Posts & Likes
    Posts: 238
    Likes: 39
About Me
  • Joined: 15-September 12

Posted 25 March 2013 - 10:19 AM

Dosages that high are reserved for people who have severe nodulocystic acne, conglobata, severe truncal acne. My derm said I might have to build up to that dose (but doubts it), and I'm quite scared of it but so far at 4 months, I have seen literally no change in the nodules and cysts on my face. Low dosages (.5mg/kg) work for regular acne, which is most people.



#14 oli girl

oli girl

    Veteran Member

  • Veteran Members
  • Posts & Likes
    Posts: 1,679
    Likes: 108
About Me
  • Joined: 16-March 09

Posted 25 March 2013 - 01:12 PM

Ohh! I was given 100mg my last month 5 yrs ago for some cysts and did the subtle side effects kick in 2 months after course full blown with devastating effects! Was 120pds!

By the way if they are sebaceous cysts accutane won't work! Mine surgically removed

#15 IDK111

IDK111

    Member

  • Veteran Members
  • Posts & Likes
    Posts: 130
    Likes: 28
About Me
  • Joined: 25-March 13

Posted 25 March 2013 - 07:01 PM

WHAT?!

 

I agree that you might see the affects later, some of which could be irreversible.

 

I am scared FOR YOU.



#16 oli girl

oli girl

    Veteran Member

  • Veteran Members
  • Posts & Likes
    Posts: 1,679
    Likes: 108
About Me
  • Joined: 16-March 09

Posted 26 March 2013 - 09:42 PM

Isn't it weight based??  I am prescribed 1mg/kg/day, but am overweight.  So my dose is a total of 90mg/day.   Today is my first day taking it, but I am confused by the "that is way too much" chatter.  Can someone clarify, please?  I am a nurse and drugs are frequently titrated per weight.  Most literature that I have read regarding accutane states that 1mg/kg/day has the most positive results and the least risk for the acne to return.  Anyone have some literature to present that states that it should not be weight based dosed or includes high limit doses??  Thanks.  I am now concerned.

Doesn't matter about dosage when it comes to acne returning..... do a search on the board you'll find many who's acne returned and if yours is due to hormones, well hormones aren't cured by accutane, in fact in some can make hormonal problems worse. As for be concerned I'd be more concerned about the side effects listed. People have had issues with as little as 20mg! Good Luck!



#17 nomo

nomo

    Junior Member

  • Members
  • Posts & Likes
    Posts: 68
    Likes: 6
About Me
  • Joined: 30-October 10

Posted 26 March 2013 - 10:02 PM

Okay so I've been on accutane for 5 and a half months. The first month i was on 40 mg everyday and by the end was starting to clear up, for the next two months my doctor bumped me up to 60 mg , and by month 4 i was on 80 mg, for months 4 and half of five i was very clear and was stoked on my accutane and how it was working, however by the end of month 5 i went on an overseas trip for a week and unfortunately missed out on two weeks of dosage, i didn't breakout too bad but my moderate acne had came back sad.png so at my next trip to the derm she decided to put me on 120 mg everyday,  and im positive that , that is an intense dosage especially since im only 5'9 and 140 pounds! im pretty sure that's twice the maximum dosage for me! but my acne has cleared up again despite a small breakout which i think was a result of the upped dosage, so my biggest concern here is whether or not the acne will come back as soon as i finish my 6th month! i mean i didn't put up with hell and have been a fuckin vampire for the last 5 months and conjured up some depressing thoughts just for my acne to come back as soon as i get off it!  please can someone give me their opinions on whether my acne will return? or what factors contribute to the possibility of it coming back? I'm 15 , if that's a contributing factor I'm still  unsure.

This is standard practice.  My derm said the exact same thing today.  Standard is 1mg/kg/day.  If someone has a return after their first course, than it is standard to administer 1.5-2mg/kg/day. 

 

I feel it is important to stay in touch with research and evidenced based practice.  This forum is extremely helpful, however, it is just a forum with anonymous posters.  You should trust the expert, your dermatologist, and if you don't, you should get a new one.



Isn't it weight based??  I am prescribed 1mg/kg/day, but am overweight.  So my dose is a total of 90mg/day.   Today is my first day taking it, but I am confused by the "that is way too much" chatter.  Can someone clarify, please?  I am a nurse and drugs are frequently titrated per weight.  Most literature that I have read regarding accutane states that 1mg/kg/day has the most positive results and the least risk for the acne to return.  Anyone have some literature to present that states that it should not be weight based dosed or includes high limit doses??  Thanks.  I am now concerned.

Doesn't matter about dosage when it comes to acne returning..... do a search on the board you'll find many who's acne returned and if yours is due to hormones, well hormones aren't cured by accutane, in fact in some can make hormonal problems worse. As for be concerned I'd be more concerned about the side effects listed. People have had issues with as little as 20mg! Good Luck!

Thanks for your insight. However, I was hoping for scholarly literature.  :)



#18 oli girl

oli girl

    Veteran Member

  • Veteran Members
  • Posts & Likes
    Posts: 1,679
    Likes: 108
About Me
  • Joined: 16-March 09

Posted 26 March 2013 - 10:19 PM

Okay so I've been on accutane for 5 and a half months. The first month i was on 40 mg everyday and by the end was starting to clear up, for the next two months my doctor bumped me up to 60 mg , and by month 4 i was on 80 mg, for months 4 and half of five i was very clear and was stoked on my accutane and how it was working, however by the end of month 5 i went on an overseas trip for a week and unfortunately missed out on two weeks of dosage, i didn't breakout too bad but my moderate acne had came back sad.png so at my next trip to the derm she decided to put me on 120 mg everyday,  and im positive that , that is an intense dosage especially since im only 5'9 and 140 pounds! im pretty sure that's twice the maximum dosage for me! but my acne has cleared up again despite a small breakout which i think was a result of the upped dosage, so my biggest concern here is whether or not the acne will come back as soon as i finish my 6th month! i mean i didn't put up with hell and have been a fuckin vampire for the last 5 months and conjured up some depressing thoughts just for my acne to come back as soon as i get off it!  please can someone give me their opinions on whether my acne will return? or what factors contribute to the possibility of it coming back? I'm 15 , if that's a contributing factor I'm still  unsure.

This is standard practice.  My derm said the exact same thing today.  Standard is 1mg/kg/day.  If someone has a return after their first course, than it is standard to administer 1.5-2mg/kg/day. 

 

I feel it is important to stay in touch with research and evidenced based practice.  This forum is extremely helpful, however, it is just a forum with anonymous posters.  You should trust the expert, your dermatologist, and if you don't, you should get a new one.



Isn't it weight based??  I am prescribed 1mg/kg/day, but am overweight.  So my dose is a total of 90mg/day.   Today is my first day taking it, but I am confused by the "that is way too much" chatter.  Can someone clarify, please?  I am a nurse and drugs are frequently titrated per weight.  Most literature that I have read regarding accutane states that 1mg/kg/day has the most positive results and the least risk for the acne to return.  Anyone have some literature to present that states that it should not be weight based dosed or includes high limit doses??  Thanks.  I am now concerned.

Doesn't matter about dosage when it comes to acne returning..... do a search on the board you'll find many who's acne returned and if yours is due to hormones, well hormones aren't cured by accutane, in fact in some can make hormonal problems worse. As for be concerned I'd be more concerned about the side effects listed. People have had issues with as little as 20mg! Good Luck!

Thanks for your insight. However, I was hoping for scholarly literature.  smile.png

 

Acutally you can find scholarly studies online regarding low dose treatment vs high dose! U.S. are notroius for high doses and you find people on here who cleared up on low doses without severe long term side effects :)  I could look up from my husbands acess who is a phyisican (should of been smart and used that before I took such a harsh drug I wouldn't be where I am today) but it won't be for  a few days :) However, they are out there! Good Luck If accutane doesn't work the first time, don't do a second course unless you have the severe acne congblata etc.. that it is acutally designed for and that is documented in you rx information!

 

Good Luck



#19 oli girl

oli girl

    Veteran Member

  • Veteran Members
  • Posts & Likes
    Posts: 1,679
    Likes: 108
About Me
  • Joined: 16-March 09

Posted 26 March 2013 - 10:38 PM

I guess I leave this thread with this " We simply assume, that doctors have a personal responsiblity. They are specialists, who have the information either in thier head or they know where to find it" Andres Schneider, Swissmedic

 

You have to be an advocate for your own health, If you get a permanent damage/side effect, you have to live with it!, It is way over prescribe and really only for severe acne congblata and servere skin diseases. There is no scholarly studies, it comes straight from Roche and the inventor themselves. 

 Like I said my derm gave me a 100mg for 1 month weighing only 120pds and telling me that accutane only causes dry skin and not to take to much thought in the rx info on side effects...but instead it killed my pancreas and well now I have hormonal acne!

 

You can find on this board and others of people taking it 3 times and thier acne comes back, if any doctor tells accutane is a cure all for acne then find a new derm as many will disagree with that!



#20 AuguriesofInnocence

AuguriesofInnocence

    Member

  • Veteran Members
  • Posts & Likes
    Posts: 431
    Gallery Images: 3
    Likes: 84
About Me
  • Joined: 03-April 12

Posted 19 April 2013 - 03:46 AM

120 mg is straight up insane.

 

Get a new doctor and report your current doctor to the medical board - there is no safe way to be taking a dosage that high and there is absolutely no need for it. doctors are completley irresponsible and are NOT looking out for your best interests regarding your long term health.
Do some research on how low dose treatment like 20 mg's twice a week has the exact same result as a typical 40 mg per day dosage.

 

Also - cumulative dosage means nothing. If you have a hormonal imbalance your acne will return anyway.

hi, I completely agree with both livetoregret and oli girl...not only is the dosage youre taking extremely high, even the lowest possible dose (10 mg) was toxic for me. I took accutane 1 month and I had horrible cracked lips, nosebleeds and depression so severe I was suicidal.

Why this is on the market yet is a mystery to us all.

My advise is just STOP, Im not going to lie, you may have done some damage already so why keep it up? My husband took accutane when he was 17, the 'standard" dose, not only did he get acne back a few years later, he also got IBS, chronic dry eye and possibly arthritis. He suggested I NOT take accutane but I did, and he and my son nearly lost me. I should have listened. My mother had acne most of her life, but back in the 70s they didnt know how to treat it well--she just piled on heavy make-up and now has indented scarring. She never realized the cause, which she passed down to mee, either too much DHT or being very sensative to the normal amount.

Acne IS hormonal at its cause. The only thing which cleared my acne after 20 effing years was pretty simple: yaz birth control. Saw palmetto and spearmint also lower the real cause, DHT.

People have taken accutane 2, 3, 4 times, why? Because the acne comes back. Dont kill your health for a year or possibly two of clear skin, only to be crushed when your oil returns.

Just my input.



Higher doses have lower remission rates, so your acne is actually much less likely to come back.

 

Don't worry about the high dose as long as your blood tests come back ok, and you can deal with the side effects.

I hate to rain on your parade, but a) most people's acne returns at some point within 3-5 years no matter what the dosage, and b) sure your blood tests may be fine (mine were) but that doesnt mean you wont have to deal with terrible possible side effects 5,10 or 15 years down the line. Plus acne. Id stop if I were you, but its your life. If I sound cynical, forgive me, I took 10 mg of accutane for one month and tried to kill myself. I care more about a persons life than the state of their skin.



Why do you assume that some derm cares so much about your well-being? How many drugs are taken off the market every year for killing people? When I was prescribed accutane by my very affable, smiling derm, he assured me that very few people get serious side effects, accutane has an unfairly poor reputation, and Im not the type to get depressed. Exactly one month after taking my first pill, I had a gun pointed at myself because I was extremely depressed from this drug. If I would have died, would he have felt bad? probably for a bit...and then keep on prescribing his patients accutane.

Each one of us is responsible for our own health, we pay doctors and hope they know what the hell they are doing.

Ive  been misdiagnosed with various symptoms 4 times in the past 2 years, by DOCTORS who think they know everything.

Do you know what they call the guy who failed his med boards 5 times, and graduated last in the class?

"Doctor".

Wake up and smell the roses dear, doctors are not God (though a lot of them think they are...)

Amazing the amount of people on these boards that know better than dermatologists!


Edited by AuguriesofInnocence, 19 April 2013 - 03:34 AM.