Does Zinc Increase Or Decrease Dht?

7 posts in this topic

I've read a few posts that said zinc inhibit 5 alpha reductase and reduces DHT, hence it's good for acne.

But then there's this study:

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http://informahealthcare.com/doi/abs/10.3109/01485018109009378

Effect of Zinc Administration on Plasma Testosterone, Dihydrotestosterone, and Sperm Count

"T and DHT rose significantly after oral administration of zinc"

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So it looks like zinc actually increases DHT significantly. Does that mean zinc is something to avoid? Are there any studies that show zinc is actually good for acne?

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If your zinc is on the high side already than zinc increases DHT.

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That study was done on infertile men, so it may not be the best reference. I know zinc increases testosterone in people with low testosterone, and I don't know about DHT. However, zinc is great for acne by reducing inflammation. You shouldn't avoid taking it, and I don't think I've ever seen a post that said zinc made someone break out.

There are plenty of studies. Just google "site:nih.gov" and then whatever keywords you want, and you will find whatever study you want. Here are some: http://www.ncbi.nlm.nih.gov/pubmed/2575335

http://www.ncbi.nlm.nih.gov/pubmed/15908296

http://www.ncbi.nlm.nih.gov/pubmed/139912

http://www.ncbi.nlm.nih.gov/pubmed/20666829


How I Stay Clear:

  • Accutane 5mg/day
  • Probiotics 25 billion organisms/day
  • Cetaphil gentle skin cleanser 2x/day

Low Dose Accutane Log


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Zinc decreases DHT by inhibiting (reducing or stopping) 5 alpha-reductase, an enzyme which is responsible for converting Testosterone (and other hormones as far as I know, but the science on that is not as well-researched from what I've been able to find) into the more potent DHT. DHT = bad testosterone, DHT causes prostate issues in men and also hair loss.

That study is an anomaly. You know how 9 in 10 Dentists recommend Colgate toothpaste? This study is that 10th dentist.

Ok, that's a bad example because Colgate sucks. But you get my point.


After suffering with acne since age 11, finally found my triggers 11 years later.

Clear for almost 1 year & in control of my acne, although due to some hyperpigmentation, I believed I was still breaking out. In fact, I thought I had just cleared up a few months ago, but after realizing my "breakouts" were simply scarring I also realized I was technically clear for much longer than I thought. Rare breakouts only whenever I get lazy with my diet.

The Cure for Acne:

-Avoid the Acne Trifecta: Soy, Gluten, and Dairy like the plague.

-Eat a Low-GI diet and avoid Sugar.

-Eat lots of protein and healthy fats (ANTIBIOTIC FREE/NO HORMONES ADDED/FREE RANGE/HUMANELY SLAUGHTERED)

-Get lots of green vegetables and sunshine.

-Supplement whenever possible. Due to how much we've ruined food in the past 60 years, the amount of nutrients found in food nowadays is lower than it was decades ago.

-Exercise, get sunshine, and avoid stressful situations.

-Don't fear food. Go out & eat. It's not good for the skin, but it's good for the soul.


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As Omnivium mentioned, you can't generalize from one group of people to another. Topically applies zinc has at least some 5-alpha reductase activity. It's also one of the few supplements where there's evidence to show it's effective in acne.
BBC recently reported about a study that showed zinc can keep immune system in check. http://www.bbc.co.uk/news/health-21372790
This could explain why zinc works for acne.

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Zinc helps the body regulate testosterone. So if you are low, as those in this study were, it increases it.


Status: Clear after 30 years. Wow, I guess it's been 6 years, now.

[ Story: Severe Acne since I was 10. 10+ years of Dermatologists, Antibiotics, topicals and ACCUTANE did nothing. Discovered oranges triggered the worst of my cystic acne = about 70% improvement. Tried some nutrient supplements like B-complex with zinc and C, saw palmetto and a BHA like the aspirin mask = more improvement, a lot less oily. Then, Diet changes = Clear.

Regimen: Anti-inflammatory, nutrient dense, blood sugar stabilizing diet and supplements (for hormones, inflammation, aging, health). No soap or other cleanser except for hand washing! Water only or Oil cleanse. Aloe Vera mixed with niacinimide and a high linoleic acid oil for moisturizer and reduce pigmentation.

Diet effects acne in so many ways: hormone balance, inflammation, Insulin levels, digestion, allergies and intolerances, liver function, adrenal function, SHBG levels, sebum quality, cell function and turnover, nutrient deficiencies, body fat, etc. Basic advice: Eat, sleep, supplement and exercise like you are a diabetic. And eat real food!

For more information, see my Good Things for Acne thread *Moderator edit - Please refer to the board rules (see “Advertising/soliciting”, “Linking” and “Signatures”)*

When you eat stuff, Stuff Happens!


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