Not sure about the whole lipid thing to be honest, the jump of: lipid metabolism is broken -> adipose-derived stem cells = cure is not fleshed out in the least. I'll dig further but I'm not convinced.
What I do know:
- It's not an issue that can be treated with basic vitamins / nutrients, I've tried them all, and if this were the case it would be temporary and not lasting years.
- The fact that it's all over the head for most says to be it's not typical MPB
- It seems to be at some level sex hormone related, I took propecia after losing hair for a year straight and within 2 week the loss essentially stopped completely
- My hair loss never came back for 5+ years after taking propecia for a few months or so.
- Others have tried Propecia with little effect, perhaps it only worked for me because it causes hypogonadism
- After the propecia I felt off for years, went to numerous doctors, and eventually discovering I had secondary hypogonadism (very low testosterone), likely caused by the propecia
- I took nolvadex in attempt to restart my natural testosterone production, hair loss started again, I stopped the nolvadex and took the few remaining bits of propecia I had and after 4 month the hair loss stopped again (low testosterone came back as well).
- I was put on Androgel, and the hair loss began again
- I never had receeding temples until I was put on TRT and took too much letrozole that lowered my estrogen to near 0 levels, which to me says B5 hairloss isn't necessarily just DHT derived
- I stopped TRT cold turkey for 8 months, testosterone levels tanked again, but the hair loss continues. I am now back on low dose TRT thinking maybe my estrogen got too low.
My current thoughts on the cause;
- I know it's not thyroid or cortisol based, when the hair loss stopped my levels were fine, when it started again, my levels were fine
- It's not normal MPB in that it doesn't just affect the top of the head. This may point to estrogen issues, perhaps it kills aromatase at the follicle level which explains the loss at the side of the head, as well as accelerating MPB in others. Follicles on the side of the head have higher aromatase and it's one of the reason hair loss doesn't occur there. To test this theory I'm currently using a product called Pantostin from Europe which is a weak estrogen that increases follicle level aromatase.
- It may just up-regulate DHT at the follicle somehow, but if this was true one would expect a huge increase in body hair, which I never got. Perhaps only scalp hair/sebaceous gland areas are affected?
- B5 may somehow messed with gut bacteria such as equol which lowers serum DHT. After taking B5 my stomach started having issues, and I was eventually diagnosed with Celiacs, but this may be unrelated (I don't think it is personally given I had no issues up until the age of 19)
Things I've Tried:
Every vitamin/nutrient under the sun, Pregnanolone cream, DHEA, Progesterone cream, derma-rolling, Laser light therapy, IGF-1 lr3, emu oil, peppermint oil, tea tree oil, ALCAR, NAC, MSM, topical vitamin C, caffeine among lots of other things.
Things I'm going to try:
Pantostin (weak topical estrogen to increase follicle level aromatase),
Scalp IGF-1 lr3 injections
Elmetacin spray topical
Propecia again (last thing to try, I'm already on TRT not all that worried about sides at this point and it worked 10 years ago within a couple weeks)
Edited by jimmyjoners, 05 August 2014 - 05:05 PM.