Jimmyjoners, what are you trying next? Igf-1 lr3 or igf-1 scalp injections? I have never heard of these...
Like Blue09 said, they are peptides used by bodybuilders mostly.
The thinking here, is that DHT down regulates igf-1 at the hair follicle level as one of the ways it kills hair. There was some study that found that for people who Propecia/Finasteride worked for, their hair follicles had up-regulated the expression of igf-1, and for those who didn't respond, igf-1 expression was the same. There are also studies where topical igf-1 was used to increase hair thickness and quantity. So we know igf-1 is good for hair. There was some contention for a long time because some study showed a lot of men with hair loss had either low levels of serum igf-1 OR high levels. Low levels makes sense, high levels however were a bit confusing. Turns out high levels of igf-1 are likely caused by insulin insensitivity (low levels can also be a sign of this), so even if their levels are high the igf-1 isn't binding to it's receptors effectively.
So cool we can all agree igf-1 is good for hair, but now the issue is do you use igf-1 or igf-1 lr3? The lr3 version is a longer chain that allows it to stay in the body for longer (half life of 20 hours or so), where as regular igf-1 is quick metabolized, and acts very locally (bodybuilders will inject it into individual lagging muscles after a work out for localized action). Igf-1 lr3 is used systematically, it has a chance to bind to all sorts of receptors by virtue of being around for so long. But if topical Igf-1 worked, then it makes sense to me that you don't really need the lr3 version, but I can't really see why it would be bad (except for it lower your natural GH release).
I posted before about the hair transplant option but nobody gave any input.
It's really not very expensive nowadays so I'm wondering why nobody else considers this?
My hair is certainly going in classic MPB style, with it receded 1-2 inches. It's been going for around 4-5 years so I'm just glad it isn't too fast, though it might be because my hair used to very thick.
I think it will be a waste of money, all the new hair that starts growing after the op will look stupid when the hair around it falls out, we're losing hair for a reason if everybody starts getting more and more tests done we will probably find the answer, but most people on here are desperate including me and trying pointless stuff which will most likely make the hairloss worse.
Am I the only one who has no pattern to the hair loss? Mine is totally diffuse, not pattern at all.
Edited by jimmyjoners, 24 July 2014 - 03:01 PM.