Posted 02 October 2004 - 03:45 PM
People who take vitamin and antioxidant supplements in the hope they're reducing their risk of gastrointestinal cancer are more likely to die of the disease than those who don't take the supplements, a new study finds.
The research, which reviewed the results of 14 major trials with more than 170,000 participants, found a small but statistically significant increase in gastrointestinal cancer deaths associated with supplements containing beta carotene and vitamins A, C and E.
Four of the trials showed a possible reduction of risk associated with selenium supplements, the report said.
In half the trials, there was a 6 percent increased risk of death from cancers of the esophagus, stomach, pancreas, liver, colon and rectum in persons who took supplements, compared to those who took a placebo, the researchers found.
But certain combinations of supplements seemed to be more dangerous, the researchers said.
A 30 percent higher risk was found for combination supplements containing beta carotene and vitamin A, and a 10 percent risk for supplements combining beta carotene and vitamin E.
"The indication that mortality in supplement-taking patients was higher compared to placebo has to be explored extensively in all randomized trials," said study author Dr. Goran Bjelakovic, a professor of internal medicine at the University of Nis in Serbia and Montenegro.
"The potential protective effect of selenium should be studied in adequate clinical trials," he added.
The study appears in the Oct. 2 issue of The Lancet.
It's not clear why antioxidant supplements might have a harmful effect, Bjelakovic said. One possible explanation is that they might interfere with apoptosis, the process in which the body destroys cells that turn abnormal.
"Someone who takes supplements can suppress apoptosis and thus can influence the growth of different tumors," Bjelakovic said. "But this is only a hypothesis."
Neither the American Cancer Society nor the National Cancer Institute (NCI) recommend vitamin supplements for cancer prevention. A U.S. task force recently reported there is "insufficient evidence" that supplements have any preventive effect. The cancer society recommends getting appropriate amounts of vitamins and minerals by eating a balanced diet.
The NCI is conducting a large-scale trial of selenium and vitamin A for prevention of prostate cancer. The trial was started because two earlier studies suggested a possible protective effect.
In an accompanying editorial in the journal, Drs. David Forman of Leeds University in England and Douglas Altman of Cancer Research United Kingdom, said, "The prospect that vitamin pills might not only do no good but also kill their consumers is a scary proposition given the vast quantities used in certain communities."
If the findings are correct, "9,000 in every million users of such supplements will die prematurely as a result," the editorial said. But it added the review "is a work in progress and does not offer convincing proof of hazard."
Eric Jacobs, a senior epidemiologist at the American Cancer Society, said, "There are other things [that] do work in preventing gastrointestinal cancer. One way to prevent colon cancer is to get screened for it. Quitting smoking helps prevent colon cancer as well as lung cancer, and maintaining proper weight can reduce the risk of gastrointestinal cancer."
Posted 02 October 2004 - 04:26 PM
Posted 02 October 2004 - 06:44 PM
The POSITIVE effects of vitamin E (and other anti-oxidants) are very well documented.
I feel good when I take my vitamins...I rarely get sick..I'm gonna keep taking them for sure.
Current Skin-Care Regimen (A work in progress):
Gentle wash with DKR cleanser
Benzoyl Peroxide 2.5% (Following Dan's Regimen)
DKR Lotion + A squirt of Argan or Grapeseed oil (The lotion alone wasn't hydrating enough)
Skin 79 Korean BB Cream (excellent stuff)
Gentle Wash with DKR Cleanser
Benzoyl Peroxide 2.5% (Following Dan's Regimen)
DKR Lotion + A squirt of Argan or Grapeseed oil
Posted 02 October 2004 - 08:01 PM
Posted 02 October 2004 - 09:34 PM
Of course, there are supplements that boost apoptosis and have been linked to improved immunity and decreasing cancer, that also help eliminate acne. So just take more of those ;-)
Stage 1 (Treatment):
* (Daily) Isocare Skin Control Cleanser, Dream Products Customized Natural Face Lotion & Coppertone Sport Spray Sunscreen (mixed)
* (Sporadically) spot treat w/ anti-inflammatory (neosporin, hydrocortisone, salicylic acid) or a skin lightener (post-inflammatory pigmentation) to treat stubborn cystic/nodular acne that appears due to unknowingly or knowingly ingesting a food/ingredient that breaks me out (I do my best to avoid these foods). If you cover treated area w/ a bandaid, it makes product more effective.
Stage 2 (Prevention): "cheapest" method ~ Since Aug. 2002
* Follow a Gluten-Free, Trans-Fat Free, Dairy-Free and No Added Sugar diet for my Insulin Resistance/Hyperandrogenism (Silent Chronic Inflammatory Syndrome)
* Avoid ALL types of nuts and the Genus Prunus (almonds, plums, peaches, nectarines, apricots, cherries), Bananas, Pineapples, Cottonseed oil, Artificial Sweetners.
Stage 3 (Correction):
* 1/18/08 Ultimate Colon Cleanse (30 day program)
* Developing functional foods for those with acne & other special needs (assuming there's a defficiency).
* Developing good & "safe" formulas for various hormonal issues for women. Correction stage may resolve this for some.
Posted 03 October 2004 - 02:05 AM
Posted 03 October 2004 - 03:51 PM
1) wash with paula's choice normal to oily cleanser
2) Napca mist from twinlab or the one from nuskin and spray many times to get a good layer of moisture.
3)Avalon organics revitalizing eye gel
4)Cory Minerals (I've found that the secret to cory is to use ur brush to really swirl it around to grind the powder down even finer than it is and then to tap off the excess and start off with thin layers and build.) i also will take a concealer brush and dab it on certain areas that i need to cover up more thickly and then use a bronzer with a big bronzer brush to blend. ( i use estee lauder bronze goddess). i use bronzer all over and this seems to even out everything.
5)Aquaphor for lips.
1)Same PC N/O
2b)some nights I mask with aspirin mixed with milk of magnesia and nuetrogena clear pore cleanser mask in nose and chin area - to make mask i use a small spray bottle with distilled water that i always keep in my bathroom and i take about 8 aspirin in the palm of my hand and spray and mush with my fingers until it is a thick paste. i then add a drop of MOM and put a small amount of neut. clear pore cleanser mask. don't use mask every night.
3)Aubrey organics Vegecol toner
4)Spot treat w/ prosacea gel
5)same on eyes and lips as AM
Posted 07 October 2004 - 01:09 AM