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Spironolactone And Yaz

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Hello, this is my first forum post!

A little background on me, I'm 29 years old and have been dealing with moderate to severe cystic acne for many years, with a few good years in between. I've been on and used just about every acne medication under the sun. I've been on Accutane twice. I came off my last treatment about 10 months ago. The results lasted about 5-6 months but the last 4-5 months, it's been coming back. I was on Trisprintec and minocycline for a few months and that sorta seemed to help keep it at bay. But then I ran out of my sample packs and screwed up my BCP and my skin went sorta nuts after that.

I saw my Derm last week and she's started me on Yaz BC and 100mg Spironolactone daily. I've been on this combo for a total of 5 days. My skin is breaking out something fierce. Does anyone know if initial breakout is common with this sort of treatment with just so little days in? When can I expect to see some change in my skin? If you can give me some insight, I'd really appreciate it. Thanks in advance for your help.

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I had IBs when I first started Spiro, as well. From what I gather, it's fairly typical. My skin drastically changed for the better after about 5-6 months. I've been on it now for over 2 years and don't intend to ever get off it, except for when I plan on getting pregnant. For some people, spiro is a miracle drug completely curing them of their acne, but be patient. I've heard it taking as long as 9 months to really show results. I've also learned that it's very important to take your doses at the same time everyday, be consistent.

Goodluck to you, I hope it's the answer you've been looking for!


"I'm selfish, impatient, and a little insecure. I make mistakes, I'm out of control, and at times hard to handle. But if you can't handle me at my worst, then you sure as hell don't deserve me at my best." -Marilyn Monroe


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I had IBs when I first started Spiro, as well. From what I gather, it's fairly typical. My skin drastically changed for the better after about 5-6 months. I've been on it now for over 2 years and don't intend to ever get off it, except for when I plan on getting pregnant. For some people, spiro is a miracle drug completely curing them of their acne, but be patient. I've heard it taking as long as 9 months to really show results. I've also learned that it's very important to take your doses at the same time everyday, be consistent.

Goodluck to you, I hope it's the answer you've been looking for!

Hi and thanks for the reply. So I should be expecting these gnarly breakouts for 5-6 months? Or am I misunderstanding?

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I think everyone's different, but I didn't have horrible breakouts the entire first 6 months, no. I think I had maybe 2 really bad ones amongst manageable ones, but it was smooth sailing after that. It's definitely worth the wait.

I also remember it making me feel tired in the beginning, but I feel absolutely nothing when I take it now. I'm on 200mg/day. It lowered my blood pressure and also led me to lose 10lbs without doing a thing, which was a nice side effect.

Let me know if there's any other questions I can answer for you. :)


"I'm selfish, impatient, and a little insecure. I make mistakes, I'm out of control, and at times hard to handle. But if you can't handle me at my worst, then you sure as hell don't deserve me at my best." -Marilyn Monroe


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I think everyone's different, but I didn't have horrible breakouts the entire first 6 months, no. I think I had maybe 2 really bad ones amongst manageable ones, but it was smooth sailing after that. It's definitely worth the wait.

I also remember it making me feel tired in the beginning, but I feel absolutely nothing when I take it now. I'm on 200mg/day. It lowered my blood pressure and also led me to lose 10lbs without doing a thing, which was a nice side effect.

Let me know if there's any other questions I can answer for you. smile.png

Are or were you taking anything else with it? Antibiotics, BCP, topical rx?

Thanks for your help! :)

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I haven't been taking anything else in addition to it and It's made my skin SO much more manageable, not perfect, but 100x better than it was.


"I'm selfish, impatient, and a little insecure. I make mistakes, I'm out of control, and at times hard to handle. But if you can't handle me at my worst, then you sure as hell don't deserve me at my best." -Marilyn Monroe


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Hey you guys,

So I've recently started Spironolactone in combination with Ortho tri-cyclen lo. I've been on this for about almost two weeks. I DID experience an initial breakout but i was thinking it may be due to my hormones adjusting to the pill. I stil have some pimples on my face from previously, before i started spiro and birth control but they are slowly starting to dry up. I also realized that after taking Spironolactone, my skin isn't as oily as it used to be. BTW, i had REALLY oily skin. I would use blotting sheets like every 30mins...it was horrible...but now I may be down to TWO in one day...which is AWESOME!! rolleyes.gif I take 100mg daily. At first, I was scared to take the high dose so i started to increase it from 25mg. Spiro isn't giving me any bad side effects AT ALL (other than my initial breakout) My hair is ALSO less oily...which was surprising bc after just one day or even the same night, my hair would slowly get gross.

But I hope you don't give up!! 5 days is seriously too soon to judge...I say give it about two months or longer. Any other questions, let me know!

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How are you travelling with this treatment?

I have been on 100mg spiro + yasmin for just over 7 weeks now.

At first I had a huge breakout which gave me little faith of it actually working.

I went on roaccutaine 3 years ago which cleared my skin up and only lasted about 6 months.

The break out from roaccutaine was so much worse than my couple of weeks with spiro + yasmin.

I can say now at nearly 8 weeks later my skin is about 95% clear!

I haven't had an active pimple for the last 3 days and it's just looking better by the day!

No side effects from either medications.

I have also been doing a dermaquest pumpkin peel once a week on a 6 week course which has helped soothe the skin and reduce the redness. My skin feels so soft and clear. I can't wait to see what it looks like after 3-6 months of being on it.

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I have been on 100mg spiro for 4 months. I started clearing at month 3. Had the worst skin of my life months 1-3 though. Part of it was I started Retin A at the same time and had an awful IB from it.

Can't comment on spiro mixed with Yaz, though. I almost went on Yaz, but then a 23 year old friend of mine got a pulmonary embolism from it. No family history of blood clotting. I then found out how often Yaz has been sued and just went on the spiro instead.


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