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Repairing the long-term damage from Accutane

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#2521 Livetoregret

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  • Gender:Female
  • Location:SYDNEY, AUSTRALIA
  • Interests:finished taking Roaccutane December 2010.
    Takin this drug has been the worst decision I have ever made and I have regretted it every day since.
    Doseage: 60:40 mg alternating daily for 11/12 months
    Sideffects:None till course was over.
    Now - SEVERE dry/brittle hair.
    HAIRLOSS - lost at least 70% and continues...acne came back in July, worse than I ever suffered from it. I now have back, chest, neck & cheeks that are covered.
    So now Im bone dry with no natural hydration with horrific acne. As a 31 YO woman with now destroyed skin & hair.
    My side effects include: Chronic Dry mouth
    Severe dry,tight,dehydrated, ashy,mottled,discolored (yellow & red),wrinkled,scarred poorly healing skin
    Facial fat atrophy - fatloss. Hollow eyes & cheeks
  • Joined: 22-October 12

Posted 28 February 2013 - 12:07 AM

 

Potential-Stem-Cell-Treatment.png

Psoriasis

Mutations on genes cause certain cells to function differently. With psoriasis, these mutations seem to largely alter T-helper cells.

Immune System Causes of Psoriasis

In a normally functioning immune system, white blood cells produce antibodies to foreign invaders such as bacteria and viruses. These white blood cells also produce chemicals that aid in healing and fighting infective agents. But with psoriasis, special white blood cells called T-cells become overactive.

These T-cells “attack” the skin and set off a cascade of events that make the skin cells multiply so fast they start to stack up on the surface of the skin. Normal skin cells form, mature, and then are sloughed off every 30 days. But in plaque psoriasis the skin goes through this whole process in 3-6 days.

Normally T-cells produce chemicals that help heal the skin. In psoriasis, T-cells produce an abnormally large amount of these chemicals and actually cause more inflammation in the skin and joints.

How Do Environmental Triggers Affect Psoriasis?
Encountering certain environmental triggers seems to jump-start the machinery of the body’s immune system in vulnerable individuals. When you have an autoimmune disease, such as psoriasis, the machinery doesn’t confine its attack to a real invading enemy. Once the immune system gets rolling, it assaults the tissues and organs of the body with the equivalent of friendly fire.

Some of the environmental factors that seem to be able to trigger psoriasis or to cause a flare-up of the condition in someone who already has the disorder include:

Infections – Psoriasis often starts or worsens after you’ve had some kind of infection, especially one caused by streptococcus bacteria (as in “strep throat”).

Medications – Lithium, antimalaria drugs, high blood pressure medicines (called “beta blockers”) and the anti-inflammatory drug Indocid (indomethacin) are some of the drugs that seem to be possible triggers

Skin injury – Overly dry skin, sunburn, cuts and scratches sometimes seem to be able to add the insult of psoriasis to the original injury.

Stress – Some studies suggest that stress can serve as a trigger

Possible Role for Stem Cells

Stem cells and stem cell mixes such as Stromal Vascular Fraction Cells (SVF) are known to reset up-regulated genes. This is the basic defect in Psoriasis.

The up-regulated genes then stimulate an overreaction in the T-cells which produce excess inflammation in the skin and joints. Stem cells and SVF cells have been shown to decrease inflammation.

Theoretically stem cell and SVF cells will ameliorate psoriasis but not provide a “cure”.

Multiple Sclerosis and other neurological conditions

Macquarie Stem Cells is now treating patients with MS with some success. Our colleagues around the world are reporting improvements with other

neuro-degenerative disorders We are now starting to treat motor neurone disease, parkinsons, and other immune disorders.

A small study on the use of stem cells obtained from a patient’s own fat tissue in the treatment of multiple sclerosis has shown promising results. The three case studies support further clinical evaluation of stromal vascular fraction (SVF) cells in multiple sclerosis and other autoimmune conditions.

Thomas Ichim and Dr. Boris Minev worked with a team of researchers to demonstrate the possible effectiveness of SVF cells in multiple sclerosis treatment.

Minev said, “All three patients in our study showed dramatic improvement in their condition after the course of SVF therapy. While obviously no conclusions in terms of therapeutic efficacy can be drawn from these reports, this first clinical use of fat stem cells for treatment of multiple sclerosis supports
further investigations into this very simple and easily-implementable treatment methodology”.

Multiple sclerosis is an autoimmune condition, in which the body’s own defenses attack nerve cells, resulting in loss of their fatty myelin sheath. The first symptoms usually occur in young adults, most commonly in women. It is believed that SVF cells, and other stem cells, may be able to treat multiple sclerosis by limiting the immune reaction and promoting the growth of new myelin. According to Minev, “None of the presently available multiple sclerosis treatments selectively inhibit the immune attack against the nervous system, nor do they stimulate regeneration of previously damaged tissue. We’ve shown that SVF cells may fill this therapeutic gap”.

 



#2522 JosephBuchignani

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Posted 28 February 2013 - 06:19 AM

You're going to spend 9g on stem cells, which sometimes do nothing, but you won't try a 24 hour fast? That's nuts.

 

You've moved to a much higher sugar diet. Fruits have sugar. That could be your problem. 

 

You used to be a pretty girl and now you're not. Diet could be a major factor. Do the fast and find out. If you feel better, you know your "healthy" diet was wrong.

 

Before you spend 9g on stem cells, you should spend a lesser sum on THC oil. Go to a head shop and get a contact or two. They're in every major city.


Edited by JosephBuchignani, 28 February 2013 - 06:20 AM.


#2523 LillyRose7

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Posted 28 February 2013 - 08:19 AM

my dermatologist does stem cell therapy for the skin, they extract blood or something and it undergoes a process whereby they then inject it into the damaged tissues. They use it to increase fibroplasts (INCREASE, NOT simply STIMULATE)and this causes the skin to plump, and regenerate. It can be useful in gaining back loss volume/tissue etc and looking healthier.

 

my herbal doctor/colonic hydrotherapist told me that she gets a dermatologist who sends her patients after they have finished their rounds of accutane, to clear out their colon and begin a detoxification program, and she said that her accutane patients are SO dry, their colons are dry, its like their colons literally drink up the water.



#2524 IndigoRush

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Posted 28 February 2013 - 12:45 PM

Stefan,

 

Would a nutritionist be the best person to get a food allergy test done? or a gastroenterologist? or both? I havn't explored that realm yet, but i definitely believe i have food allergies. I also have a strange addiction to sushi....like real sushi...not the cooked crapped...talking raw fish and rice. I think it may have to do with the fact that it's a natural source of iodine and fatty acids....yum. 

 

The other Stef.

 

Hi...

There are tests available online, like a hair analysis, but I wouldn't trust them to be accurate.

But their is some kind of an immune-response test which can pinpoint allergies.

Haven't actually been down that route myself.

For the last week I've been eating natural yoghurt.

Seems to be helping my digestion a bit, but too early to tell.

I try to eat lots of butter because it's a good source of fat.

My skin seems quite nice at the moment.

I barely wash it, aside from using water.

I figure some people here get worse because they read information suggestion a raw vegan diet.

Though I wouldn't say eating natural foods is a bad idea, the debate is up for whether avoiding protein is smart.

I have boiled eggs and buttered toast every morning... Keeps me full for a while and the combination of carbs and protein/fat means my blood-sugar doesn't go crazy high.

 

Stef



Wow, LiveToRegret, how can you even afford $9,000? If that's Australian Dollar's I don't know how much that is in pounds, but sounds like an investment.

And it sounds like a risk.

I don't know about Stem Cells, but my opinion (from having spent large sums of money on supplements and professional help) is to avoid.

If it doesn't work out, you'll be gutted that you wasted all that money on nothing.

If it doesn't work out, you'll likely be out of money and will rely on regular income.

If the thing about potential cancer is true, that'd be a No-no for me.

 

My personal opinion is that anything that isn't natural and available for free (technically - meaning, products of Nature that aren't harvested and sold in Supermarkets) is messing with things that shouldn't be messed with. But it's your money.

 

If I were you, I'd take a break from all this and get some Sunshine and relaxation, but you live in Australia...

I live in Cold England.

 

You've never uploaded any pictures of your skin here.

I don't know why.

Nobody here is judging...


Well, I'm interested to see if it's as bad as you make out.

I don't know how bad things are for you, and I won't know without some kind of evidence.

Feed my curiosity? 



#2525 and1

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Posted 28 February 2013 - 05:26 PM

I wish I had 9 grand, I would be sippin on organic colostrum all day every day, just kidding, I will be doing that anyways as soon as I have a reasonable income ;)



#2526 MovingOn

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Posted 28 February 2013 - 06:22 PM

.


Edited by MovingOn, 26 June 2013 - 05:28 PM.


#2527 Livetoregret

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  • Gender:Female
  • Location:SYDNEY, AUSTRALIA
  • Interests:finished taking Roaccutane December 2010.
    Takin this drug has been the worst decision I have ever made and I have regretted it every day since.
    Doseage: 60:40 mg alternating daily for 11/12 months
    Sideffects:None till course was over.
    Now - SEVERE dry/brittle hair.
    HAIRLOSS - lost at least 70% and continues...acne came back in July, worse than I ever suffered from it. I now have back, chest, neck & cheeks that are covered.
    So now Im bone dry with no natural hydration with horrific acne. As a 31 YO woman with now destroyed skin & hair.
    My side effects include: Chronic Dry mouth
    Severe dry,tight,dehydrated, ashy,mottled,discolored (yellow & red),wrinkled,scarred poorly healing skin
    Facial fat atrophy - fatloss. Hollow eyes & cheeks
  • Joined: 22-October 12

Posted 28 February 2013 - 07:11 PM

I dont have 9 grand. I would be getting myself into massive debt.

 

Stef - Theres a before and after folder in my profile.

 

Chemo skin reactions explained: http://chemocare.com...-reactions.aspx

Basically, we in a nutshell.

 

Thanks for the brutal honesty Joseph :( , yeah I know Ive lost my looks since accutane, Its because my hair is destroyed, and my skin is ruined from cellular dehydration.

I do not look like the person I was 12 mnths ago - Thats not because of sugar, its because accutane has dried me out like an old boot.

Pre all this I lived on alot of the same foods but I have a sweet tooth.

I just dont see the point in depriving my body of anything it needs to try and heal itself. Cannabis oil is not going to fix the dried out skin or hair issues, I need to kick start my cell division into working again.



#2528 TaneAbomination

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Posted 28 February 2013 - 07:53 PM

@Livetoregret:  You may be wrong about THC oil.  I've read it can heal radiation burns.

 

Source: http://phoenixtears.ca/  (sorry, this is antedoctal may not be "scientific irrifutable evidence" - but still to be considered.)

 

At a minimum, it would relax you and relieve your pain.  But I understand it's extremely hard to get - unless maybe you become a medical tourist and venture to places (e.g. Netherlands) where it's available.



#2529 Livetoregret

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  • Gender:Female
  • Location:SYDNEY, AUSTRALIA
  • Interests:finished taking Roaccutane December 2010.
    Takin this drug has been the worst decision I have ever made and I have regretted it every day since.
    Doseage: 60:40 mg alternating daily for 11/12 months
    Sideffects:None till course was over.
    Now - SEVERE dry/brittle hair.
    HAIRLOSS - lost at least 70% and continues...acne came back in July, worse than I ever suffered from it. I now have back, chest, neck & cheeks that are covered.
    So now Im bone dry with no natural hydration with horrific acne. As a 31 YO woman with now destroyed skin & hair.
    My side effects include: Chronic Dry mouth
    Severe dry,tight,dehydrated, ashy,mottled,discolored (yellow & red),wrinkled,scarred poorly healing skin
    Facial fat atrophy - fatloss. Hollow eyes & cheeks
  • Joined: 22-October 12

Posted 28 February 2013 - 08:38 PM

Im pretty doubtful that smoking something is going to alleviate the issues associated with dried out skin, hair and hairloss...

I made some hash oil and all that did was the usual THC effect.

 

Speaking of colostrum though we should all be taking this one: http://colostrummax.com/



#2530 TaneAbomination

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Posted 28 February 2013 - 08:42 PM

One more thing I feel obligated to add...I mentioned in a previous post that I'm currently on a nutritional balancing program based on a hair mineral test analysis.  This program has done wonders for my skin and hair & energy levels.  For awhile, post accutane, my hair was falling out in globs - very similar to those photos Livetoregret posted - I was afraid I was going bald.  Fortnuately hair loss has slowed and my hair has returned to its silky ,shiny black mane.  Skin is flawless now, better than it was before accutane (if you can believe that.)   Unfortunately, my internal more serious issue remains but I am hoping this too will improve with time - if not I know what my alternatives are.

 

If you're interested in nutritional balancing here's some links:

 

http://www.holistic-...r-analysis.html - my nutritionalist's website.

http://www.drlwilson.... BAL INTRO.htm - about Nutritional Balancing.

http://drlwilson.com...ir analysis.htm - list of practitioners (international too!)

 

I will be upfront and say that the hair mineral analysis test & consultation was $170 and the recommended supplements usually range around $100 a month.  But it's a less expensive alternative to 9 grand stem cell therapy if you're patient & follow the program :)

 

Thanks to Stefan for this, you posted a video long time ago gave me this idea to try! 



#2531 JosephBuchignani

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Posted 28 February 2013 - 10:43 PM

Livetoregret, I'm being honest with you because I think you are a good person, but you are being lazy and defeatist. You reject easy ideas without trying them. Who cares what you think will work? You didn't think Accutane would destroy your body and it did, so obviously you are not omniscient. 

 

I have no option but to innovate. If I don't, I suffer excrutiating pain daily that threatens my will to live. There is no mercy in pain, there is only what works and what doesn't. If you don't experiment, you will never learn, and pain will keep you forever.

 

Also, you are not that bad looking now, although you were extremely pretty before. So I think diet is a factor in your depression and inertia. Your vegan fruity whatever diet is killing you.

 

I refuse to die, and I refuse to quit. When the pain gets too loud, I stop moving, but I know that it will recede, and then I will get up again. You must do this many times if you want to win.



#2532 Livetoregret

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  • Gender:Female
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  • Interests:finished taking Roaccutane December 2010.
    Takin this drug has been the worst decision I have ever made and I have regretted it every day since.
    Doseage: 60:40 mg alternating daily for 11/12 months
    Sideffects:None till course was over.
    Now - SEVERE dry/brittle hair.
    HAIRLOSS - lost at least 70% and continues...acne came back in July, worse than I ever suffered from it. I now have back, chest, neck & cheeks that are covered.
    So now Im bone dry with no natural hydration with horrific acne. As a 31 YO woman with now destroyed skin & hair.
    My side effects include: Chronic Dry mouth
    Severe dry,tight,dehydrated, ashy,mottled,discolored (yellow & red),wrinkled,scarred poorly healing skin
    Facial fat atrophy - fatloss. Hollow eyes & cheeks
  • Joined: 22-October 12

Posted 01 March 2013 - 12:22 AM

Livetoregret, I'm being honest with you because I think you are a good person, but you are being lazy and defeatist. You reject easy ideas without trying them. Who cares what you think will work? You didn't think Accutane would destroy your body and it did, so obviously you are not omniscient. 

 

I have no option but to innovate. If I don't, I suffer excrutiating pain daily that threatens my will to live. There is no mercy in pain, there is only what works and what doesn't. If you don't experiment, you will never learn, and pain will keep you forever.

 

Also, you are not that bad looking now, although you were extremely pretty before. So I think diet is a factor in your depression and inertia. Your vegan fruity whatever diet is killing you.

 

I refuse to die, and I refuse to quit. When the pain gets too loud, I stop moving, but I know that it will recede, and then I will get up again. You must do this many times if you want to win.

Thanks Joseph, I know its true and its hard to face every day.

I have watched myself look like a different person in such a short period of time due to this drug and its been nothing short of completely traumatizing.

I know you are right and I am so desperate at this stage I would do anything, but everything has turned out to be a dead end for me and it makes me want to give up I feel as though I have no hope at ever having my normal life again.

 

I dont have a vegan diet, I eat meat nearly every day, I used to not eat all day - I only ate one meal a day at dinner time.Meat, Veg, salad etc. I always restricted myself and rarely ate before 6pm before all this. But always healthy choices.

I only eat fruit through the day now to bolster vitamins and minerals, I dont feel I have benefited anything 

 

The only things Ive been dicey on trying are fasting & cannabis oil at this point. I already smoke each day to manage pain and over time its made me more and more lethargic and Im sure contributed to my depression obviously.

 

I'll do a 2 day fast strictly just taking in only water over the weekend and i'll report back  on Monday



#2533 JosephBuchignani

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Posted 01 March 2013 - 12:36 AM

Atta girl. I think you're tough. 
 
Just do a 24 hour fast, 48 is harder. I hope it reveals a major problem in your diet, that would be an easy fix. 
 
Yes, smoking weed can contribute to a decline, although it's great for pain.


#2534 acne1776

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Posted 01 March 2013 - 12:45 AM

Atta girl. I think you're tough. 
 
Just do a 24 hour fast, 48 is harder. I hope it reveals a major problem in your diet, that would be an easy fix. 
 
Yes, smoking weed can contribute to a decline, although it's great for pain.

 

No one is suggesting smoking weed will help. Eating "rick simpson oil" is what accutaneispoison says cured him.



#2535 IndigoRush

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Posted 01 March 2013 - 03:17 AM

Okay, L-T-R (LiveToRegret, Not LeftToRight)..

I've had a look at your pictures.

I'm always honest, so will be here...

You can tell a difference, but you don't look nearly as bad as I thought you would from how you've said.

You still have a lot of hair from what I can see, though I know it won't be in the healthy state it was prior to all of this.

At first, I did think your skin perhaps looked quite aged, but then I assumed you were in your early twenties like me.

At 31, I don't think you look too bad.

Take solace in what I'm saying, because I'm sure you're very hard on yourself.

I'm not pretending your skin looks how it should.

Clearly you're body is suffering somehow... But I really would advise against getting into debt.

If there was a very high chance of recovery from stem cells, I'd say Yeahhhh, do it.

But who know's if that'd really help?

 

You look exhausted in your recent pictures.

Under your eyes mostly.

Do you get much sleep/rest? 

Stress will obviously worsen this.

I'm sure you've tried an array of products, but aloe vera is such lovely stuff, I think that's the best you could use right now (meaning Aloe Vera gel).

Internally, it could help to reduce inflammation.

 

You still need to keep a fighting attitude.

You're living in fear because you've lost so much already.. You've lost faith in the World and don't really expect anything to help you.

I'm sure this is mainly because you've searched the Internet and realised there are many in the same boat and not too many shouting about cure's.

But, we will get through this.

Doesn't matter how, or when, we just will.

Listen to anything positive; don't pay attention to the negative stories.

A reminder - I used to spend hours trying to put 2 + 2 together, but I never found anything and became so much more frustrated because of it.

I read all the terrifying stories about people who developed problems years after stopping the drug.

Someone in their 20's dropped dead to a heart problem and their parent was claiming Accutane was the cause.

But it got to the tipping point where I'd read enough horror stories.

The shock value in them was gone for me.

Gradually I stopped looking for reasons to talk about this drug because I realised nobody wanted anything to do with me when I was depressed and feeling sorry for myself. At first, people are sympathetic, but then they just lost interest in you.

That can be the hardest part of depression - loneliness.

But, I used that as motivation because I didn't want to be 'that' person.

 

There might be a voice in your head while you read this saying 'Indigo doesn't know. He got off lightly with this drug. I don't want this advice. It's bullshit. I can't be positive when I look like this now.'

Maybe I got off lightly compared to some people in here, but Man, I've been to some dark places in the last several years.

I still have days where I want to kill myself.

But I have improved.

 

Why?

Mainly because I realised life is a bit of a bitch, for everyone who's given the chance to live.

This problem I have might suck at times, but another me in a parallel universe has just watched their Mother die of Cancer.

Another me is starving for food and wondering what difference it makes because they're just going to be hungry again after that. They have no education or future.

Another me has to deal with the trauma of being abused as a child. His Mother is an alcoholic and his Father is in prison for murder.

You get the point!! 

 

The more you fight against what's happening, the more resistance and the more stress.

Acceptance is hard. But necessary.

(Once again, I don't mean you accept this for the rest of your life, just as your current reality. It's about realising you can't control everything that goes on, and realising that your body doesn't need any further obstacles, so get out of the way of yourself and do your best to survive each day, finding a purpose for yourself).

 

Since starting College, I've been happier more days.

When I was working full-time in an office job, all I could think was 'This can't be it, surely. This can't be why I'm alive'. 

I'm a deep thinker like that. Others are happy to do whatever and just get drunk and have a good time at the weekends.

I wrote a couple of new songs yesterday and today am off to do the interview with that journalist... well, I think she was mentioned in here.

She's just a student at the moment but wants to talk to me about Accutane. Why not hey?

I'm in the studio recording a new song at the weekend and have a job interview soon, even if it is for somewhere way out of my comfort zone (Waiter/Bar work).

You need things to look forward to like this.

I'm excited to earn money again because I used to waste most of mine on crap that just sits on my shelves.

I want to buy a new guitar, a plane ticket to some place warm, some gig/theatre tickets...

 

You'll be okay...

 

Books I'd recommend (and most self-help books are utter shite) for you: 

1) Feel the fear and do it anyway

2) Feeling Good: The New Mood Therapy (the chapter on self-esteem is best and covers most of it)

3) At Last A Life (I'm pretty certain you must suffer from anxiety)

 

Just those three for now. 

Definitely the one's I've gained most insight and help from.


Edited by IndigoRush, 01 March 2013 - 03:23 AM.


#2536 Robert1000

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Posted 01 March 2013 - 09:56 AM

Hi guys!

 

I tried so many suppliments, no result. Eating healthy with no result. Detox with no result.

 

My eyes get irritated 2-3 times a day, the pain its so big, its a hell. Eye drops doesnt help at all.

 

I lost about 80% of my eyebrows, now i only have few hairs there....looks like shit, there's not sign of new ones growing.

 

On the head, in the temples area, the hair is receidding alot, also in the center of the head.

 

I'm really tired. I'm gonna go on PROPECIA.

 

Has anyone tried Propecia here? does it really work for accutane hair loss? please reply me. thanks guys.


Edited by Robert1000, 01 March 2013 - 09:56 AM.


#2537 Roland1968

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Posted 01 March 2013 - 11:13 AM

Hi guys!

 

I tried so many suppliments, no result. Eating healthy with no result. Detox with no result.

 

My eyes get irritated 2-3 times a day, the pain its so big, its a hell. Eye drops doesnt help at all.

 

I lost about 80% of my eyebrows, now i only have few hairs there....looks like shit, there's not sign of new ones growing.

 

On the head, in the temples area, the hair is receidding alot, also in the center of the head.

 

I'm really tired. I'm gonna go on PROPECIA.

 

Has anyone tried Propecia here? does it really work for accutane hair loss? please reply me. thanks guys.

 

same here - sometimes I think, there is no help, nor cure. we have to live with it.



#2538 Dubya_B

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Posted 01 March 2013 - 08:07 PM

@Robert1000- Well, if you insist on playing with fire by taking Propecia could you please report back if you have temporary resolution of your sexual side effects while on it?

 

A Dr. Kevin Pezzi mentioned Propecia reversed his Accutane-induced sexual side effects. This is the first and only case I'm aware of that the reversal was permanent.  I have heard a few stories of Propecia making the sexual side effects of Accutane worse.



#2539 oli girl

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Posted 01 March 2013 - 09:53 PM

Hi guys!

 

I tried so many suppliments, no result. Eating healthy with no result. Detox with no result.

 

My eyes get irritated 2-3 times a day, the pain its so big, its a hell. Eye drops doesnt help at all.

 

I lost about 80% of my eyebrows, now i only have few hairs there....looks like shit, there's not sign of new ones growing.

 

On the head, in the temples area, the hair is receidding alot, also in the center of the head.

 

I'm really tired. I'm gonna go on PROPECIA.

 

Has anyone tried Propecia here? does it really work for accutane hair loss? please reply me. thanks guys.

Did you ever go back to a physican and have lab work that you asked me about? such as hormones etc... I know your desperate, but I wouldn't jump so quick to propecia!



#2540 MovingOn

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Posted 01 March 2013 - 10:05 PM

Ummm has any female here noticed that many of our symptoms are strikingly similar to Estrogen Dominance? Not to get too out there, but i think somehow the thyroid might not cut it...I think something more hormonal is going on! For example, birth control made me SOOO ill. I've only been off it for about 4 or 5 days but i already feel a bit better.






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