Repairing the long-term damage from Accutane

8,521 posts in this topic

@ Joseph & VanceAstro: have you tried lecithin, it has a lot of choline and therefore choline riche lecithine is supposed to enable the bile to absorb fat and fatsoluble nutrients?!

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VanceAstro, I have never encountered someone whose symptoms so closely matched my own.

Indeed, there are not many people with our symptoms (couldn't find any on the internet and I've searched extensively), so maybe we got hit by some rare, idiosyncratic reaction or maybe we are suffering from a well-known - albeit undiagnosed - disease. Anyhow, I suspect "primarily painless chronic pancreatits" (although very rare; "several studies have reported painless forms in approximately 10% - 20% of well-diagnosed series"), because Non-Pancreatic Exocrine Insuficiency (steatorrhea caused by Celiac Disease, Crohn’s disease, Ulcerative Colitis, Hypercalcemia etc.) is probably less common than Pancreatic Exocrine Insuficiency (steatorrhea caused by continuous inflammation and degradation of pancreas - toxically induced).“Obstructive” pancreatitis that recovers following elimination of the obstruction is also possible. Other rare causes of chronic pancreatitis include,hyperlipidemia, pancreas divisum, hyperparathyroidism, gas-trectomy".

http://www.smw.ch/docs/pdf200x/2006/11/smw-11182.PDF

The online literature points - in most cases - to a very strong connection between fat malabsorbtion, steatorrhea and pancreatic disorder. Also, it is well known that pancreas can suffer extensively from prolonged exposure to certain drugs (vide Isotretinoin). But of course, this is just a sheer speculation and the only way to be sure is to perform CT scan and/or Endoscopic ultrasound (because lipase and amylase levels can be completely normal). Also, "Chronic pancreatitis has an annual incidence of about one person per 100x2009.gif000 in the United Kingdom and a prevalence of 3/100x2009.gif000" (ergo, "painless chronic pancreatits" is probably even rarer). But If I had to bet, I'd bet on Inflammatory Bowel Disease or Chronic Pancreatitis - both of these diseases can occur simultaneously (sic!).

I know one thing for sure - Isotretinoin destroyed my health.

Edited by VanceAstro

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VanceAstro, I have never encountered someone whose symptoms so closely matched my own.

Indeed, there are not many people with our symptoms (couldn't find any on the internet and I've searched extensively), so maybe we got hit by some rare, idiosyncratic reaction or maybe we are suffering from a well-known - albeit undiagnosed - disease. Anyhow, I suspect "primarily painless chronic pancreatits" (although very rare; "several studies have reported painless forms in approximately 10% - 20% of well-diagnosed series"), because Non-Pancreatic Exocrine Insuficiency (steatorrhea caused by Celiac Disease, Crohn’s disease, Ulcerative Colitis, Hypercalcemia etc.) is probably less common than Pancreatic Exocrine Insuficiency (steatorrhea caused by continuous inflammation and degradation of pancreas - toxically induced).“Obstructive” pancreatitis that recovers following elimination of the obstruction is also possible. Other rare causes of chronic pancreatitis include,hyperlipidemia, pancreas divisum, hyperparathyroidism, gas-trectomy".

http://www.smw.ch/docs/pdf200x/2006/11/smw-11182.PDF

The online literature points - in most cases - to a very strong connection between fat malabsorbtion, steatorrhea and pancreatic disorder. Also, it is well known that pancreas can suffer extensively from prolonged exposure to certain drugs (vide Isotretinoin). But of course, this is just a sheer speculation and the only way to be sure is to perform CT scan and/or Endoscopic ultrasound (because lipase and amylase levels can be completely normal). Also, "Chronic pancreatitis has an annual incidence of about one person per 100x2009.gif000 in the United Kingdom and a prevalence of 3/100x2009.gif000" (ergo, "painless chronic pancreatits" is probably even rarer). But If I had to bet, I'd bet on Inflammatory Bowel Disease or Chronic Pancreatitis - both of these diseases can occur simultaneously (sic!).

I know one thing for sure - Isotretinoin destroyed my health.

Great post. I think we are on to something. I have heard my docs talk multiple times about the fact that the pancreas may be the root cause, for some reason we never followed up and looked deeper into this potential issue.

My vision has deteriorated constantly for the last decade, like they mentioned in the video. Also have high triglycerides on and off, the last time I checked they were at 198, amlost 50 points above the upper limit of the reference range I believe.

As far as I can see it would make sense to do PERT (pancreatic enzyme replacement theraphy) at a low dose and then see who the body reacts. I am much less afraid of the idea of having to constantly supplement enzymes instead of UDCA.

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As far as I can see it would make sense to do PERT (pancreatic enzyme replacement theraphy) at a low dose and then see who the body reacts. I am much less afraid of the idea of having to constantly supplement enzymes instead of UDCA

Sounds reasonable.

In clinical practice, the diagnosis of Pancreatic enzyme insufficiency is usually based on an assessment of the patient’s clinical state, a self-report of bowel movements and weight loss in adults, or failure to thrive in children. Pancreatic enzyme replacement therapy (PERT) can be trialled, and symptom improvement would support a diagnosis of Pancreatic enzyme insufficiency.

https://www.mja.com.au/journal/2010/193/8/management-pancreatic-exocrine-insufficiency-australasian-pancreatic-club

PS. Have you had a colonoscopy?

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As far as I can see it would make sense to do PERT (pancreatic enzyme replacement theraphy) at a low dose and then see who the body reacts. I am much less afraid of the idea of having to constantly supplement enzymes instead of UDCA

Sounds reasonable.

>>In clinical practice, the diagnosis of Pancreatic enzyme insufficiency is usually based on an assessment of the patient’s clinical state, a self-report of bowel movements and weight loss in adults, or failure to thrive in children. Pancreatic enzyme replacement therapy (PERT) can be trialled, and symptom improvement would support a diagnosis of Pancreatic enzyme insufficiency.

https://www.mja.com.au/journal/2010/193/8/management-pancreatic-exocrine-insufficiency-australasian-pancreatic-club

PS. Have you had a colonoscopy?

Have not had one, had doctors wanting to do one, but then other doctors told me about how you can catch diseases from these things and so on. Kinda got scared. But I am contemplating to do one sooner or later, because my digestive issues are all to obvious and probiotics have never helped.

As I mentioned a few posts earlier, the only thing that ever brought back dark brown stools that resembled sausages was liver flushing, I am contemplating doing that again. UDCA produced sausages, but far lighter in color, although they would constantly get darker over time. But liver flushing sometimes - not always - made the stool nice dark brown.

The liv52 which I am taking together with a mix of Silymarin and TMG (Betaine) also makes my stool fairly dark. Far darker than it would get using only UDCA, however Silymarin and TMG don't produce sausages lol like UDCA does.

Edited by Undergroundwellness
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I am a nurse and have worked with many hospitalized patients with pancreatitis. The first line treatment IS fasting - completely resting the pancreas. This is done in the hospital with intravenous fluids/electrolytes infused. Slowly food is reintroduced, starting with just clear liquids. A good chicken broth made with bones simmered for hours would be a good choice. When patients are ready to eat solid food they are usually given pancreatic enzyme tabs to take with meals to aid digestion (called "pancrealipase). Bile is made in the liver, stored in the gall bladder and released into the small intestine via the bile duct. It does help digest fats and shouldn't be affected by pancreatitis. They are usually not told to eat zero fat, but are advised to be on a low fat diet.

People who have had pancreatitis once are prone to relapses. It is very important that he completely avoid alcohol, since that is strongly associated with developing this disease. If he is starting to feel a twinge of relapse coming on, he should start fasting and see if it calms down by itself. With pancreatitis, the inflammation causes tissue damage and the digestive enzymes are then released into the surrounding tissue, causing autodigestion which first starts in the pancreas itself, but can spread to surrounding tissues causing major internal damage. This is not a disease to take lightly. EAting stimulates the production and release of digestive enzymes and if the pancreas is damaged by inflammation, some of those enzymes spill out into the wrong place, causing more autodigestion. That is why fasting is so important with a flare up.

http://www.marksdailyapple.com/forum/thread9327.html

Edited by Undergroundwellness
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So after tried everything, i can tell that isopathy is working, even if i don't know how. But detoxification is still the main thing/indispensable. I've used this, isotretinoin doses: 1rst day: 30k, 3rd: 200k, 5th: XM, 7th: XMK. but 4 days between each work too. I've take kombucha (to prevent reabsorption) and drainors in the same times. I added nux vomica too.

The body should be able to excrete the poison, so if he's tired or too much broken it can be a bad idea. I was in that case before i did the liver (10) and kidney cleanse (2). So it's a good idea to do them first i think.
For those who don't believe in homeopathy, try it and dare say it didn't worked or as no effect x)

The only annoying thing is that the body enter in a detox mode and it's not really pleasant.

Edited by anonyy

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So after tried everything, i can tell that isopathy is working. It's the best and only way, for sure. I've used this, isotretinoin doses: 1rst day: 30k, 3rd: 200k, 5th: XM, 7th: XMK. but 4 days between each work too. I've take kombucha (to prevent reabsorption) and drainors in the same times. I added nux vomica too.

The body should be able to excrete the poison, so if he's tired or too much broken it can be a bad idea. I was in that case before i did the liver (10) and kidney cleanse (2). So it's a good idea to do them first i think.

For those who don't believe in homeopathy, try it and dare say it didn't worked or as no effect x)

The only annoying thing is that the body enter in a detox mode and it's not really pleasant.

Sounds good can you explain in a bit more detail what you did and how it affects you, how it improved your situation?

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I can try. I'm french i don't talk english very well.

It's like my brain and body is able to function without disruption, i feel my mind clear, with a much more large panel of feelings and emotions, memory work a lot better, i remember things i forgot about my past, remember who i am i can say. For example i can feel again the need-to-sleep/sleepy feeling that i never experienced again since a long time ago.

I just hope that it doenst just mobilize the accutane without expelling it (like the mercurius). That's why i take kombucha and other things to prevent reabsorption and to expell it correctly.

Edited by anonyy

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Joeseph are you still taking Blue Ice ? if so are you still seeing benefits ?

Edited by Gladiatoro

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Here it goes my first post on the accutane.. Let me give you a brief introduction about myself.

I was on accutane for 3 months - 40mg... I had to quit the course in between as I started getting the side effects like falling hair/ muscle pain.. I have been struggling since then to get rid of these effects without success for last 2.5 years... The accutane did wonders on my skin but had to pay a big penalty for it in terms of my muscle pain... I generally get pain in the neck on/off particularly severe in winters and also my knees... Also, my test results are normal , the kidneys, the liver .. The knees also don't show any damage in the x-rays . They are clean..

Following is the theory for accutane that i had come up with. Let me know if it makes sense or not..--

1. What is accutane?

-- Accutane is synthetic form of Vitamin A..

http://en.wikipedia.org/wiki/Accutane

2. What accutane has done to our body?

Basically we have bombarded our body with excess of Vitamin A. "Vitamin A" is a fat soluble vitamin so it goes to our liver and get's stored in our liver. The liver is responsible for cleaning all the toxins in our body or our cells. So, now our all the cells are constantly bombarded with excess of vitamin A. The typical effects that it has on our body are what we get hypervitamonsis of A. One of the side effect is dry skin and with the dry skin our acne go away.

http://en.wikipedia.org/wiki/Hypervitaminosis_A

The body stores different fat soluble vitamins A,D,E,K in a certain combination. By bombarding the body with excess Vitamin A we have effectively changed the composition of our body. The Vitamin A has effectively replaced some of the other fat compositions . So, in summary we start get side effects due to deficiency of all the other fat soluble Vitamin.

The sad part is that since these are fat soluble vitamin so once you get these in our body it is very difficult to get them out of our body.

3. What can be done with our body to recover?

So, we need to bring again the balance of these fat soluble vitamins. Fat only dissolve the fat soluble vitamins. So, we need to do 2 things:

1) Remove these excess fat soluble vitamin A fat

2) Bring the other fat soluble vitamin D/E/K in our body.

The body has been corrupted with excess vitamin A over time (Consuming accutane over several months). So, we can't expect any miracles to happen to our body right away . We just need to address issue 1 and issue 2.

How do we address them? I am not sure but this is what i was thinking and currently trying

http://www.ayurveda.com/pdf/pk_intro.pdf

I don't know whether it will work or not ? But I am currently trying this panchkarma to see if the things get bad or good...

Let me know guys what do u think?

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Still taking Blue Ice, still seeing full benefits.
Switched from yogurt to true free range chicken and rice. With portion control, am normal. Portion control no longer an extreme hardship. Just have to eat reasonably.
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Accutane - Brief low-dose course ~9 years ago for ~4 months. Liver monitored, no sides.
Symptoms: Gradual onset of symptoms, peaking ~5 years ago. Extreme IBS, lost ability to eat almost everything, unable to work for 4 years. IBD diagnosis might've been possible, but avoided doctors and the prescription meds route, going for diet and supplements instead. Thought it was regular IBS, didn't realize it was Accutane until already had avoided the IBD diagnosis. Decided going back to hell just to get the diagnosis wasn't worth it. Regained enough health to work full time around May-June 2013.
Regimen summary:
Eat only
1. true free range lean chicken breast (expensive)
2. Lean white-tail shrimp (moderately expensive)
3. Glutinous rice gruel (very cheap)
All ad libitum, minimum 150g shrimp/d.
Supplements:
1. Blue Ice CLO / Butter Oil blend
2. Udca ~1-3g /d
3. Source Naturals Essential enzymes 2x per meal
4. Symbiotics Colostrum ~1/8 scoop per meal
5. Cycled topical testosterone cream
6. Topical ACV, tea tree oil (morning) and benzoyle peroxide 10% (night)
Zeitgeibers:
1. Aim to nap every 3 hours for 20 minutes
2. Match light exposure to sunrise, sunset
3. Match meals to sun


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Both of my parents are licensed, active medical practitioners. My mom is trained in Chinese Herbal Medicine

We have a few theories on what is happening (more on this later).

I'm 28 y/o male. Was naive and stupid enough to take Accutane for a year (low dose regimen). All of my current symptoms emerged after I STOPPED taking Accutane. While i was taking the drug, I never experienced any severe side effects. Only had dry lips and dry mouth. Never experienced joint pain or IBD like symptoms. This gave me a false sense safety, and I continued to take a maintenance dose of 10 mg ever other day as an desperate attempt to finally have clear skin after all these years. Let's face it, no one would ever take this drug unless they are absolutely fed up with acne and oily skin. So, I don't blame myself. Whats done is done. Let's fix the problems.

Our theory is two things can happen metabolically with this drug:

1). You get latent side effects. Everything gets processed by your liver. You take the drug. Some of it goes to you face and immediately shuts down your oil glands. The rest is then stored in your liver and fat cells. This is your body's natural defense mechanism. Body senses the intake of high dosages of Vitamin A. To protect your organs, it stores it in the liver instead of letting it wreck havoc in the rest of your body. However, eventually these chemicals are released, or they accumulate, and eventually causes symptoms. Left untreated, these symptoms get worse as it weakens your systems even more.

2). You experience side effects immediately or soon after, especially those on a high dose regimen. The drug overwhelms your liver immediately and you start to experience side effects within weeks or months of taking the drug.

In both cases, your genetics, dosage, and duration plays a factor. This is why some people get symptoms and some don't. If everyone that took accutane got sick, this drug wouldn't be on the market.

Now the drug can either still be in your body - stored in your fat cells or liver for a long time. OR the drug has already been eliminated, and the side effects you are experiencing are permanent damages it has done to your body. In either case, I think the body has a natural ability to heal or at least repair some of the damages. EVEN CHEMO PATIENTS THAT LOOSES ALL OF THEIR HAIR AND HAS THEIR INTESTINES BURNED BY RADIATION EVENTUALLY RECOVER. We can't give up.

Possible Solutions:

Our body is amazing at healing itself. Your Liver and stomach membranes are considered fast dividing cells and replaces themselves every few days. Your liver is the most resilient organ in the entire body. Liver cells replaces itself every few days - This is a medical fact. Unfortunately, Acctuane also targets these fast dividing cells.

The only solution is to strengthen your body's natural healing and detox mechanisms. There are no medication, holistic or western that is more powerful than this. There are no magic pills. I'm currently taking 10, specific Vitamins and 1 Chinese herb formula to help strengthen my intestine and joints. Remember, everything gets processed by your liver. Too much Vitamins of the wrong kind does nothing but also places additional stress on your liver.

3 months post accutane. I can't tell if my symptoms are under control. The symptoms are either progressing very slowly or my body is detoxing very slowly.

I got all of my herbal medicine from the Tillotson Institute. This is not some online vendor. This is a brick and mortar medical office that has been in practice for 20 years. Dr. Tillotson is a licensed professional and sits on the board of the Delaware Herbal and Acupuncture Committee. They are the ones that review and determine who gets an herbal/acupuncture license in the state of Delaware. Being in practice for 20 years, he has thousands of patients both in Delaware and throughout the country. Visit his website below for more information. As a sufferer of Accutane myself, I truly hope we can found solutions to fix ourselves. We are too young to be messed up like this.

*Moderator edit, URL removed - read the board rules*

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I concur with your thoughts JTM88...

Can you share with us what type of vitamin supplement / liver detoxification you are taking

Both of my parents are licensed, active medical practitioners. My mom is trained in Chinese Herbal Medicine

We have a few theories on what is happening (more on this later).

I'm 28 y/o male. Was naive and stupid enough to take Accutane for a year (low dose regimen). All of my current symptoms emerged after I STOPPED taking Accutane. While i was taking the drug, I never experienced any severe side effects. Only had dry lips and dry mouth. Never experienced joint pain or IBD like symptoms. This gave me a false sense safety, and I continued to take a maintenance dose of 10 mg ever other day as an desperate attempt to finally have clear skin after all these years. Let's face it, no one would ever take this drug unless they are absolutely fed up with acne and oily skin. So, I don't blame myself. Whats done is done. Let's fix the problems.

Our theory is two things can happen metabolically with this drug:

1). You get latent side effects. Everything gets processed by your liver. You take the drug. Some of it goes to you face and immediately shuts down your oil glands. The rest is then stored in your liver and fat cells. This is your body's natural defense mechanism. Body senses the intake of high dosages of Vitamin A. To protect your organs, it stores it in the liver instead of letting it wreck havoc in the rest of your body. However, eventually these chemicals are released, or they accumulate, and eventually causes symptoms. Left untreated, these symptoms get worse as it weakens your systems even more.

2). You experience side effects immediately or soon after, especially those on a high dose regimen. The drug overwhelms your liver immediately and you start to experience side effects within weeks or months of taking the drug.

In both cases, your genetics, dosage, and duration plays a factor. This is why some people get symptoms and some don't. If everyone that took accutane got sick, this drug wouldn't be on the market.

Now the drug can either still be in your body - stored in your fat cells or liver for a long time. OR the drug has already been eliminated, and the side effects you are experiencing are permanent damages it has done to your body. In either case, I think the body has a natural ability to heal or at least repair some of the damages. EVEN CHEMO PATIENTS THAT LOOSES ALL OF THEIR HAIR AND HAS THEIR INTESTINES BURNED BY RADIATION EVENTUALLY RECOVER. We can't give up.

Possible Solutions:

Our body is amazing at healing itself. Your Liver and stomach membranes are considered fast dividing cells and replaces themselves every few days. Your liver is the most resilient organ in the entire body. Liver cells replaces itself every few days - This is a medical fact. Unfortunately, Acctuane also targets these fast dividing cells.

The only solution is to strengthen your body's natural healing and detox mechanisms. There are no medication, holistic or western that is more powerful than this. There are no magic pills. I'm currently taking 10, specific Vitamins and 1 Chinese herb formula to help strengthen my intestine and joints. Remember, everything gets processed by your liver. Too much Vitamins of the wrong kind does nothing but also places additional stress on your liver.

3 months post accutane. I can't tell if my symptoms are under control. The symptoms are either progressing very slowly or my body is detoxing very slowly.

I got all of my herbal medicine from the Tillotson Institute. This is not some online vendor. This is a brick and mortar medical office that has been in practice for 20 years. Dr. Tillotson is a licensed professional and sits on the board of the Delaware Herbal and Acupuncture Committee. They are the ones that review and determine who gets an herbal/acupuncture license in the state of Delaware. Being in practice for 20 years, he has thousands of patients both in Delaware and throughout the country. Visit his website below for more information. As a sufferer of Accutane myself, I truly hope we can found solutions to fix ourselves. We are too young to be messed up like this.

*Moderator edit, URL removed - read the board rules*



Hi Guys... I just wanted to give you a quick update.. Yesterday i went to my doctor's office and he had my stool analysed.. The results were back and according to it i was having parasitic infection of "Dietamoeba fragilis" . He said sometimes it is normal to have these parasites in my stool, if there are no symptoms.

I am so confused as what to do?

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DO NOT TAKE RETINOL IF YOU HAVE ACCUTANE SIDE EFFECTS

The blind leading the blind over here.

I'm embarking on a juice fast to cleanse from the damage accutane has caused me.

Day 3 so far, the fast will consist of lots of raw fruits and vegetables juiced with the omega 8004 juicer, lots of water, psylium husk powder and bentonite clay taken together.....to see whether the psylium and bentonite bind to the accutane in the GI tract. I've not been the toilet so far so i've ordered cascara sagrada to help me along biggrin.png

Edited by Chico Esposito

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try magnesiumsulfate (epsom) or natriumsulfate to trigger bowel movement

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DO NOT TAKE RETINOL IF YOU HAVE ACCUTANE SIDE EFFECTS

The blind leading the blind over here.

I'm embarking on a juice fast to cleanse from the damage accutane has caused me.

Day 3 so far, the fast will consist of lots of raw fruits and vegetables juiced with the omega 8004 juicer, lots of water, psylium husk powder and bentonite clay taken together.....to see whether the psylium and bentonite bind to the accutane in the GI tract. I've not been the toilet so far so I've ordered cascara sagrada to help me along biggrin.png

Joseph has been taking Blue Ice which obviously has retinol and it works for him but I had a bad experience with fish oil so I'm reluctant to try it , I think what it comes down to is accutane affects each person in a different way there is no one glove fits all scenario.... in othere words what works for some may not work or be benefitial for others , one can only find out through trial and error I guess.

Edited by Gladiatoro

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Sunnyhatesacne,

A friend of my parents is a biochemist, he said that Vitamin C, Vitamin D, and Vitamin E all alters the chemical structure of Vitamin A. The 4 Vitamins compete with each other. Excessive Vitamin A also prevents the proper metabolism of Vitamin D. Prob one of the reasons why large dosages over time causes bone damage. He suggested the best person to talk to is a nutritional scientist. So I'm gonna do that next. Here are the meds I'm currently taking. Seek professional, medical advice for your situation though. This forum is great, but not many of us here received any real medical training. Truly hope everyone finds whatever works for them to recover from this mess.

To "neutralize" Retinol A and its secondary metabolites. Again, no hard evidence to back this up - but some medical research is indicating so.

Vitamin C 1000

Vitamin B with CoQ10

Vitamin D 200mg per day

Vitamin E with all spectrums of tocotrienol

For the liver:

Liver Detox Pills

A Chinese Liver and Gallbladder Formula

Chinese mung beans (traditional detox food used for thousands of years in China)

For my Bones and Joints:

Bone Strength

Strontium

hyaluronic acid (there are reports that too much of this causes cancer. Not sure if this is true. Need to ask my parents)

Glucosamine

For my Intestine:

Same Chinese Herbal Formula

Aloe Vera

May also include Slipper Elm and DGL to help with the membrane coating. See how my liver is holding up first.

Probiotics

saccharomyces boulardii (Good fungus needed for healthy GI)

For my Eyes:

Super Zeaxinthin (Nutrition for the eyes)

Again, got all of this from the Tillotson Institute after I talked to Dr. Tillotson. Hope this helps. Also not sure if any of this is actually helping. Symptoms are def there, but changing too slowly. IBS like symptoms seem to be under control though.

I concur with your thoughts JTM88...

Can you share with us what type of vitamin supplement / liver detoxification you are taking

Both of my parents are licensed, active medical practitioners. My mom is trained in Chinese Herbal Medicine

We have a few theories on what is happening (more on this later).

I'm 28 y/o male. Was naive and stupid enough to take Accutane for a year (low dose regimen). All of my current symptoms emerged after I STOPPED taking Accutane. While i was taking the drug, I never experienced any severe side effects. Only had dry lips and dry mouth. Never experienced joint pain or IBD like symptoms. This gave me a false sense safety, and I continued to take a maintenance dose of 10 mg ever other day as an desperate attempt to finally have clear skin after all these years. Let's face it, no one would ever take this drug unless they are absolutely fed up with acne and oily skin. So, I don't blame myself. Whats done is done. Let's fix the problems.

Our theory is two things can happen metabolically with this drug:

1). You get latent side effects. Everything gets processed by your liver. You take the drug. Some of it goes to you face and immediately shuts down your oil glands. The rest is then stored in your liver and fat cells. This is your body's natural defense mechanism. Body senses the intake of high dosages of Vitamin A. To protect your organs, it stores it in the liver instead of letting it wreck havoc in the rest of your body. However, eventually these chemicals are released, or they accumulate, and eventually causes symptoms. Left untreated, these symptoms get worse as it weakens your systems even more.

2). You experience side effects immediately or soon after, especially those on a high dose regimen. The drug overwhelms your liver immediately and you start to experience side effects within weeks or months of taking the drug.

In both cases, your genetics, dosage, and duration plays a factor. This is why some people get symptoms and some don't. If everyone that took accutane got sick, this drug wouldn't be on the market.

Now the drug can either still be in your body - stored in your fat cells or liver for a long time. OR the drug has already been eliminated, and the side effects you are experiencing are permanent damages it has done to your body. In either case, I think the body has a natural ability to heal or at least repair some of the damages. EVEN CHEMO PATIENTS THAT LOOSES ALL OF THEIR HAIR AND HAS THEIR INTESTINES BURNED BY RADIATION EVENTUALLY RECOVER. We can't give up.

Possible Solutions:

Our body is amazing at healing itself. Your Liver and stomach membranes are considered fast dividing cells and replaces themselves every few days. Your liver is the most resilient organ in the entire body. Liver cells replaces itself every few days - This is a medical fact. Unfortunately, Acctuane also targets these fast dividing cells.

The only solution is to strengthen your body's natural healing and detox mechanisms. There are no medication, holistic or western that is more powerful than this. There are no magic pills. I'm currently taking 10, specific Vitamins and 1 Chinese herb formula to help strengthen my intestine and joints. Remember, everything gets processed by your liver. Too much Vitamins of the wrong kind does nothing but also places additional stress on your liver.

3 months post accutane. I can't tell if my symptoms are under control. The symptoms are either progressing very slowly or my body is detoxing very slowly.

I got all of my herbal medicine from the Tillotson Institute. This is not some online vendor. This is a brick and mortar medical office that has been in practice for 20 years. Dr. Tillotson is a licensed professional and sits on the board of the Delaware Herbal and Acupuncture Committee. They are the ones that review and determine who gets an herbal/acupuncture license in the state of Delaware. Being in practice for 20 years, he has thousands of patients both in Delaware and throughout the country. Visit his website below for more information. As a sufferer of Accutane myself, I truly hope we can found solutions to fix ourselves. We are too young to be messed up like this.

*Moderator edit, URL removed - read the board rules*



Hi Guys... I just wanted to give you a quick update.. Yesterday i went to my doctor's office and he had my stool analysed.. The results were back and according to it i was having parasitic infection of "Dietamoeba fragilis" . He said sometimes it is normal to have these parasites in my stool, if there are no symptoms.

I am so confused as what to do?

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Sunnyhatesacne,

A friend of my parents is a biochemist, he said that Vitamin C, Vitamin D, and Vitamin E all alters the chemical structure of Vitamin A. The 4 Vitamins compete with each other. Excessive Vitamin A also prevents the proper metabolism of Vitamin D. Prob one of the reasons why large dosages over time causes bone damage. He suggested the best person to talk to is a nutritional scientist. So I'm gonna do that next. Here are the meds I'm currently taking. Seek professional, medical advice for your situation though. This forum is great, but not many of us here received any real medical training. Truly hope everyone finds whatever works for them to recover from this mess.

To "neutralize" Retinol A and its secondary metabolites. Again, no hard evidence to back this up - but some medical research is indicating so.

Vitamin C 1000

Vitamin B with CoQ10

Vitamin D 200mg per day

Vitamin E with all spectrums of tocotrienol

For the liver:

Liver Detox Pills

A Chinese Liver and Gallbladder Formula

Chinese mung beans (traditional detox food used for thousands of years in China)

For my Bones and Joints:

Bone Strength

Strontium

hyaluronic acid (there are reports that too much of this causes cancer. Not sure if this is true. Need to ask my parents)

Glucosamine

For my Intestine:

Same Chinese Herbal Formula

Aloe Vera

May also include Slipper Elm and DGL to help with the membrane coating. See how my liver is holding up first.

Probiotics

saccharomyces boulardii (Good fungus needed for healthy GI)

For my Eyes:

Super Zeaxinthin (Nutrition for the eyes)

Again, got all of this from the Tillotson Institute after I talked to Dr. Tillotson. Hope this helps. Also not sure if any of this is actually helping. Symptoms are def there, but changing too slowly. IBS like symptoms seem to be under control though.

I concur with your thoughts JTM88...

Can you share with us what type of vitamin supplement / liver detoxification you are taking

Both of my parents are licensed, active medical practitioners. My mom is trained in Chinese Herbal Medicine

We have a few theories on what is happening (more on this later).

I'm 28 y/o male. Was naive and stupid enough to take Accutane for a year (low dose regimen). All of my current symptoms emerged after I STOPPED taking Accutane. While i was taking the drug, I never experienced any severe side effects. Only had dry lips and dry mouth. Never experienced joint pain or IBD like symptoms. This gave me a false sense safety, and I continued to take a maintenance dose of 10 mg ever other day as an desperate attempt to finally have clear skin after all these years. Let's face it, no one would ever take this drug unless they are absolutely fed up with acne and oily skin. So, I don't blame myself. Whats done is done. Let's fix the problems.

Our theory is two things can happen metabolically with this drug:

1). You get latent side effects. Everything gets processed by your liver. You take the drug. Some of it goes to you face and immediately shuts down your oil glands. The rest is then stored in your liver and fat cells. This is your body's natural defense mechanism. Body senses the intake of high dosages of Vitamin A. To protect your organs, it stores it in the liver instead of letting it wreck havoc in the rest of your body. However, eventually these chemicals are released, or they accumulate, and eventually causes symptoms. Left untreated, these symptoms get worse as it weakens your systems even more.

2). You experience side effects immediately or soon after, especially those on a high dose regimen. The drug overwhelms your liver immediately and you start to experience side effects within weeks or months of taking the drug.

In both cases, your genetics, dosage, and duration plays a factor. This is why some people get symptoms and some don't. If everyone that took accutane got sick, this drug wouldn't be on the market.

Now the drug can either still be in your body - stored in your fat cells or liver for a long time. OR the drug has already been eliminated, and the side effects you are experiencing are permanent damages it has done to your body. In either case, I think the body has a natural ability to heal or at least repair some of the damages. EVEN CHEMO PATIENTS THAT LOOSES ALL OF THEIR HAIR AND HAS THEIR INTESTINES BURNED BY RADIATION EVENTUALLY RECOVER. We can't give up.

Possible Solutions:

Our body is amazing at healing itself. Your Liver and stomach membranes are considered fast dividing cells and replaces themselves every few days. Your liver is the most resilient organ in the entire body. Liver cells replaces itself every few days - This is a medical fact. Unfortunately, Acctuane also targets these fast dividing cells.

The only solution is to strengthen your body's natural healing and detox mechanisms. There are no medication, holistic or western that is more powerful than this. There are no magic pills. I'm currently taking 10, specific Vitamins and 1 Chinese herb formula to help strengthen my intestine and joints. Remember, everything gets processed by your liver. Too much Vitamins of the wrong kind does nothing but also places additional stress on your liver.

3 months post accutane. I can't tell if my symptoms are under control. The symptoms are either progressing very slowly or my body is detoxing very slowly.

I got all of my herbal medicine from the Tillotson Institute. This is not some online vendor. This is a brick and mortar medical office that has been in practice for 20 years. Dr. Tillotson is a licensed professional and sits on the board of the Delaware Herbal and Acupuncture Committee. They are the ones that review and determine who gets an herbal/acupuncture license in the state of Delaware. Being in practice for 20 years, he has thousands of patients both in Delaware and throughout the country. Visit his website below for more information. As a sufferer of Accutane myself, I truly hope we can found solutions to fix ourselves. We are too young to be messed up like this.

*Moderator edit, URL removed - read the board rules*

Hi Guys... I just wanted to give you a quick update.. Yesterday i went to my doctor's office and he had my stool analysed.. The results were back and according to it i was having parasitic infection of "Dietamoeba fragilis" . He said sometimes it is normal to have these parasites in my stool, if there are no symptoms.

I am so confused as what to do?

In my perception supplements work, but you only see fairly quick results if you also make the required changes in your diet, these changes leverage the effect of the supps.

If you can afford a nutritionist that is good. Ideally you would get your DNA decoded and analysed as well as all your organs checked and then have an appropriate protocol build for you. Would cost a whole lot of money though...

Looks like a good protocol, pretty much like the protocol given for almost any disease by an MD with an alternative approach. What is missing are more supps that help the body produce glutathion, like selenium, zink, NAC, ALA, Silymarin etc.

What kind of probiotic do you take, what kind of b complex?

Edited by Undergroundwellness

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JTM88 and sunnyhatesacne thank you for your fantastic posts, and welcome too you both. Hypervitaminosis A is the cause, the excess fat soluble vitamin A is in the fat, the question is how do we get it out of the body?

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JTM88 and sunnyhatesacne thank you for your fantastic posts, and welcome too you both. Hypervitaminosis A is the cause, the excess fat soluble vitamin A is in the fat, the question is how do we get it out of the body?

It should not be so hard to get it out of the body you do it the same way you rid your body of excess minerals or heavy metals I'd suppose. For instance I recently found out that I have quite high levels of nickel in my body. I will rid my body of excess nickel by supplementing zinc and l-methionine and using a chelating agent once in a while as well as sauna. Supplementing the antagonists probably helps. Infra red saune probably also helps, because Vit A is fat soluble, IFR sauna has you sweat out more "fats" than regular sauna. There is a lot of research on IFR saunas available, mainly from Japan.

Edited by Undergroundwellness

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Day 4 and i woke up coughing up the most phlegm i've ever seen in my life, my tongue is thick white, it looks like a geography map, this is either a sign of detox or an infection, i hope the former. Bentonite clay is constipating, need cascara sagrada to arrive to get my bowels moving. I had 3 quarts of watermelon, spring greens, kale and lime juice yesterday, very nice.

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Day 4 and i woke up coughing up the most phlegm i've ever seen in my life, my tongue is thick white, it looks like a geography map, this is either a sign of detox or an infection, i hope the former. Bentonite clay is constipating, need cascara sagrada to arrive to get my bowels moving. I had 3 quarts of watermelon, spring greens, kale and lime juice yesterday, very nice.

let the bentonite soak in water before you take it. I let it soak for at least half an hour, usually I let it soak over night and then mix it with PH to make a P&B shake which I down right away. White tongue is probably detox, at least this is a detox symptom I get from for instance liv52 or lemon juice, but it gets better over time.

Edited by Undergroundwellness

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Day 4 and i woke up coughing up the most phlegm i've ever seen in my life, my tongue is thick white, it looks like a geography map, this is either a sign of detox or an infection, i hope the former. Bentonite clay is constipating, need cascara sagrada to arrive to get my bowels moving. I had 3 quarts of watermelon, spring greens, kale and lime juice yesterday, very nice.

let the bentonite soak in water before you take it. I let it soak for at least half an hour, usually I let it soak over night and then mix it with PH to make a P&B shake which I down right away. White tongue is probably detox, at least this is a detox symptom I get from for instance liv52 or lemon juice, but it gets better over time.

I think your right about the white tongue being detox, i use yerba prima bentonite clay, which is already hydrated with water so that saves a bit of time.

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Day 5 the sinuses are still the same, constantly sneezing and have had a runny nose all day. 2.5 quarts of juice today, pineapple, kale ginger juice and

apple, spring green ginger and lime juice, again it was very nice. 1 P & B shake, lots of water.

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