Therapeutic indications: KitoscellÂ® gel is indicated for the treatment of hypertrophic scars and keloid scars.
FarmacocinÃ©tica and Farmacodinamia: The active principle of KitoscellÂ® gel is 5-metil-1-fenil-2- [1H] - piridona, a synthetic molecule chemical, nonpeptide, small, that acts as regulating selective of citocinas reason why it has important antifibrÃ³ticas properties.
KitoscellÂ® gel prevents the formation with fibrÃ³tic injuries, diminishes the advance of injuries prexistentes fibrÃ³tics, and remove the fibrÃ³ticas injuries, because KitoscellÂ® has like action mechanism, the being a powerful inhibitor against the specific action of the human citocinas (TGF-Î²1, TNF-Î± PDGF. bFGF, EGF) which are directly responsible for the excessive proliferation of fibroblasts and the biomodulaciÃ³n of the healing. For being a nonprotein molecule is evidence of no formation of antibodies against this one, in this way has a minimum possibility of creating some immunogenic reaction. Pharmacokinetic studies have demonstrated that KitoscellÂ® can reach weaves easily when it is administered by oral or topical route. In gel presentation KitoscellÂ®, it penetrates effectively until arriving at the deep layers of the skin. KitoscellÂ® gel is not accumulated, still administered per prolonged periods of time.
Edited by eterna_maldicion, 24 February 2010 - 09:08 PM.