Posted 30 December 2007 - 12:26 PM
Treatment of Mild to Moderately Severe Facial Acne Vulgaris
EDWARD KESSLER, BA, KATHERINE FLANAGAN, MD, CHRISTINA CHIA, MD, CYNTHIA ROGERS, MD, AND DEE ANNA GLASER, MD
BACKGROUND Chemical peels are used as adjuvants for treatment of facial acne. No well-controlled studies have compared alpha and beta -hydroxy acid peels in the treatment of mild to moderately severe facial acne.
OBJECTIVE To compare the efficacy of a- and b-hydroxy acid chemical peels in the treatment of mild to moderately severe facial acne vulgaris.
MATERIALS AND METHODS Twenty patients were recruited in this split-face, double-blind, randomized, controlled study. An a-hydroxy acid (30% glycolic acid) was applied to one-half of the face and a b-hydroxy acid peel (30% salicylic acid) was applied contralaterally every 2 weeks for a total of six treatments. A blinded evaluator performed quantitative assessment of papules and pustules.
RESULTS Both chemical peels were significantly effective by the second treatment (po.05) and there were no significant differences in effectiveness between the two peels. At 2 months posttreatment, the salicylic acid peel had sustained effectiveness. More adverse events were reported with the glycolic acid peel after the initial treatment.
CONCLUSION The glycolic acid and salicylic acid peels were similarly effective. The salicylic acid peel had sustained effectiveness and fewer side effects. a- and b-Hydroxy acid peels both offer successful adjunctive treatment of facial acne vulgaris.
Posted 27 January 2008 - 09:57 PM
Posted 27 January 2008 - 10:01 PM
Posted 27 January 2008 - 11:12 PM
I 2nd Wynne's advice about waiting 6 months post accutane. But, when you do get a peel, they can also do blends of AHAs and BHAs - that's what my esthetician does. You don't just have to do one or the other.
Posted 28 January 2008 - 12:08 AM
Posted 29 January 2008 - 06:02 PM
Posted 29 January 2008 - 06:20 PM
I can put a link there too. Its an actual controlled research study, so I was excited to put it in the research forum (a forum I am trying to make more research-oriented and less "my own personal hypothesis about how to treat acne" forum - which seems to be the kind of info many people put in this section...)