I started looking into it because I was looking at acne.org reviews on vitamin C and saw this:
So I kept researching and found the connection directly in detail, so I figured I would share in case some of you are interested
Good article on cortisol and acne relation I found
http://www.skinandag...om/article/6263
I'll post snipets of it, since the whole article is too long to paste:
Many of you are familiar with the idea of adrenal androgens playing a role in acne. However, new concepts regarding stressors include the involvement of neuromediators that are released in response to stress. It has been proposed that a variety of neuroendocrine factors act centrally and locally at the level of the sebaceous gland to contribute to acne. That is to say, such neuromediators can stimulate sebum production,8,9 influence production of inflammatory reactions through cytokines, and cause sebocyte differentiation and proliferation.10,11 Specifically, substance P, a neurotransmitter, which stress can elicit, was shown by electron microscopy to act on sebaceous glands.9 The authors noted substance P increased the size of individual sebaceous cells and number of sebum vacuoles in differentiated sebaceous cells in these in vitro studies.
An interesting example of a specific stressor giving rise to acne and endogenous hypercortisolemia was reported in a 13-year-old girl after cardiac surgery and post-operative complications.7 In addition to her acne, she also had resultant striae.
In this case report, the patient received no corticosteroids, had a negative workup for an internal source of cortisol, had lab results supporting the endogenous increase in cortisol, and medications were excluded except for amiodarone (Cordarone), which could have heightened her response but is much less likely as a causative agent. Researchers concluded that the acne was a result of the increased cortisol.
Also how vitamin C relates to cortisol:
http://answers.googl...dview?id=252375
Another huge article but only a snipet, check it out at the link above^
that cortisol plays in the body. Cortisol is, as you said, secreted
by the adrenal glands, which are located atop the kidneys. They are
made up of an outer cortex, which secretes steroids such as cortisol,
and an inner medulla, which secretes other hormones, such as
adrenalin. As a steroid, cortisol is necessary in normal amounts for
the proper functioning of the body.
A fact sheet from Prince Henry Institute of Medical Research in
Australia says that “Cortisol has diverse important effects on all
parts of the body including:
· mood and wellbeing
· blood vessels and blood pressure
· bones
· muscles and skin
· immune cells and inflammation
· stomach and bowel function
In stress situations, cortisol maintains blood pressure and limits
inappropriate inflammation.” (
http://www.phimr.mon.../cortisone.html )
However, the article also goes on to state that the effects of excess
cortisol, which include weight gain, suppressed immune function, high
blood pressure and even diabetes, become destructive rather than
positive.
Where vitamin C comes in is that the adrenal glands use it in order to
produce various hormones. According to this technical monograph from
“Physician Formulated Rx Vitamins (with references), “The adrenal
cortex contains a large quantity of vitamin C. However these stores of
vitamin C can be rapidly depleted during times of stress, and when
ACTH is released from the pituitary (1). In animal studies marginal
vitamin C deficiencies have been found to cause an elevation of
cortisol levels (12). As previously mentioned chronic elevation of
cortisol could lead to many detrimental health conditions. Vitamin C
is vital for the synthesis of epinephrine from the amino acid
tyrosine. Epinephrine is secreted by the adrenal medulla in response
to a stressor. Epinephrine and norepinephrine are responsible for our
fight or flight response to a stressful situation. Epinephrine also
plays a role in blood pressure regulation by acting as part of an
auxiliary electron transport system for the last step of aldosterone
synthesis (13, 14). Aldosterone is a hormone involved in regulating
blood pressure, blood pH and blood volume. Supplementing with vitamin
C while under stress has been shown to have numerous beneficial
effects (15-17) . “
Cliffnotes:
Stress has shown it can directly cause acne
Cortisol is to blame
Vitamin C regulates cortisone
Also helps to relieve adrenals in the process
less acne






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