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Scarless Healing


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#5301 scarsgone2017

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Posted 07 July 2014 - 07:34 PM

Do we all still have hope to regain our scarless skin?

#5302 simjbuk

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Posted 08 July 2014 - 06:51 AM

wow that's harsh Ylem, sorry to read that, spending thousands without any change you believe. Not even a slight change in appearance for you ?

 

You seem like you speak from experience so would you say the best therapy for scarring is gradually accept things as is ?



#5303 JT1986

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Posted 08 July 2014 - 11:34 AM

FYI, Gemstone (the startup that is funding the DEX/AE HG trials) just announced that one of Gerecht Lab's alumni has joined their Technical Team. His name is Matt Davenport and he is a chemical and biomolecular engineer. In April, Gemstone announced that they would be hiring engineers this summer and it seems that they are accomplishing that goal.

The fact that they are hiring is a good sing. It's CEO, George Davis, has noted that their current research is based on the DEX/AE HG (as their foundation technology) and they would not be hiring staff if the trials were flopping.

#5304 golfpanther

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Posted 09 July 2014 - 05:29 PM

FYI, Gemstone (the startup that is funding the DEX/AE HG trials) just announced that one of Gerecht Lab's alumni has joined their Technical Team. His name is Matt Davenport and he is a chemical and biomolecular engineer. In April, Gemstone announced that they would be hiring engineers this summer and it seems that they are accomplishing that goal.

The fact that they are hiring is a good sing. It's CEO, George Davis, has noted that their current research is based on the DEX/AE HG (as their foundation technology) and they would not be hiring staff if the trials were flopping.

 

Good news for sure. Probably looking to do a lot of hiring to get ready to scale up production for the veterinary market (at least).

 

Still looking forward to hearing about how the trials have progressed in pigs.



#5305 scarsgone2017

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Posted 10 July 2014 - 05:01 AM

@golfphanter, why are u calling people pigs?

#5306 REPOLA

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Posted 10 July 2014 - 12:32 PM

The trials are on large animals (pigs)



#5307 golfpanther

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Posted 10 July 2014 - 03:32 PM

@golfphanter, why are u calling people pigs?

 

As Repola said, the trials currently being conducted are on pigs, not people.



#5308 JT1986

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Posted 10 July 2014 - 03:42 PM

Gerecht Lab's latest paper was published today: http://m.dev.biologi...4/2760.abstract

The abstract discusses biomaterials, angiogenesis and tissue regeneration: "The formation of vasculature is essential for tissue maintenance and regeneration. During development, the vasculature forms via the dual processes of vasculogenesis and angiogenesis, and is regulated at multiple levels: from transcriptional hierarchies and protein interactions to inputs from the extracellular environment. Understanding how vascular formation is coordinated in vivo can offer valuable insights into engineering approaches for therapeutic vascularization and angiogenesis, whether by creating new vasculature in vitro or by stimulating neovascularization in vivo.

In this Review, we will discuss how the process of vascular development can be used to guide approaches to engineering vasculature. Specifically, we will focus on some of the recently reported approaches to stimulate therapeutic angiogenesis by recreating the embryonic vascular microenvironment using biomaterials for vascular engineering and regeneration."

Based on that, it seems relevant to the DEX/AE HG and likely discusses it. Unfortunately, the article costs $25 and the PayPal link does not appear to be working properly, so I can't give more details.

#5309 scarsgone2017

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Posted 10 July 2014 - 11:03 PM

@golfpanther : sorry man, i thought you were being rude..

Cmon DH, be success on pigs so that we can use it immediately

#5310 CollegeKidd

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Posted 11 July 2014 - 01:16 AM

I've been very optimistic about this hydrogel, and so far nothing has happened to make it seem like I shouldn't be. 

 

Staying positive and hopeful. 



#5311 scarsgone2017

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Posted 11 July 2014 - 03:04 AM

At least dont ruin everyones hope like u did mrfranco21

#5312 acnescar123

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Posted 12 July 2014 - 01:30 AM

Mildly interesting:

 

http://www.pbs.org/w...skin-can-smell/

http://www.nature.co...jid2014273a.pdf



#5313 scarsgone2017

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Posted 13 July 2014 - 04:53 AM

No hope on scar?

#5314 scarsgone2017

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Posted 18 July 2014 - 01:47 AM

Do you guys know that back when we were babies, we can regenerate our skin scarless?

Do you guys know that we humans were capable of fully regenerate even limbs, but evolution chose for scars ?

Do you guys know that gene called p21 is currently hindering us from full regenaration?

Do you guys know that we still have dormant abilities to fully regenerate?

Damn skin, why dont u fully regenerate after all?

#5315 cycloverid

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Posted 18 July 2014 - 04:00 PM



#5316 skinregenerator

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Posted 23 July 2014 - 07:59 PM

I've been very optimistic about this hydrogel, and so far nothing has happened to make it seem like I shouldn't be. 

 

Staying positive and hopeful. 

maybe other hydrogel will work....






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