There has to be a limit to how much the hydrogel can regenerate. What if we only see complete regeneration from the dermis and up? So if we excised anything deeper there's going to be a problem.
The major hurdle I see with this gel coming to the market is money, if a company like johnsons (bandaid) picks it up it can be in out hands in no time.
“Nobody thought it was worth funding because it was such a crazy idea. Why would anyone want to put pig tissue in a human?” But profit-minded entrepreneurialism saved the day from pundit-advised conservatism. Eli Lilly and Co. and DuPuy, an orthopedic company in Indiana, put real money into the idea" - This was quoted from an article about acell (ECM) it could take up to a decade+ for dextran to come to fruitation.
Acell + Prp is doing wonders for hair restoration could we see some significant regeneration if we used this on our face after a procedure?
Recell (Spray on skin) Should be on the US market hopefully next year or year after, could we incorporate acell into this procedure to promote skin regeneration?
Could the acell provide a good breeding ground for the new skin cells to multiply while the ecm help recruit new stem cells to the wound site.
Obviously I have no evidence to back this up but surely if applying recell after ablative skin resurfacing yields better results than not applying anything at all then if we can somehow incoporate acell into it we should see even better results just like prp + acell combo for hair.
I don't expect these methods will yield complete regeneration but if we can get some solid results it will definitely draw more interest in regenerative medicine which in turn increase funding.
On a positive note hydrogel gel does seem to provide great a great healing environment for wounds and its not just BS. The link below talks about poland developing their own hydrogel called alemat. They've had small clinical trials and say their product can heal wounds upto 40% quicker. Lets hope the scientist at John Hopkins is onto something amazing with detran.