Scarless Healing

6,762 posts in this topic

Seabs, you think hydrogel is the answer?

As cited this is very exciting for those with full thickness 3rd degree burns, as usually the only wounds that heal scar free in 21 days are light 2nd degree burns which heal on their own.

I interpret Seab's answer as "Yes, Zirs it might very well be the answer.". Correct me if I'm wrong. =]

Share this post


Link to post
Share on other sites

Seabs, you think hydrogel is the answer?

As cited this is very exciting for those with full thickness 3rd degree burns, as usually the only wounds that heal scar free in 21 days are light 2nd degree burns which heal on their own.

I interpret Seab's answer as "Yes, Zirs it might very well be the answer.". Correct me if I'm wrong. sideways.gif

Yes your right. BTW I was using the cites and the information that was posted earlier to give a picture; which is better than my belief on its own...

Edited by seabs135

Share this post


Link to post
Share on other sites
Yes your right. BTW I was using the cites and the information that was posted earlier to give a picture; which is better than my belief on its own...

You know, I told this guy who is deeply unhappy about his hairloss about this hydrogel and he showed no interest. It's weird. I mean you'd think he'd at least go "Oh really? That's interesting!" but no. :shrug: lol

Share this post


Link to post
Share on other sites

Hi smile.png

Welcome again

We have the real solution here (i hope), it's call HYDROGEL shifty.gif

Share this post


Link to post
Share on other sites

Hi smile.png

hifive.gif

Welcome again

We have the real solution here (i hope), it's call HYDROGEL shifty.gif

Hey Zirs, are you French? I was just wondering since your English is sometimes not 100% and you seem to have a bit of a French 'accent'? smile.png

Share this post


Link to post
Share on other sites

Hi smile.png

hifive.gif

Welcome again

We have the real solution here (i hope), it's call HYDROGEL shifty.gif

Hey Zirs, are you French? I was just wondering since your English is sometimes not 100% and you seem to have a bit of a French 'accent'? smile.png

Yes :)

Share this post


Link to post
Share on other sites

I knew it! lol.gif Bonjour monsieur et J'espère tout va bien! I hope that's correct French. ermm.gif haha

Share this post


Link to post
Share on other sites

Well guys, I propose that from now on, we can plan how to get the formula hydrogel / Duoderm, without having to wait years and years until it goes on sale.

as we know hydrogel / DuoDERM is the solution, now we need to know how to get hydrogel / DuoDERM using homemade formulas or buying similar products.

Let us work

Share this post


Link to post
Share on other sites

Hey Scarflife smile.png thanks

DuoDERM gel they sell on that page is what we have discovered recently that regenerate the skin does not scar? or is only one component of the puzzle? its only duoderm whitout the new 'hydrogel'?

I thought that the scientific report, they said that was a tape DuoDERM film dressing that was placed on a special hydrogel gel have recently discovered, i mean , 2 components separates right? ( 1:duoderm film + 2: hydrogel gel) ?

¿maybe we must apply over the fresh scar the new hydrogel gel discover (not on sale yet), and then apply over this, this cain of duoderm FILM? : www.convatec.com/en/cvtus-duodrrngus/cvt-portallev1/0/detail/0/1444/1847/duoderm-dressing-range.html

Please i need more information, its very hard understand english web pages for me.

Thanks all.

Edited by zirs

Share this post


Link to post
Share on other sites

Oui. DuoDerm ne suffit pas. Nous avons besoin le hydrogel aussi. Je crois. peoples.gif

Share this post


Link to post
Share on other sites

Thanks Lapis

¿Any news about Hydrogel? i think this probably are a scam

Edited by zirs

Share this post


Link to post
Share on other sites

Thanks Lapis

¿Any news about Hydrogel? i think this probably are a scam

I hope it will become available and that it will work. But I think it is not likely that this will happen as so many people tried to achieve this before and none have succeeded. I might send them an e-mail too and find out what the current status is.

J'espère qu'il deviendra disponible et cela que cela fonctionnera. Mais je pense qu'il n'est pas probable que ceci se produise comme tant de personnes ont essayé de réaliser ceci avant et aucune n'a réussi. Je pourrais leur envoyer un email aussi et découvrir ce qu'est l'état actuel. Je ne sais pas si mon Français est bon parce que j'employais Babelfish cette fois. lol.gif

Edited by Lapis lazuli

Share this post


Link to post
Share on other sites

I dunno, I think that isn't the same thing as the Sharon Gerecht hydrogel. The thing from the recent article is "a hydrogel" that they invented. They didn't invent "the hydrogel". Hydrogels differ from each other and the people in the link you posted don't claim that their gel can achieve scarless healing while Sharon Gerecht and her buddies are saying theirs might just. eusa_think.gif

Edited by Lapis lazuli

Share this post


Link to post
Share on other sites

Thanks Lapis

¿Any news about Hydrogel? i think this probably are a scam

I hope it will become available and that it will work. But I think it is not likely that this will happen as so many people tried to achieve this before and none have succeeded. I might send them an e-mail too and find out what the current status is.

J'espère qu'il deviendra disponible et cela que cela fonctionnera. Mais je pense qu'il n'est pas probable que ceci se produise comme tant de personnes ont essayé de réaliser ceci avant et aucune n'a réussi. Je pourrais leur envoyer un email aussi et découvrir ce qu'est l'état actuel. Je ne sais pas si mon Français est bon parce que j'employais Babelfish cette fois. lol.gif

This is the first thing to be successful in reepithilizing mammalian tissue fully in under 21 days. And I cant cite anything that has done that.

I dunno, I think that isn't the same thing as the Sharon Gerecht hydrogel. The thing from the recent article is "a hydrogel" that they invented. They didn't invent "the hydrogel". Hydrogels differ from each other and the people in the link you posted don't claim that their gel can achieve scarless healing while Sharon Gerecht and her buddies are saying theirs might just.

Sun, gerecht etal tested two dextran hydrogels, a 60:40 ratio and a 80:20 ratio. The 60:40 though took longer to resorb than the 80:20. The key is the less time they take to resorb the better healing.

Edited by seabs135

Share this post


Link to post
Share on other sites

I dunno, I think that isn't the same thing as the Sharon Gerecht hydrogel. The thing from the recent article is "a hydrogel" that they invented. They didn't invent "the hydrogel". Hydrogels differ from each other and the people in the link you posted don't claim that their gel can achieve scarless healing while Sharon Gerecht and her buddies are saying theirs might just. eusa_think.gif

You know I was being scarcastic smile.png lol.

I don't really have the slightest clue if hydrogel works or not, it seems kinda weird that a scarfree solution doesn't involve any gene turning on or off but rather just changing its environment, surrounding it with a funny gel. The only thing giving me hope is seabs usual optimism wub.png

Edited by Scars4Life

Hey, it's Scars4Life


Share this post


Link to post
Share on other sites

I dunno, I think that isn't the same thing as the Sharon Gerecht hydrogel. The thing from the recent article is "a hydrogel" that they invented. They didn't invent "the hydrogel". Hydrogels differ from each other and the people in the link you posted don't claim that their gel can achieve scarless healing while Sharon Gerecht and her buddies are saying theirs might just. eusa_think.gif

You know I was being scarcastic smile.png lol.

I don't really have the slightest clue if hydrogel works or not, it seems kinda weird that a scarfree solution doesn't involve any gene turning on or off but rather just changing its environment, surrounding it with a funny gel. The only thing giving me hope is seabs usual optimism wub.png

Yeah, it strikes me as odd too. It seems all too simple. A bit too simple. It's sort of like for decades doctors have searched for a solution to no avail and now there's these guys from Johns Hopkins who have a hydrogel which does it, right? Which would also mean that all those people (I don't how many!) working for the US government who are trying to find a solution can stop working once this hydrogel comes out as it is the real thing: unlikely.

But we'll see.

This is the first thing to be successful in reepithilizing mammalian tissue fully in under 21 days. And I cant cite anything that has done that.

That, in and of itself, is very exciting. But I think that what will happen is that they'll do tests on larger animals and find that for some reason it doesn't work. Or if it does they'll move on to tests in humans and find that it doesn't work then. Or if it does it will only work to a degree and what we'll have is something that is a mere improvement over existing things which won't make people run to the hospital to have it used on them. That's what I'd put my money on.

But, again, we'll see.

Edited by Lapis lazuli

Share this post


Link to post
Share on other sites

I dunno, I think that isn't the same thing as the Sharon Gerecht hydrogel. The thing from the recent article is "a hydrogel" that they invented. They didn't invent "the hydrogel". Hydrogels differ from each other and the people in the link you posted don't claim that their gel can achieve scarless healing while Sharon Gerecht and her buddies are saying theirs might just. eusa_think.gif

You know I was being scarcastic smile.png lol.

I don't really have the slightest clue if hydrogel works or not, it seems kinda weird that a scarfree solution doesn't involve any gene turning on or off but rather just changing its environment, surrounding it with a funny gel. The only thing giving me hope is seabs usual optimism wub.png

Yeah, it strikes me as odd too. It seems all too simple. A bit too simple. It's sort of like for decades doctors have searched for a solution to no avail and now there's these guys from Johns Hopkins who have a hydrogel which does it, right? Which would also mean that all those people (I don't how many!) working for the US government who are trying to find a solution can stop working once this hydrogel comes out as it is the real thing: unlikely.

But we'll see.

This is the first thing to be successful in reepithilizing mammalian tissue fully in under 21 days. And I cant cite anything that has done that.

That, in and of itself, is very exciting. But I think that what will happen is that they'll do tests on larger animals and find that for some reason it doesn't work. Or if it does they'll move on to tests in humans and find that it doesn't work then. Or if it does it will only work to a degree and what we'll have is something that is a mere improvement over existing things which won't make people run to the hospital to have it used on them. That's what I'd put my money on.

But, again, we'll see.

Scaffolds dont work like drugs. Drugs react different in different species, scaffolds dont. If you look at a scaffold like integra, this remodelling stage in any mammal (human, pigs etc.) what ever is similar. The intercellular cells that are brought into the scaffold do the job and build the tissue they have to. Cow skin, cow skin, human skin, human skin etc.

Edited by seabs135

Share this post


Link to post
Share on other sites
Scaffolds dont work like drugs. Drugs react different in different species, scaffolds dont. If you look at a scaffold like integra, this remodelling stage in any mammal (human, pigs etc.) what ever is similar. The intercellular cells that are brought into the scaffold do the job and build the tissue they have to. Cow skin, cow skin, human skin, human skin etc.

The hydrogel is described as "a water-based, three-dimensional framework of polymers" that "recuits stem cells". Is that the same as a scaffold?

Share this post


Link to post
Share on other sites

Scaffolds dont work like drugs. Drugs react different in different species, scaffolds dont. If you look at a scaffold like integra, this remodelling stage in any mammal (human, pigs etc.) what ever is similar. The intercellular cells that are brought into the scaffold do the job and build the tissue they have to. Cow skin, cow skin, human skin, human skin etc.

The hydrogel is described as "a water-based, three-dimensional framework of polymers" that "recuits stem cells". Is that the same as a scaffold?

I would say that describes a scaffold. A scaffold to me is a three dimensional framework. Anyway here is a cite

http://www.pnas.org/...973108.abstract

Edited by seabs135

Share this post


Link to post
Share on other sites

Scaffolds dont work like drugs. Drugs react different in different species, scaffolds dont. If you look at a scaffold like integra, this remodelling stage in any mammal (human, pigs etc.) what ever is similar. The intercellular cells that are brought into the scaffold do the job and build the tissue they have to. Cow skin, cow skin, human skin, human skin etc.

The hydrogel is described as "a water-based, three-dimensional framework of polymers" that "recuits stem cells". Is that the same as a scaffold?

I would say that describes a scaffold. A scaffold to me is a three dimensional framework. Anyway here is a cite

http://www.pnas.org/...973108.abstract

Ah, it says so right there on the site you posted that it is a scaffold. Exciting. ^_^

Share this post


Link to post
Share on other sites

It's not a gel- It's a gelatin sheet designed a certain way to control/stimulate/manipulate the healing process. The Hydrogel-Hydrogelatin sheet is placed over the wound- A sheet of Duoderm is placed over the hydrogel sheet to keep the wound/hydrogel environment covered/clean as well as holding/securing the hydrogel sheet down over the wound.

The youtube video really explains the process involved in making a hydrogel scaffold. I hope more information about the material ingredients/creation of the "Scar Free Hydrogel" comes out. It seems like it could be possible to make it at home. Not possible for everyone, but the lab equipment used to make that sheet in the youtube video doesn't seem to be too complex.

Edited by 2001

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a New Account

Sign in

Already have an account? Sign in here.


Sign In Now