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Omega 3, 6, and 9 Fatty Acids

fish oil

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#1 NdnRomeo

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Posted 24 February 2007 - 02:18 PM

This thread is under construction.

Previously titled Fish Oil Capsules, we've learned quite a bit since we've made this thread. Especially the effects and benefits of other oils in our diet. Also due to some mis-information, I've decided to re-make this thread. Keep checking back and I will have updated this thread as soon as possible. As you can imagine it takes a lot to write it up compiling everything we've learned.

It will be a separate page where you can navigate all the information in a concise order and will have pages setup for categories of information and research on particular nutrients/oils. Then of course a clear regimen and what it exactly does. It will only have information, no ads, no products, no links.

It will be like a thread, but with side pages for better organization.

So bare with me and I will have it ready after I work out a few kinks in the regimen.

Thank you!

#2 ontherise

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Posted 24 February 2007 - 02:28 PM

thats quite interesting. i only started taking it 2 days ago so i will let you know in a couple of weeks

#3 anony.

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Posted 24 February 2007 - 02:36 PM

i used to have really oily skin until i started taking omega 3's as well. i started out with flax and have switched to fish oil since
hi

#4 AutonomousOne1980

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Posted 24 February 2007 - 02:43 PM

ert

Edited by AutonomousOne1980, 22 February 2012 - 12:16 AM.

#1.critical nutritional issues- b12(three forms exist), Calcium(yogurt, cheese or calcium phosphate supps) and vitamin d(sun or supps not to exceed 1000 iu). heme iron-most absorbable from meat only, clams are high. these are the most difficult vitamins to get and absorb. All others or about the same in difficulty in absorption. MAgnesium in our food supply is generally low as well, try natural calm supps.
#2 Fats- monounsaturated should dominate(olives), followed by polyunsaturated plant sources(nuts) but not if you have acne. the health benefits of fish oil and fish are controversial and i dont consume them due to mercury contamination and immune supression avoid processed fats if possible.
#3 Protein/amino acids- dairy and eggs best sources for tryptophan and methionine which convert to powerful antioxidants melatonin and glutathione.
#4 Carotenoids- alpha- beta carotene, beta cryptoxanthin, lutein zeaxanthin, astaxanthin. these are vital to human nutrition, carrots, butternut squash, pumpkin, chili pepper and cayenne pepper are the best sources.
#5 Regularity-BM at least once a day, Moist, large stools, 1 piece ideal, no maldigestion, no floating stools indicative of maldigested fat. HOW- insoluble fiber- wheat and cooked vegetables. soluble fiber-oats/ good bacteria ferment soluble fiber making short chain fatty acids that inhibit pathogens.
#6 Circadian cycles-Light, get up with the sun, and expose your entire body to it. darkness-melatonin is released upon the sensing of absolute darkness. sleep in a pitch black room, try to ensure 10 hours total darkness, wear sunglasses before bed. do not eat too late at night.
#7 Desirable physiological states(positive moods/emotions) do precisely what you like and what feels good to you, but not regardless of consequences, just from a perspective that, you own your life, and can determine precisely what you do with it and need not answer or ask of permission from anyone,achieving maximum autonomy and self government.

#5 AutonomousOne1980

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Posted 24 February 2007 - 02:46 PM

QUOTE(anony12 @ Feb 24 2007, 02:36 PM) View Post
i used to have really oily skin until i started taking omega 3's as well. i started out with flax and have switched to fish oil since



flax does not have epa or dha which are potent acne fighters, plus it contains oleic acid(omega 9) and linoleic acid(omega 6) linoliec acid is really bad for acne.

fish oil is absolutely perfect for what our bodys need.
#1.critical nutritional issues- b12(three forms exist), Calcium(yogurt, cheese or calcium phosphate supps) and vitamin d(sun or supps not to exceed 1000 iu). heme iron-most absorbable from meat only, clams are high. these are the most difficult vitamins to get and absorb. All others or about the same in difficulty in absorption. MAgnesium in our food supply is generally low as well, try natural calm supps.
#2 Fats- monounsaturated should dominate(olives), followed by polyunsaturated plant sources(nuts) but not if you have acne. the health benefits of fish oil and fish are controversial and i dont consume them due to mercury contamination and immune supression avoid processed fats if possible.
#3 Protein/amino acids- dairy and eggs best sources for tryptophan and methionine which convert to powerful antioxidants melatonin and glutathione.
#4 Carotenoids- alpha- beta carotene, beta cryptoxanthin, lutein zeaxanthin, astaxanthin. these are vital to human nutrition, carrots, butternut squash, pumpkin, chili pepper and cayenne pepper are the best sources.
#5 Regularity-BM at least once a day, Moist, large stools, 1 piece ideal, no maldigestion, no floating stools indicative of maldigested fat. HOW- insoluble fiber- wheat and cooked vegetables. soluble fiber-oats/ good bacteria ferment soluble fiber making short chain fatty acids that inhibit pathogens.
#6 Circadian cycles-Light, get up with the sun, and expose your entire body to it. darkness-melatonin is released upon the sensing of absolute darkness. sleep in a pitch black room, try to ensure 10 hours total darkness, wear sunglasses before bed. do not eat too late at night.
#7 Desirable physiological states(positive moods/emotions) do precisely what you like and what feels good to you, but not regardless of consequences, just from a perspective that, you own your life, and can determine precisely what you do with it and need not answer or ask of permission from anyone,achieving maximum autonomy and self government.

#6 AutonomousOne1980

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Posted 24 February 2007 - 02:55 PM

ert

Edited by AutonomousOne1980, 22 February 2012 - 12:17 AM.

#1.critical nutritional issues- b12(three forms exist), Calcium(yogurt, cheese or calcium phosphate supps) and vitamin d(sun or supps not to exceed 1000 iu). heme iron-most absorbable from meat only, clams are high. these are the most difficult vitamins to get and absorb. All others or about the same in difficulty in absorption. MAgnesium in our food supply is generally low as well, try natural calm supps.
#2 Fats- monounsaturated should dominate(olives), followed by polyunsaturated plant sources(nuts) but not if you have acne. the health benefits of fish oil and fish are controversial and i dont consume them due to mercury contamination and immune supression avoid processed fats if possible.
#3 Protein/amino acids- dairy and eggs best sources for tryptophan and methionine which convert to powerful antioxidants melatonin and glutathione.
#4 Carotenoids- alpha- beta carotene, beta cryptoxanthin, lutein zeaxanthin, astaxanthin. these are vital to human nutrition, carrots, butternut squash, pumpkin, chili pepper and cayenne pepper are the best sources.
#5 Regularity-BM at least once a day, Moist, large stools, 1 piece ideal, no maldigestion, no floating stools indicative of maldigested fat. HOW- insoluble fiber- wheat and cooked vegetables. soluble fiber-oats/ good bacteria ferment soluble fiber making short chain fatty acids that inhibit pathogens.
#6 Circadian cycles-Light, get up with the sun, and expose your entire body to it. darkness-melatonin is released upon the sensing of absolute darkness. sleep in a pitch black room, try to ensure 10 hours total darkness, wear sunglasses before bed. do not eat too late at night.
#7 Desirable physiological states(positive moods/emotions) do precisely what you like and what feels good to you, but not regardless of consequences, just from a perspective that, you own your life, and can determine precisely what you do with it and need not answer or ask of permission from anyone,achieving maximum autonomy and self government.

#7 NdnRomeo

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Posted 24 February 2007 - 02:58 PM

QUOTE(AutonomousOne1980 @ Feb 24 2007, 02:43 PM) View Post
for about 5 days ive been taking anywhere from 6-9 1200mg fish oil pills, and ive been seeing consistent results everyday.

what i have noted is that right now my skin is much softer, and a little less oily so i think that my sebum content has changed.

without over hyping this phenomena and turning it into something its not, i would still like to say that my acne is clearing up although its not dramatic it is a stable and consistent improvement at a rate of about 3% improvement per day, which compared to any other treatment ive tried is actually pretty miraculous.considering on accutane you could be breaking out for the entire six month course before you clear up.

Ive been researching omega 3s obsessively for the past week or so. And also just started this.
there is tons of scientific proof that this stuff helps or could cure acne.

so if you want it, i got it but so far all my posts seem like they are falling on deaf ears because no one understands my jibber jabber.ha

the key is to balance your omega 6 to 3 in a 1:1 ratio.

remember that sebum is fat, it would only make too much sense to see a relation to the quality of dietary fat and sebum.


Don't worry, I understand. Most of what I usually say feels that way.

I like you have been researching obsessively before I decided to add yet another part to my regimine. But after seeing how vital it was, I jumped on it! You are absolutely correct too, when you mention how flax is not good for ace, as opposed to fish containing omega 3, and how naturally we get 4x the amount of omega 6. Bringing the ratio closer to 1:1 is ideal.

Wow, you are very right, now my sebum seems to actually nourish my skin instead of cake it, feeling better than before. It's almost as if I actually enjoy it, rather than hate it.

Please do send over the information, I usually read and re-read everything, and more often save it for future reference to help others.

edit: I just realized you posted it above smile.gif Thank you! That's amazing, post more if you have some!

Also, where are the links from? If you have the sources, I want to see them too so I can post that in the future to others
Gone out of the country July 5th to August 5th

Finally Clear! < Click link for regimen
People always think the key to fighting acne is to avoid foods, but in actually it's usually what they're NOT eating that's causing it to happen. It made no sense to start with omitting the small things that MAY cause acne for SOME people. Start with the basics of nutrition. You're a human, not an accumulation of minor problems from every person! Not everyone reacts to the same foods. Not everyone has issues with wheat and such foods. Start with the basics of good nutrition and THEN see what happens, omit foods once you feel something is not working, but don't base a diet off of what to avoid, that will make you malnourished and very depressed when you have nothing left to eat! It is true that some people have issues with some foods, but remember, try it for yourself first :)

Get to the root of the problem, because acne has a relentless and endless arsenal on the surface and it is sadistic.

Testosterone is a steroid hormone from the androgen group. Omega 3 fatty acids can also help to keep the production of androgens under control. Androgens are hormones that influence sebum production and are particularly active during adolescence, which is possibly why many teenagers suffer from acne. Androgen excess may provoke or aggravate acne by inducing seborrhea (sebum). In women, androgen disorders are frequently suspected when acne is accompanied by hirsutism or irregularities of the menstrual cycle. In men, however, acne may be the only sign of androgen excess.


#8 ayla

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Posted 24 February 2007 - 03:02 PM

I just started taking fish oil properly yesterday - but all the evidence I've read seem to point this way. I'll let you all know how it goes. I'm taking 1200 mg x3 per day. I analyzed my diet to find my average omega 6/3 intake (thanks Autonomous!!) wow... 8:1 soooo..o.o.o.o.o. off.
It is like a reason that picks you up
And places you
Where you always wanted
To be.

*Moderator edit - Linking to websites other than Acne.org in your signature is not allowed*

#9 NdnRomeo

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Posted 24 February 2007 - 03:19 PM

I will start monitoring and writing out my results here in terms of clean and clear oil absorbing sheets (the only way I monitor how much oil I produce).

Once upon a time when I followed dan kern's regimine (july 06 to january):
I used to use one full sheet within one hour of cleaning my face, then 2 for the rest of the day (12 hours total)

After eating right, moisturizing and washing properly with BP (two months ago):
I used one full sheet after 3 hours and then 1 and a half more before I slept (in 12 hours total)

After adding in exercising, acv topically and internally, fruits and salads (1 month ago):
I used half a sheet after 3 hours, and then 1 more through the day ( 12 hours in total)

(2 weeks ago) I added in manual exfolation, and then (1 week ago) I added in fish oil capsules (3 a day), dropped cetaphil, just used an acv toner and aloe vera gel, and also exercised more intensely:
I use half a sheet after 6 hours, and then use the rest of that one throughout the day. But the sebum actually feels lighter, almost of a different texture and doesn't feel like it's even there anymore.

My body oil is also dropping. The oil on my back is almost gone too!

Every day it gets less and less, I'm so close, so close! 5 feet from the finish line! I need to cross over from acne prone skin to clarity conditioning.

We can do it eusa_dance.gif

I will add in one more fish oil capsule per day (4 grams in total) which is safe as well.
Gone out of the country July 5th to August 5th

Finally Clear! < Click link for regimen
People always think the key to fighting acne is to avoid foods, but in actually it's usually what they're NOT eating that's causing it to happen. It made no sense to start with omitting the small things that MAY cause acne for SOME people. Start with the basics of nutrition. You're a human, not an accumulation of minor problems from every person! Not everyone reacts to the same foods. Not everyone has issues with wheat and such foods. Start with the basics of good nutrition and THEN see what happens, omit foods once you feel something is not working, but don't base a diet off of what to avoid, that will make you malnourished and very depressed when you have nothing left to eat! It is true that some people have issues with some foods, but remember, try it for yourself first :)

Get to the root of the problem, because acne has a relentless and endless arsenal on the surface and it is sadistic.

Testosterone is a steroid hormone from the androgen group. Omega 3 fatty acids can also help to keep the production of androgens under control. Androgens are hormones that influence sebum production and are particularly active during adolescence, which is possibly why many teenagers suffer from acne. Androgen excess may provoke or aggravate acne by inducing seborrhea (sebum). In women, androgen disorders are frequently suspected when acne is accompanied by hirsutism or irregularities of the menstrual cycle. In men, however, acne may be the only sign of androgen excess.


#10 strider1

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Posted 24 February 2007 - 04:08 PM

so flax oil is bad??

I was just about to buy some. I was going to buy Udo's blend of " mix of the finest Omega 3, 6 and 9 varieties of Essential Fatty Acid sources". It is the best flax oil you can get. http://www.udoerasmu...il_blend_en.htm

so omega 6 and 9 are bad for you? what do you guys think?
Regimen- officially starting July 1st

Morning
nothing

Evening

Wash face with Aqua Glycolic Cleanser
Apply Complex 15

#11 NdnRomeo

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Posted 24 February 2007 - 04:22 PM

QUOTE(strider1 @ Feb 24 2007, 04:08 PM) View Post
so flax oil is bad??

I was just about to buy some. I was going to buy Udo's blend of " mix of the finest Omega 3, 6 and 9 varieties of Essential Fatty Acid sources". It is the best flax oil you can get. http://www.udoerasmu...il_blend_en.htm

so omega 6 and 9 are bad for you? what do you guys think?


I would stick with just fish oil. Reason being is our ratios are already out of wack, with 6 being readily being available in so many things we eat, we lack omega 3, so we don't need more of 6 smile.gif Don't know about 9
Gone out of the country July 5th to August 5th

Finally Clear! < Click link for regimen
People always think the key to fighting acne is to avoid foods, but in actually it's usually what they're NOT eating that's causing it to happen. It made no sense to start with omitting the small things that MAY cause acne for SOME people. Start with the basics of nutrition. You're a human, not an accumulation of minor problems from every person! Not everyone reacts to the same foods. Not everyone has issues with wheat and such foods. Start with the basics of good nutrition and THEN see what happens, omit foods once you feel something is not working, but don't base a diet off of what to avoid, that will make you malnourished and very depressed when you have nothing left to eat! It is true that some people have issues with some foods, but remember, try it for yourself first :)

Get to the root of the problem, because acne has a relentless and endless arsenal on the surface and it is sadistic.

Testosterone is a steroid hormone from the androgen group. Omega 3 fatty acids can also help to keep the production of androgens under control. Androgens are hormones that influence sebum production and are particularly active during adolescence, which is possibly why many teenagers suffer from acne. Androgen excess may provoke or aggravate acne by inducing seborrhea (sebum). In women, androgen disorders are frequently suspected when acne is accompanied by hirsutism or irregularities of the menstrual cycle. In men, however, acne may be the only sign of androgen excess.


#12 NdnRomeo

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Posted 24 February 2007 - 04:25 PM

Something else I found

QUOTE

I simply know that it takes 2-4 weeks (maybe more)
for those special fatty acids to replace the 'standard'
original ones in phospholipids of cell membranes and
lead to anti-aggregating & anti-inflammatory effects.
Accordingly, when you stop assuming them in your diet,
those effects persist for a few weeks.
This is what I remember from the first studies in '80s.
Some immediate anti-inflammatory effects after experi-
-mental intravenous administration have been reported.

I should check this 'cause it is just a vague memory...
You could read CLO topic and find other bits and pieces!


Maybe this has something to do with all of this as well, in terms of oil production from irritation as well? I foresee even more results in the next week or two
Gone out of the country July 5th to August 5th

Finally Clear! < Click link for regimen
People always think the key to fighting acne is to avoid foods, but in actually it's usually what they're NOT eating that's causing it to happen. It made no sense to start with omitting the small things that MAY cause acne for SOME people. Start with the basics of nutrition. You're a human, not an accumulation of minor problems from every person! Not everyone reacts to the same foods. Not everyone has issues with wheat and such foods. Start with the basics of good nutrition and THEN see what happens, omit foods once you feel something is not working, but don't base a diet off of what to avoid, that will make you malnourished and very depressed when you have nothing left to eat! It is true that some people have issues with some foods, but remember, try it for yourself first :)

Get to the root of the problem, because acne has a relentless and endless arsenal on the surface and it is sadistic.

Testosterone is a steroid hormone from the androgen group. Omega 3 fatty acids can also help to keep the production of androgens under control. Androgens are hormones that influence sebum production and are particularly active during adolescence, which is possibly why many teenagers suffer from acne. Androgen excess may provoke or aggravate acne by inducing seborrhea (sebum). In women, androgen disorders are frequently suspected when acne is accompanied by hirsutism or irregularities of the menstrual cycle. In men, however, acne may be the only sign of androgen excess.


#13 bber

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Posted 24 February 2007 - 05:16 PM

QUOTE(xxndnromeoxx @ Feb 24 2007, 05:25 PM) View Post
Something else I found

QUOTE

I simply know that it takes 2-4 weeks (maybe more)
for those special fatty acids to replace the 'standard'
original ones in phospholipids of cell membranes and
lead to anti-aggregating & anti-inflammatory effects.
Accordingly, when you stop assuming them in your diet,
those effects persist for a few weeks.
This is what I remember from the first studies in '80s.
Some immediate anti-inflammatory effects after experi-
-mental intravenous administration have been reported.

I should check this 'cause it is just a vague memory...
You could read CLO topic and find other bits and pieces!


Maybe this has something to do with all of this as well, in terms of oil production from irritation as well? I foresee even more results in the next week or two


I've experienced great results with fish oil + resveratrol, since I started them both at the same time I can't tell which one is doing the most but I'd say its the fish oil. Since I started basically 90% of my oil production has decreased, however I am taking doses way higher than what many other people have tried. I'm running 24-28g of fish oil which is about 10g of EPA/DHA a day. See my thread here if interested.
http://www.acne.org/...p...=141074&hl=
24-28 1g pills of fish oil since early Feb 07(approx 10g o3s)
30-35 1g pills since March 22(approx 15g)

#14 NdnRomeo

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Posted 24 February 2007 - 05:45 PM

QUOTE(bber @ Feb 24 2007, 05:16 PM) View Post
QUOTE(xxndnromeoxx @ Feb 24 2007, 05:25 PM) View Post
Something else I found

QUOTE

I simply know that it takes 2-4 weeks (maybe more)
for those special fatty acids to replace the 'standard'
original ones in phospholipids of cell membranes and
lead to anti-aggregating & anti-inflammatory effects.
Accordingly, when you stop assuming them in your diet,
those effects persist for a few weeks.
This is what I remember from the first studies in '80s.
Some immediate anti-inflammatory effects after experi-
-mental intravenous administration have been reported.

I should check this 'cause it is just a vague memory...
You could read CLO topic and find other bits and pieces!


Maybe this has something to do with all of this as well, in terms of oil production from irritation as well? I foresee even more results in the next week or two


I've experienced great results with fish oil + resveratrol, since I started them both at the same time I can't tell which one is doing the most but I'd say its the fish oil. Since I started basically 90% of my oil production has decreased, however I am taking doses way higher than what many other people have tried. I'm running 24-28g of fish oil which is about 10g of EPA/DHA a day. See my thread here if interested.
http://www.acne.org/...p...=141074&hl=



That is very interesting, but 24 grams seems way too much, isn't that overdose? Have you found any links as to what can happen if you take that much?
Gone out of the country July 5th to August 5th

Finally Clear! < Click link for regimen
People always think the key to fighting acne is to avoid foods, but in actually it's usually what they're NOT eating that's causing it to happen. It made no sense to start with omitting the small things that MAY cause acne for SOME people. Start with the basics of nutrition. You're a human, not an accumulation of minor problems from every person! Not everyone reacts to the same foods. Not everyone has issues with wheat and such foods. Start with the basics of good nutrition and THEN see what happens, omit foods once you feel something is not working, but don't base a diet off of what to avoid, that will make you malnourished and very depressed when you have nothing left to eat! It is true that some people have issues with some foods, but remember, try it for yourself first :)

Get to the root of the problem, because acne has a relentless and endless arsenal on the surface and it is sadistic.

Testosterone is a steroid hormone from the androgen group. Omega 3 fatty acids can also help to keep the production of androgens under control. Androgens are hormones that influence sebum production and are particularly active during adolescence, which is possibly why many teenagers suffer from acne. Androgen excess may provoke or aggravate acne by inducing seborrhea (sebum). In women, androgen disorders are frequently suspected when acne is accompanied by hirsutism or irregularities of the menstrual cycle. In men, however, acne may be the only sign of androgen excess.


#15 bber

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Posted 24 February 2007 - 05:51 PM

QUOTE(xxndnromeoxx @ Feb 24 2007, 06:45 PM) View Post
QUOTE(bber @ Feb 24 2007, 05:16 PM) View Post
QUOTE(xxndnromeoxx @ Feb 24 2007, 05:25 PM) View Post
Something else I found

QUOTE

I simply know that it takes 2-4 weeks (maybe more)
for those special fatty acids to replace the 'standard'
original ones in phospholipids of cell membranes and
lead to anti-aggregating & anti-inflammatory effects.
Accordingly, when you stop assuming them in your diet,
those effects persist for a few weeks.
This is what I remember from the first studies in '80s.
Some immediate anti-inflammatory effects after experi-
-mental intravenous administration have been reported.

I should check this 'cause it is just a vague memory...
You could read CLO topic and find other bits and pieces!


Maybe this has something to do with all of this as well, in terms of oil production from irritation as well? I foresee even more results in the next week or two


I've experienced great results with fish oil + resveratrol, since I started them both at the same time I can't tell which one is doing the most but I'd say its the fish oil. Since I started basically 90% of my oil production has decreased, however I am taking doses way higher than what many other people have tried. I'm running 24-28g of fish oil which is about 10g of EPA/DHA a day. See my thread here if interested.
http://www.acne.org/...p...=141074&hl=



That is very interesting, but 24 grams seems way too much, isn't that overdose? Have you found any links as to what can happen if you take that much?


I don't know, I figure since its a balancing act between omega 3s and omega 6s and I eat meat and animal products roughly 5 times a day 24 grams might be adequate for me. If you have a much lower consumption of omega 6s(ie animal products/meats) then your dose should be lower, I think. But Im really not sure, its all just assumptions at this point, experiment and see what works for you.
24-28 1g pills of fish oil since early Feb 07(approx 10g o3s)
30-35 1g pills since March 22(approx 15g)

#16 Got2BStrong14

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Posted 24 February 2007 - 06:17 PM

I normally steer clear of seafood (even though I LOVE it) because of the iodine. Do fish oil capsules contain iodine? I have them and was taking them w/ multivitamins around a time that I had a really bad break out so I stopped taking them and have cleared up somewhat since. But maybe it was unrelated.

#17 ayla

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Posted 24 February 2007 - 06:38 PM

QUOTE
The University of Iowa Cancer Center, Iowa City, 52242, USA. c-burns@uiowa.edu

The purpose of this study was to determine the maximum tolerated dose and dose-limiting toxicities of fish oil fatty acid capsules containing omega-3 fatty acid ethyl esters. Twenty-two patients with neoplastic disease not amenable to curative therapy who had lost 2% of body weight over a previous 1 month time period were given an escalating dose of fish oil fatty acids. The maximum tolerated dose was found to be 0.3 g/kg per day of this preparation. This means that a 70-kg patient can generally tolerate up to 21 1-g capsules/day containing 13.1 g of eicosapentaenoic acid + docosahexaenoic acid, the two major omega-3 fatty acids. Dose-limiting toxicity was gastrointestinal, mainly diarrhea, and a poorly described toxicity designated as "unable to tolerate in esophagus or stomach." A patient with chronic lymphocytic leukemia taking the fish oil provided an unusual opportunity to perform a detailed biochemical study of the effect of fish oil capsules on the lipids of malignant cells at several sequential time points in treatment. Studies of the malignant lymphocytes, serum, and whole blood of this one patient revealed an increase in eicosapentaenoic acid, the major component of the fish oil capsules, during fish oil capsule treatment. This study provides a scientific basis for the selection of omega-3 fatty acid doses for future studies in cancer. The maximum tolerated dose found is considerably higher than anticipated from published studies of many human diseases. The observation of a modification of the lipids of leukemic cells, serum, and blood in a patient with chronic leukemia provides a biochemical basis for a possible effect of fish oil supplements on cancer cachexia and tumor growth.


link: http://www.ncbi.nlm....p;dopt=Abstract


QUOTE
Prisco D; Paniccia R; Bandinelli B; Filippini M; Francalanci I; Giusti B; Giurlani L; Gensini GF; Abbate R; Neri Serneri GG
Institute of Clinica Medica Generale e Cardiologia, University of Florence, Italy.

Several studies have shown that n-3 polyunsaturated fatty acids (n-3 PUFA) are able to lower blood pressure (BP) in humans, but large doses of fish oils have been often used. Moreover, most of the studies available in the literature were not able to evaluate the specific effects of n-3 PUFA because they employed fish oils which contain, together with n-3 PUFA, many other different components. The aim of this preliminary study was to evaluate if medium-term supplementation with a moderate dose of highly purified eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) ethyl esters is able to reduce BP in mild hypertensive patients. Sixteen mild essential hypertensive (diastolic BP: 95-104 mm Hg), non-diabetic, normolipidemic male outpatients and 16 normotensive male controls were recruited to participate in the study. Both hypertensive and control subjects were randomly assigned to receive either EPA and DHA ethyl esters (2.04 g EPA and 1.4 g DHA) as active treatment or olive oil (4 g/day) as a placebo for a period of 4 months. These subjects were followed up with 24-hour ambulatory BP monitoring and blood chemistry analyses at 2 and 4 months of treatment and 2 months after its discontinuation. The intake of n-3 PUFA was checked by red blood cell (RBC) phosphatidylcholine (PC) fatty acid composition. The effect of n-3 PUFA on BP in the active group was maximum after 2 months. Both systolic (-6 mm Hg, p<0.05) and diastolic (-5 mm Hg, p<0.05) BP significantly decreased during the n-3 PUFA ethyl ester supplementation. No further effect was observed at 4 months with a return to baseline values during the recovery period. These data indicate that 4 g/day of highly purified EPA + DHA ethyl esters are able to favorably affect BP in mild hypertensives.



link: http://www.medscape....bstract/9733153



QUOTE
Young GS; Conquer JA; Thomas R
Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ontario N1G 5B6, Canada.

Dietary intake of omega-3 fatty acids has been positively correlated with cardiovascular and neuropsychiatric health in several studies. The high seafood intake by the Japanese and Greenland Inuit has resulted in low ratios of the omega-6 fatty acid arachidonic acid (AA, 20:4n-6) to eicosapentaenoic acid (EPA, 20:5n-3), with the Japanese showing AA:EPA ratios of approximately 1.7 and the Greenland Eskimos showing ratios of approximately 0.14. It was the objective of this study to determine the effect of supplementation with high doses (60 g) of flax and fish oils on the blood phospholipid (PL) fatty acid status, and AA/EPA ratio of individuals with Attention Deficit Hyperactivity Disorder (ADHD), commonly associated with decreased blood omega-3 fatty acid levels. Thirty adults with ADHD were randomized to 12 weeks of supplementation with olive oil (< 1% omega-3 fatty acids), flax oil (source of alpha-linolenic acid; 18:3n-3; alpha-LNA) or fish oil (source of EPA and docosahexaenoic acid; 22:6n-3; DHA). Serum PL fatty acid levels were determined at baseline and at 12 weeks. Flax oil supplementation resulted in an increase in alpha-LNA and a slight decrease in the ratio of AA/EPA, while fish oil supplementation resulted in increases in EPA, DHA and total omega-3 fatty acids and a decrease in the AA/EPA ratio to values seen in the Japanese population. These data suggest that in order to increase levels of EPA and DHA in adults with ADHD, and decrease the AA/EPA ratio to levels seen in high fish consuming populations, high dose fish oil may be preferable to high dose flax oil. Future study is warranted to determine whether correction of low levels of long-chain omega-3 fatty acids is of therapeutic benefit in this population.


link: http://www.medscape....stract/16188207

Unfortunately, none these have a thing to do w/acne, but they do show some very high doses being safely taken.
It is like a reason that picks you up
And places you
Where you always wanted
To be.

*Moderator edit - Linking to websites other than Acne.org in your signature is not allowed*

#18 AutonomousOne1980

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Posted 24 February 2007 - 11:23 PM

QUOTE(strider1 @ Feb 24 2007, 04:08 PM) View Post
so flax oil is bad??

I was just about to buy some. I was going to buy Udo's blend of " mix of the finest Omega 3, 6 and 9 varieties of Essential Fatty Acid sources". It is the best flax oil you can get. http://www.udoerasmu...il_blend_en.htm

so omega 6 and 9 are bad for you? what do you guys think?



no omega 6 and 9 arent bad,but when they are out of balance they are plenty bad, you just need them in the right quantitys.

here is chart illustrating how these fats compete with each other for the same enzymes to acheive balance, http://en.wikipedia....Eicosanoids.svg and which fats lead to either pro or anti-inflammatory eicosanoids.
#1.critical nutritional issues- b12(three forms exist), Calcium(yogurt, cheese or calcium phosphate supps) and vitamin d(sun or supps not to exceed 1000 iu). heme iron-most absorbable from meat only, clams are high. these are the most difficult vitamins to get and absorb. All others or about the same in difficulty in absorption. MAgnesium in our food supply is generally low as well, try natural calm supps.
#2 Fats- monounsaturated should dominate(olives), followed by polyunsaturated plant sources(nuts) but not if you have acne. the health benefits of fish oil and fish are controversial and i dont consume them due to mercury contamination and immune supression avoid processed fats if possible.
#3 Protein/amino acids- dairy and eggs best sources for tryptophan and methionine which convert to powerful antioxidants melatonin and glutathione.
#4 Carotenoids- alpha- beta carotene, beta cryptoxanthin, lutein zeaxanthin, astaxanthin. these are vital to human nutrition, carrots, butternut squash, pumpkin, chili pepper and cayenne pepper are the best sources.
#5 Regularity-BM at least once a day, Moist, large stools, 1 piece ideal, no maldigestion, no floating stools indicative of maldigested fat. HOW- insoluble fiber- wheat and cooked vegetables. soluble fiber-oats/ good bacteria ferment soluble fiber making short chain fatty acids that inhibit pathogens.
#6 Circadian cycles-Light, get up with the sun, and expose your entire body to it. darkness-melatonin is released upon the sensing of absolute darkness. sleep in a pitch black room, try to ensure 10 hours total darkness, wear sunglasses before bed. do not eat too late at night.
#7 Desirable physiological states(positive moods/emotions) do precisely what you like and what feels good to you, but not regardless of consequences, just from a perspective that, you own your life, and can determine precisely what you do with it and need not answer or ask of permission from anyone,achieving maximum autonomy and self government.

#19 acne_battle

acne_battle

    this is Ollie, my parents cat which I took a pic of on my b day

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Posted 24 February 2007 - 11:25 PM

I got a question about that. On Friday I purchased Omega 3 Fish oil supplements from GNC (1000 mgs) It says on the bottle to take it once to twice a day. If I took it three times a day is that considered an overdose? Sorry if thats a stupid question but I need to know the answer
My regimen changed (starting 5/16/09) and I am not a happy camper

AM regimen
Wash face and chest with Kaiser 5% bp wash
Moisturize with face reality skincare cranberry cream
Apply Estee Lauder Future Perfect Eye Cream
Apply make up, blush, finishing powder, MAC moisture cover to dark underyeye circles
Pop a doxycycline

PM regimen
Remove make up with desert esscence jojoba oil using cotton balls
starting evening of May 28, 2009, I wash my face with Face Reality Skincare Sensitive Skin Gel Cleanser at night time only
Apply Differin to face and chest
Wait to dry and moisturize with face reality skincare cranberry cream
Apply Estee Lauder Future Perfect Eye Cream
Pop a doxycycline

Foundation- MAC Studio Tech Foundation in NC20 or MAC Studio Sculpt Foundation in NW15, apply a MAC blush, apply MAC prep and prime finishing powder


Anyone who has a problem zit thats having a hard time healing, try this and let me know if it helped you. Mix one tablespoon of sea salt with three tablespoons of warm water, apply to a cotton ball or a paper towel. Apply to the zit for ten to fifteen minutes, and then wash it off.

#20 AutonomousOne1980

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Posted 24 February 2007 - 11:36 PM

QUOTE(bber @ Feb 24 2007, 05:16 PM) View Post
QUOTE(xxndnromeoxx @ Feb 24 2007, 05:25 PM) View Post
Something else I found

QUOTE

I simply know that it takes 2-4 weeks (maybe more)
for those special fatty acids to replace the 'standard'
original ones in phospholipids of cell membranes and
lead to anti-aggregating & anti-inflammatory effects.
Accordingly, when you stop assuming them in your diet,
those effects persist for a few weeks.
This is what I remember from the first studies in '80s.
Some immediate anti-inflammatory effects after experi-
-mental intravenous administration have been reported.

I should check this 'cause it is just a vague memory...
You could read CLO topic and find other bits and pieces!


Maybe this has something to do with all of this as well, in terms of oil production from irritation as well? I foresee even more results in the next week or two


I've experienced great results with fish oil + resveratrol, since I started them both at the same time I can't tell which one is doing the most but I'd say its the fish oil. Since I started basically 90% of my oil production has decreased, however I am taking doses way higher than what many other people have tried. I'm running 24-28g of fish oil which is about 10g of EPA/DHA a day. See my thread here if interested.
http://www.acne.org/...p...=141074&hl=



wow i had no idea you were taking that much!!!!!

im taking 9 a day and things are going good.

#1.critical nutritional issues- b12(three forms exist), Calcium(yogurt, cheese or calcium phosphate supps) and vitamin d(sun or supps not to exceed 1000 iu). heme iron-most absorbable from meat only, clams are high. these are the most difficult vitamins to get and absorb. All others or about the same in difficulty in absorption. MAgnesium in our food supply is generally low as well, try natural calm supps.
#2 Fats- monounsaturated should dominate(olives), followed by polyunsaturated plant sources(nuts) but not if you have acne. the health benefits of fish oil and fish are controversial and i dont consume them due to mercury contamination and immune supression avoid processed fats if possible.
#3 Protein/amino acids- dairy and eggs best sources for tryptophan and methionine which convert to powerful antioxidants melatonin and glutathione.
#4 Carotenoids- alpha- beta carotene, beta cryptoxanthin, lutein zeaxanthin, astaxanthin. these are vital to human nutrition, carrots, butternut squash, pumpkin, chili pepper and cayenne pepper are the best sources.
#5 Regularity-BM at least once a day, Moist, large stools, 1 piece ideal, no maldigestion, no floating stools indicative of maldigested fat. HOW- insoluble fiber- wheat and cooked vegetables. soluble fiber-oats/ good bacteria ferment soluble fiber making short chain fatty acids that inhibit pathogens.
#6 Circadian cycles-Light, get up with the sun, and expose your entire body to it. darkness-melatonin is released upon the sensing of absolute darkness. sleep in a pitch black room, try to ensure 10 hours total darkness, wear sunglasses before bed. do not eat too late at night.
#7 Desirable physiological states(positive moods/emotions) do precisely what you like and what feels good to you, but not regardless of consequences, just from a perspective that, you own your life, and can determine precisely what you do with it and need not answer or ask of permission from anyone,achieving maximum autonomy and self government.




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