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  1. Repairing the long-term damage from Accutane

    Retinoic acid suppresses intestinal mucus production and exacerbates experimental enterocolitis vs. Phosphatidylcholine (lecithin) and the mucus layer: Evidence of therapeutic efficacy in ulcerative colitis?
  2. Repairing the long-term damage from Accutane

    That's the point. No matter how much sunlight you get...due to the sebaceous glands being altered, you can't synthesize sulfate as much anymore. MSM is sulfur...not sulfate? chondroitin sulfate Epsom salt baths?
  3. Repairing the long-term damage from Accutane

    Interesting that retinoic acid in the skin interferes with sulfate being formed from sunlight. Could it be that accutane was stored in the skin, but not in the blood/liver? could explain a lot of the long term side effects. google sulfate deficiency symptoms. This is where sun exposure enters the picture. When you expose your skin to sunshine, your skin synthesizes vitamin D3 sulfate. This form of vitamin D is water soluble, unlike oral vitamin D3 supplements, which is unsulfated. The water soluble form can travel freely in your blood stream, whereas the unsulfated form needs LDL (the so-called “bad” cholesterol) as a vehicle of transport. Her suspicion is that the simple oral non-sulfated form of vitamin D likely will not provide the same benefits as the vitamin D created in your skin from sun exposure, because it cannot be converted to vitamin D sulfate. This is yet another reason to really make a concerted effort to get ALL your vitamin D requirements from exposure to sunshine!
  4. Repairing the long-term damage from Accutane
  5. Repairing the long-term damage from Accutane
  6. Repairing the long-term damage from Accutane

    i believe this will be the future standard for all disease in a few years. computeralgos will solve basically everything. I commend you on your work. but i personally wouldnt omit anything. you could always revise it later? every little piece of the puzzle matters...and something you omit could be the piece of information somebody out there needs.
  7. Repairing the long-term damage from Accutane

    why are some of the circles blurred in your picture?
  8. Repairing the long-term damage from Accutane

    got this reply from a company that makes ALDH. could be interesting....
  9. Repairing the long-term damage from Accutane

    i had an idea. this is similar to the TRT problem bodybuilders face. when a bodybuilder takes a steroid, their bodies shut down the ability to make natural steroids. we shouldnt be doing a TRT restart...we should be doing a retinoic acid restart??!! we took a load of retinoic acid. our bodies then shut down the enzyme needed to convert retinol to retinoic acid (AS A DEFENSE). could this be causing a backup of retinol in the liver? would this be the reason we have both vitamin A deficiency and toxicity symptoms? this could also be the reason some react so poorly to foods containing high amounts of vitamin A. One of the key signs of aldehyde excess is brain fog, which is why we call pantethine the “clear head pill.” this enzyme THAT STARTS THE RETINOIC ACID ALDH what is needed to produce ALDH ? acetyl-coA and a nad+ cofactor. two supplements that help with this... pantethine and b3 Alcohol dehydrogenase as a critical mediator of retinoic acid synthesis from vitamin A in the mouse embryo. Excessive vitamin A toxicity in mice genetically deficient in either alcohol dehydrogenase Adh1 or Adh3. Retinoic acid down-regulates aldehyde dehydrogenase and increases cytotoxicity of 4-hydroperoxycyclophosphamide and acetaldehyde.
  10. do NOT take accutane. it ruins some people forever. nothing is worse than joint pain and skin that wont heal.