I have had acne since I was 12 (I am 17 now), and nothing I have ever used has worked. Until this. I have a medium ammount of acne, and I usually get it around my jaw, my cheeks, around my eyebrows and around my lips. I got this prescribed at 100mg (1 pill) per day. It has only been 2 weeks and I can see some changes. My pimples have stopped growing for the most part, and all the redness of them has gone down a lot. I use it with prescribed topical once every night, and now my face just feels so soft and smooth. I do get minor side effects, such as some disiness, nausea and head aches, but I feel that they are very minor and tolerable, especially seeing how good it has done on my skin.