Have had mild-severe acne for about a year now. Went to a dermatologist who got my taking doxycycline tablets twice a day (as well as face cream) and told me to come back in a month if I hadn't noticed any changes. Face was dry/scaly for about a week and a half. After a month of taking them I noticed no changes. Not only did I have the same red scaring dots, I was still getting bumbs on my face (acne). So for me personally it did not work as I think they were not strong enough. He has now put me on Bactrim and Epiduo gel. Hopefully that works.