tanedout

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  1. Yeah I know what you're saying, and I'm aware it's a risk, but looking at it purely from the perspective of documented recoveries, there are at least 3 who have recovered via this method. Second to that would be RSO, which I've tried and was unsuccessful with (I couldn't get anywhere near the recommended dose), although this did show some glimpses of normality, but nothing lasting. The next things I'm going to try anyway are another go at methylation as I think I've increased my tolerance to methylfolate a fair bit now, and also trying to balance serotonin and dopamine through diet and supplements; http://www.withoutagym.net/dopamine-and-serotonin/
  2. This is great to hear, and really good that he's willing to offer up some advice, so I'll be really interested to see what he says! IMO the micro-dose finasteride route to re-sensitise receptors looks increasingly like the only way to really get out of this mess, but obviously if there are any alternatives that might have the same effect but are safer then these are going to be preferable of course.
  3. It's a shame the whole text isn't visible - it would be interesting to know specifically what RAR antagonists are being referred to here.
  4. Wow great to get a response from him - he doesn't elaborate on what these alternative methods might be though, did you respond to him and ask?
  5. But this sort of thinking is exactly the reason that people are still in this mess. Let's be brutally honest here - the side effects from accutane are basically permanent. There are people who've been in this mess 30+ years - I can think of a few on this thread who are around the 20 year mark. Coming up to 7 years for me. It's pretty clear that if your body was going to revert back to normal it would've done so by now. It's going to take more than a green leaf smoothie and crossed fingers to get out of this mess unfortunately. Maybe you are happy to live the rest of your life impotent, feeling brain dead, or with chronically dry skin, but even if you are we've got all the markers for being massively more susceptible to chronic diseases. It's absolutely not healthy for our bodies to be in this state. Ironically the micro-dose finasteride route comes from probably the only actual Doctor to have looked into this is depth (due to him himself being affected, so it was in his interest). And oh, he cured himself. Then so did at least 2 others using this method, so it should not be discounted. I'm not taking this option off the table, and if I try it it will be at my own risk.
  6. Did you see no benefits from the colostrum? What sort of amounts were you taking, over what period? I'm sure you're already eating a clean diet with little/no processed foods/fast food/sugar etc and plenty of steamed/raw vegetables plus healthy fats like salmon, mackerel, avocado, butter from grass fed cattle which your body will use to make hormones, but it might be worth adding in an active b-complex (I take 1/3 of a Jarrow B-right per day). If I was giving the dr Pezzi method a go I'd probably start on a really small amount of fin for a couple of weeks, then stop and gauge the benefits for a couple of weeks, then repeat. It might even be worth contacting Dr Pezzi himself - he was encouraging people with tane sides to contact him so he could record cases, but this goes back some years. Some of the links aren't working, but the contact him part appears to; http://www.erbook.net/accutane.htm
  7. Colostrum should contain Lactoferrin, which I posted was wiped out by isotretinoin. Does it say the amount? Lactoferrin is much more expensive then colostrum so it must not contain alot. But a therapeutic dose of Lactoferrin might be as little as 250mg. It's involved in a lot of sections throughout the body. Helps growth and establish the beneficial gut flora from birth. Also wipes bad bacteria and biofilms. Still curious about this one. Yeah Lactoferrin is something I've looked at in the past, and did order some although it never arrived and I didnt ever re-order. My gastrointestinal tests showed "no lactoferrin detected", but the result said this indicated "no active intestinal inflammation". I was a bit surprised at that, but even so plan to give colostrum a go at 20g/day for a couple of weeks, unless it causes me issues.
  8. That's interesting actually, as I've just got a load of Colostrum which I plan to work up to 20g/day on (starting from next week some time), basically to try and reduce gut inflammation (i've read some impressive stuff about people seeing huge improvements in gut issues from taking a high dose of high quality colostrum over periods even as short as a week or two). Colostrum has been noted to result in significant increases in IGF-1 in trials; https://www.ncbi.nlm.nih.gov/pubmed/12133885 https://www.ncbi.nlm.nih.gov/pubmed/18443138 The Dr Pezzi method has had me thinking too, and it also made me remember there was someone on this thread who recovered their Accutane sides from a low dose of propecia; http://www.acne.org/messageboard/topic/295030-repairing-the-long-term-damage-from-accutane/?page=198 There is also another guy on propeciahelp (GoldenW) who had success with this method. So that makes 3 people in total including Dr Pezzi. The only other convincing Accutane recoveries I know of are from taking RSO (cannabis oil), but also a few others (including myself) who haven't had success with that. It's just having the bottle to actually take a low dose of finasteride/propecia really, but I'm not discounting it (coming up to 7 years of being fcked over by tane)
  9. Anyone ever had their neurotransmitters tested?! I've had loads of blood tests like a lot of people here, but clearly the issues go beyond getting a perfect hormone panel, and it would appear neurotransmitters are out of whack too, but you can get these tested and work with a doctor to correct imbalances, depending on what those are. Obviously imbalances can lead to issues everyone is familiar with: http://www.heartspring.net/brain_improving_happy_balance.html Anyone had one of these tests? Anyone know if you can get them on the NHS without too much trouble? Not surprisingly the link above advises that good diet and exercise are important, but you can take supplements to boost certain neurotransmitters (obviously), however despite many of the supplements mentioned in the above link being familiar to people who follow this thread (I've tried most them in the article on and off), has anyone actually taken them in response to actually been tested and confirmed as having low GABA for example, rather than just the 'stab in the dark' approach?.. You could test, attempt to correct whatever is low by suggested sups, retest etc. The article also stresses that properly digested protein is critical to being able to create neurotransmitters properly, and with everyone clearly having gut issues to some degree it's not hard to see how this could be a problem. On that note I've actually only fairly recently started taking digestive enzymes with meals and have found this improves digestions significantly for me, so I'd highly recommend them (I used ones which contain Bromelain and papain). @MonsterDiesel - how much methylfolate are you able to take? I take an active B-complex (with some methylfolate included), and additional active B12 (Methylcobalamin), but I really can't tolerate much additional methylfolate - I get chest pains (seems to be a fairly common side effect). My 23andme does show I have 1/2 the MTHFR defect, but even so I'm surprised at how badly I tolerate it. Started this in response to this; http://howirecovered.com/active-b12-therapy-faq/ Rich Van K over on Phoenix Rising (chronic fatigue/ME forum) reckoned a high dose of methylfolate would make sense as a potential resolution to tane sides by down regulating GNMT, but I've not been able to get anywhere near the likely required dose to try this (I've tried various brands as well);. From Rich Van K: http://forums.phoenixrising.me/index.php?threads/roaccutane-caused-depression-isotretinoin.12117/#post-206039
  10. Just looking at that '8 tips for reversing accutane damage' video on youtube again, and there's loads of comments on it now, with quite a lot of information including some links to some recent studies, worth a look for anyone who hasn't seen it recently; https://www.youtube.com/watch?v=ZSwp10B44lg
  11. Read into GHK-Cu's action on retinoic acid receptors. GHK-cu could be really promising for our conditions if it's as effective at reducing inflammation as you feel it is. That guy who recovered from his PFS sides and put the PFSHealing site together reckons inflammation is the first thing to address before you can really start the healing process http://www.pfshealing.com/key-to-curing-post-finasteride-syndrome-inflammation/
  12. Anyone found LDN has had any positive effects on cognitive issues or libido??
  13. Following on from the recent discussions about Clomid, I see one guy on the AllThingsMale forum was apparently having some success using Clomid, followed by a stint on an AI (Aromasin) along with Pregnenolone; http://www.allthingsmale.com/community/threads/my-sitch-post-accutane-and-starting-to-recover.21372 Has anyone supplemented with Pregnenolone before? A lot of the PFS guys seem to get quite good results from it. It seems this stuff is absolutely destroyed by taking finasteride, so chances are it’s the same with accutane (note Pregnenolone is a pre-cursor to Allopregnenolone, just look at these figures) https://www.hairlosstalk.com/interact/attachments/before-and-after-treatment-with-finasteride-edit-png.16479/ http://articles.mercola.com/sites/articles/archive/2000/08/27/adrenals.aspx Well would be no surprise if our levels of pregnenolone were extremely low. My gastrointestinal tests showed cholesterol at non-detectable levels which was a surprise. The guy in the link above also has very low cholesterol, and I can think of at least one person on this thread whose had a blood test and found levels were very low. Why do you need Cholesterol? Few things here will ring a bell.. http://articles.mercola.com/sites/articles/archive/2014/04/14/vitamin-d-cholesterol-levels.aspx Pregnenolone is clearly a very important steroidal hormone, so if we’re deficient it’s not hard to see how it could lead to problems with the creation of other hormones, and brain fog; http://articles.mercola.com/sites/articles/archive/2000/08/27/adrenals.aspx Anyone had a neurosteroid test? Anyone supplemented with pregnenonlone before? I’ve tried it for a short period, but I’m going to add it in again seeing as I’ve got loads left. I’m already focusing on trying to increase my healthy cholesterol levels with loads of fatty/oily fish, avocado, flax seeds etc.
  14. I used that for a few months, and it resulted in some improvements, but nothing ground breaking and the improvements didn't last long after stopping. Wouldn't recommend it if I'm honest.
  15. No I don't either, but I'd consider trying other DHT inhibitors if there is a chance of getting some improvements. I forget who was cycling saw palmetto, but interested to hear if he got any gains.
  16. Have you tried the Dr Pezzi method of cycling another DHT inhibitor like finasteride to re-sensitise receptors? http://www.propeciahelp.com/forum/viewtopic.php?f=1&t=3310 http://www.erbook.net/accutane.htm Someone was trying this with Saw Palmetto? Any improvements?
  17. Found it - it was Dr Pezzi (doctor who cured his tane sides with Finasteride. Worth a re-read with a number of members having quite a good understanding now of potentially why this may have worked; http://www.allthingsmale.com/community/threads/official-accutane-thread.20097/page-30 @MTS & @HideAndSeek - I'd definitely focus on diets, minimal sugar and processed foods, lots of leafy greens, lean meats and oily fish like salmon etc. Dry/stiff joints sounds like low e.
  18. This was pretty much the method used by Dr Pressi? Prezi? (any old school members remember the name of this guy? Believe he wrote a book on recovering from his sides, but I can't remember the correct spelling of his name). He took a very small amount of finasteride over a course of months and made a full (albeit slow) recovery. I was trying to find info on the guy and his protocol (which I've read before). Anyone have the links? I feel sorry about you , kinda dark story. But what you mean by saying hopped on HGH ? im still 18 so i have my last chance to grow my height , do you mean is there any pills which boost growing ? do you mean growing hormone supplements ? also one last question ; is there any possibility that accutane caused me a low growing with only 4 days of usage ?? i still have low semen volume because of 4 days of usage. So , is it also could affect my height ? I read that Accutane kills the pituatry grand cells so the body can not send growing message , to the bones.. is it possible for me ? Interval training in a fasted state increased HGH by 2000% in men in one study. Might be worth at least doing intermittent fasting, or a series of short term water fasts if you want to increase HGH https://draxe.com/intermittent-fasting-benefits/
  19. @TrueJustice The test I took is this one from Genova Diagnostics. https://www.gdx.net/product/comprehensive-digestive-stool-analysis-with-parasitology-cdsap A lot of the PFS guys have taken the same one, and everyones has come back with indicators of poor gut health. One consistent thing is everyone tested (15+ results that I’ve seen, mainly from a thread on SolvePFS) has ‘No Growth’ for the Lactobacillus species of good bacteria. Here are part of my results Also it’s worth noting that for 8 months prior to that test I was taking a daily probiotic with that strain, but clearly it’s not helped. Since getting the results I really hit the gut health thing hard with various probiotics such as Prescript Assist, and for my lack of beneficial e-coli used Mutaflor (which has to be transported in a refrigerated container), along with L-glutamine powder, kefir milk, kefir water, coconut water kefir, sauerkraut, kombucha, green banana flour (source of resistant starch), gluten free, digestive enzymes and a couple of other things, but besides the kefir milk seemingly improving mental clarity (maybe down to it being a good source of active folate), I can’t say I noticed anything ground breaking, however I’m trying to stick with a number of these things (along with a diet avoiding refined sugars, processed foods, omega 6 fats) My tests also show some other strange things like no detected triglycerides and cholesterol. @Weltschmerz47 I did 60 days of nofap last year but didn’t notice much from it to be honest, and my DHT is high (very high, 50% over the top of the range), although it’s some time since i was last tested. Someone said they got a benefit from 90 days of nofap taking l-tyrosine and dl-phenylalanine, so I'm going try that as I've not used dl-phenylalanine before. (see post from iamme below); http://www.acne.org/messageboard/topic/295030-repairing-the-long-term-damage-from-accutane/?page=408 Just checked my 23andMe and for both those SNP’s I’m T and +/- for both Yeah Allthingsmale is dead, and the mods tend to be a bit heavy handed. I just look on this and swolesource which is excellent for info and CD is an active poster there, but I think it'll turn into propeciahelp before long as a lot of PFS posters on there now and they've now created a PFS subforum.
  20. https://uk.yahoo.com/news/news/appendix-may-not-useless-145752941.html Anyone else had their appendix out?!.. Had mine removed when I was 7! Maybe a factor why my gut bacteria isn't in great shape (as confirmed by gastrointestinal tests), and could be a reason why I was susceptible to suffering persistent sides from tane. Gut health, hormone balance, methylation - all interlinked.
  21. Might be worth supplementing with the suggested things in the phase 2 section of this restart (seeing as you're basically finishing phase 1) when you come off the Anastrozole http://increasemyt.com/hpta-restart/ Active B vit complex, active B12, D3, vit E, DHEA, pregnenolone etc
  22. I'm the same, my DHT is high. How do you respond to DHT inhibitors like zinc? I'm better for eating loads of pumpkin seeds which are a natural DHT inhibitor. I've recently tried to lower E2 by using sustain alpha, but it doesn't help me at all. I just got progressively weaker morning glory, and started to feel low e2 sides like increasing anxiety, I was getting bad fatigue and was generally starting to feel pretty shit. I've stopped using it, and now those things are improving again. Others however are seeing good benefits from this stuff. What were your other results from your hormone panel?
  23. Good spot, that threads worth keeping an eye on, some interesting points made on there!
  24. Seems some have high DHT and respond well to zinc, and things that are a good source of zinc (i.e. pumpkin seeds). I'm in this group. Others have low DHT and respond well to things that raise it, namely creatine. Not sure if you've had bloods done, but presumably you'd have low DHT. I've just got some sustain alpha so I'm going to see if that helps. It should raise LH and FSH (as it blocks E2), and I'm low with those and in turn lower SHBG (mine is high-ish), and that will increase free testosterone.
  25. @MrErdemDid you also get DHT by any chance? You'd almost certainly see benefits from Anastrozole or one of these pro hormone formulas thats got loads of reservatrol in like AndroHard or Sustain Alpha, these bring down E2 a lot, but you don't want to crush it or you'll end up with achy joints etc and have to wait for it to rise up, so I'd go slow with whatever you try.