I'm 28 with adult onset acne. I've taken doxycycline before (also in the tetracycline family), but minocycline has been much more effective. I realize it's not a long term solution, but it has worked to minimize the cystic acne that was flaring up. Unfortunately, I had pretty bad side effects. I started out with 100mg tabs twice daily and got horrible headaches, dizziness, eye pain, etc. The dose was adjusted to 100mg once daily and I still get headaches, but the dizziness is gone. Overall, I think it's a decent product to kick start a remission of acne before starting something like spirnolactone or accutane. It's affordable relatively easy to take.