I stopped getting sick with flu often once I quit eating gluten. However, the low-dose Naltrexone therapy has almost completely resolved the following issues for me, which have plagued me for many years: Waking up with a sore throat daily (from GERD which may be resolving), waking up stiff and sore muscles every morning, loose stools and irregular bowel movements, low energy, brain fog, generalized anxiety and depression. Oh, and and erections are rock hard for the first time in years (sorry for the graphic information). It's not necessarily a cure-all, but I think it helps normalize immune function, and to boost the body's functioning and overall health. You can obtain it online, through various international pharmacies, however the advantage of having a doctor prescribe for me was so he could monitor my success. Also it is free with my insurance. As I said before, I think getting the 50 mg pills of naltrexone, and then making your own LDN by dissolving them is the way to go...no fillers, no going back to the pharmacy every month, and you can adjust the doseage as you need. My doctor was not going to prescribe it, except that I joked that I would start shooting heroin and drinking alchohol like a fish and then come back to him for Naltrexone. I guess he realized that it was easy enough for him to prescribe Naltrexone for "alcohol use" (not abuse, because that can effect your life insurance down the line, etc.) and if I use it off label then he is absolved from responsibility. Here is how to make your own LDN: http://www.rivernewsdesk.com/2011/08/24/preparing-low-dose-naltrexone-at-home/ If you must obtain it online because your doctor won't prescribe, etc. here you go: https://www.riverpharmacy.ca/drug/naltrexone-naltima I should mention that I have been getting these great benefits by taking the lowest of the low dose recommendation (1.5 mg). At that rate, a 30 day supply of Naltrexone will last me almost 3 years (or 1000 days) of low-dose Naltrexone. The immune system seems to be implicated in the overall dynamic of post-Accutane damage. Other glandular cells beyond sebaceous may also be vulnerable to "shrinkage" from Accutane. Just a thought.