Melie87 replied to MH14's topic in Hormonal acneHey! It's Amelia! We talked a lot about a year ago during my Accutane treatment! I did spiro for 6 months before accutane and it made my skin much worse when I increased doses. At 25 mg I was perfectly fine my skin was glowing but going to 50mg ruined my skin . It has been 8 months since accutsne and I'm still breaking out , not as bad and for the most part clogged pores are gone. I am going on mino hopefully in the next few weeks to control hormonal breakout and only take intermittently. I have completely clearer my diet as well. acne is an on going fight.