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  1. I'm not a doctor but it sounds like you could be having an allergic reaction. Not sure why your derm wouldn't consider that since face flushing seems like a very plausible indicator of a reaction. You could also double check (with your derm or maybe with the pharmacist - not sure how it works in the UK) that there isn't a negative interaction with anything else you're taking. I've been on spiro for 3 years and have never experienced this.