I have been on Tri Sprintec (which is excellent for lack of insurance) for maybe 2 years. Thanks to this pill, my skin has dramatically improved. I had light-moderate acne and would get large, deep blemishes on my back. Now I only break out on my face when (and if) I happen to miss a pill or top using The Regimen, and my back is completely clear. This had also completely cleared my forehead. This in combination with The Treatment (2.5% BP) are my go to!