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About Gladiatoro

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  • Birthday 02/24/1970

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  • Gender Male
  • Location Canada
  • Interests Master Herbalist , data research , skiing , movies , AC/DC , UFC.


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  1. What was your sons dosage , it's important because it gives me an idea on dosage vs long term damage .
  2. CBD oil has benefits and you don't get high off it bonus.
  3. That's a typical dose , I would be careful with ingesting too much vitamin A or retinol , our bodies don't like either too much . Basically our whole system has been screwed over same goes with alcohol limit it , that's how I got rid of the severe lower back pain . That and I increased my lemon water intake .
  4. Yes it's stored in the body hence the side effects . Your are typically ACCUSTAINED.
  5. That totally explains why prolonged rubbing of the skin causes heart palpitations and dizziness. I remember reading once everything you try on it ( skin ) works better by some dumb derm , I say sure if you want to have a heart attack go for it. This also explains how some people have remission of acne for years . For me it did NOTHING still get mild acne lol... so what was the point of this poisoning , one derm said it appropriately , it's a controlled poisoning .
  6. You read that right more than 7000 law suits have been filed . And yes it lists pseudo tumor as a side effect.
  7. Accutane Side Effects A A What Is Accutane? Its Uses and InteractionsAccutane Side Effects Accutane is effective at controlling serious cases of acne, but it also comes with serious side effects like Crohn's disease and depression. Accutane was created by Roche Pharmaceuticals and approved by the U.S. Food and Drug Administration (FDA) in 1982. The drug is used to treat severe acne in people older than 12, and teenagers are its primary users. Treatment can last up to six months and may be repeated if acne returns. Unfortunately, Accutane is linked to a series of serious side effects, including bowel diseases like Crohn’s disease, liver damage, depression, and miscarriage and birth defects if taken during pregnancy. In fact, women of childbearing age are required to enlist in a special pregnancy prevention program before beginning Accutane treatment. Because of these injuries, more than 7,000 lawsuits have been filed against Roche Pharmaceuticals. Roche stopped making Accutane in 2009, but generic versions of Accutane, known as isotretinoin, are still available. Side Effects Doctors prescribe Accutane when other acne treatments fail. Because serious cases of acne can be such a physical and social burden, patients may be willing to tolerate some of the common side effects that come with Accutane use, including dry skin, headaches and cold-like symptoms. A less-common side effect of the drug is PSEUDO TUMOR – benign intercranial hypertension. This is a condition in which the brain acts as though there is a tumor when there is not. It can lead to blindness. Early signs of pseudotumor cerebri include headache, nausea, vomiting and visual disturbances. Birth Defects About half of Accutane users are women of childbearing age, making birth defects associated with Accutane use a significant concern. As of 2002 — the year generic Accutane was approved — the FDA had received reports of 172 babies born with a congenital defect or anomaly after maternal use of Accutane. From 1982 to 2006, more than 2,000 isotretinoin users became pregnant, resulting in many spontaneous or elective abortions. The pregnancy prevention programs initiated by Roche seek to educate patients about taking measures to ensure that women of child-bearing age do not become pregnant while taking Accutane and that they are aware of the risk of birth defects. However, these programs do not completely eliminate the occurrences of birth defects from Accutane. Roche has used the SMART program and the iPLEDGE program. The SMART program required patients to sign consent forms, watch informational videos, take a pregnancy test and use two forms of birth control. The program was not deemed effective, so in 2006 iPLEDGE was developed. This program required pregnancy tests from doctor’s offices and patient registration by computer. A study completed in 2011 on Kaiser Permanente, California health care patients revealed that iPLEDGE did not significantly decrease fetal exposure to Accutane. The rate of fetal exposure was similar with both programs — an average three exposures for every 1,000 patients. The type of fetal danger resulting from exposure to Accutane is alarming, ranging from causing miscarriages to babies born with slits where ears should be. Since 1985, Accutane has carried a black-box warning, the FDA’s most serious warning, detailing birth defect risks. The warning states: “Accutane must not be used by female patients who are or may become pregnant. There is an extremely high risk that severe birth defects will result if pregnancy occurs while taking Accutane in any amount.” The boxed warning also lists possible birth defects that could result from taking Accutane, including:Skull abnormalitiesEar abnormalities Facial dysmorphiaCleft palate Eye abnormalitiesCentral nervous system abnormalities Thymus gland abnormalityCardiovascular abnormality Parathyroid hormone deficiencyLower IQ Gastrointestinal Disorders Gastrointestinal disorders are characterized by intermittent symptoms and remission. The intestines can become inflamed and may be seriously damaged. Treatments vary based on the severity of symptoms and range from medication to bowel removal. There are two types of gastrointestinal disorders that Accutane has been linked to: Crohn’s disease and ulcerative colitis. Crohn’s and ulcerative colitis manifest themselves differently and affect different parts of the intestinal tract. They share some symptoms:Weight lossMalaise Abdominal painFever Rectal bleedingBloody diarrhea The number of cases of gastrointestinal disorders associated with Accutane use has continued to grow over the years. From 1997 to 2002, there were 85 cases of Inflammatory Bowel Disease (IBD) associated with isotretinoin use, but the exact connection was not confirmed. In 1999, The American Journal of Gastroenterology published a letter to the editor asserting a possible connection between isotretinoin and IBD. Another study published in the same journal in 2005 reviewed 85 cases of IBD and found that Accutane was a possible trigger for the disease. From 2003 to 2011, the FDA adverse event database received 266 cases of IBD associated with isotretinoin use. Crohn’s Disease Crohn’s is an autoimmune disorder, meaning that the body’s immune system attacks healthy body tissues. The disease often affects the small bowel and the beginning of the colon, but can also affect any part of the gastrointestinal tract. There is no cure for Crohn’s, but people may experience asymptomatic periods between flare-ups. People with severe cases of Crohn’s may experience pain and bleeding during bowel movements, caused tears in the lining of the anus. Other complications include abscesses, inflammation of joints, thickening of the intestinal wall, and possible surgery to remove the entire colon. Ulcerative Colitis Ulcerative Colitis (UC) often starts in the rectal area and progresses to the colon. The lining of the colon can become inflamed and develop ulcers that produce pus or mucous. Around half of people with UC experience milder symptoms, such as abdominal pain, blood and pus in stools, diarrhea, fever, rectal pain and weight loss. People with severe cases of UC often require hospitalization for acute attacks. Repeated attacks cause thickening of the intestinal wall and rectum from scar tissue, which can cause infections. Complications from UC include blood clots, colorectal cancer, massive bleeding, tears in the colon, liver disease, mouth sores and ulcers. The only cure is a removal of the colon. Liver Damage Some Accutane users have suffered from irreversible liver damage, which can lead to cirrhosis and require a liver transplant — a serious surgery that can be life-threatening. Due to this danger, liver enzyme tests are required prior to beginning Accutane and four weeks after treatment begins. Patients with a history of liver disease should not take this medication. Additionally, alcohol should be avoided during treatment to decrease the risk of liver damage. In addition to patient reports of liver damage, studies have documented a connection between Accutane and liver damage. In Roche’s clinical trials, 15 percent of patients treated with Accutane experienced inflammation of or damage to liver cells. In 2006, a research team at the University of California found that 11 percent of 13,772 Accutane patients tested had elevated liver enzymes. When enzymes are elevated, it can indicate that triglycerides and fats have accumulated in the liver, inflammation or that liver cells have died. Symptoms of liver damage include:FatigueUpper abdominal discomfort Fluid buildup in the abdomenSwelling of the liver Jaundice (yellow color in the skin) Depression and Suicide Many people have reported depression and suicidal behavior associated with Accutane. From 1982 to 2005, there were reports of 190 suicides by Accutane users. The FDA received so many reports that in 2003 Accutane was one of the top 10 drugs most often associated with depression and suicide attempts, according to the FDA’s database of adverse events. While some people who have acne already suffer from depression, there are many reports of depression from patients with no psychiatric history. Close surveillance of patients by physicians and friends and family can prevent depression symptoms from worsening and keep patients from harming themselves. Symptoms of depression to be aware of include:AnxietyCrying spells Loss of interest in activitiesSadness IrritabilityChanges in appetite Difficulty concentratingDifficulty sleeping Poor performance at work or schoolWithdrawal from friends or family Feelings of worthlessnessActing on dangerous thoughts HallucinationsThoughts about hurting or killing oneself Like I often say , the worlds MOST dangerous DRUG .
  8. I have already reported my most dangerous side effect possibly life threatening at times when it flairs up , yes it's pseudo tumor and as I have often mentioned it's a WELL documented side effect directly linked to accutane. FACT.
  9. "You know I've seen a lot of people walking around with tombstones in their eyes. But the pusher don't care if you live -- or you die. God damn the pusher man (written by Hoyt Axton, sung by Steppenwolf, 1969)." This is sadly the truth because in reality as I have found out after extensive research it's all LIES , the whole allopathic system is CORRUPT to the core. How can you sell a drug if you don't invent the illness first , that is the question . Standard treatment after isotretinoin therapy is SSRI's yeah more #$%ing drugs to treat the side effects of another drug lol... I really have to laugh now , but it's true .
  10. Why are you quoting one of my statements from another forum verbatim and linking it to a totally unrelated page on naturalnews? Why not , people like the info . And the unrelated page is actually related to our condition as we are all suffering from chronic cellular dehydration after isotretinoin exposure .
  11. I remember reading once from a very smart MD concerning isotretinoin he said and I quote " If you manage to recover from the devastating side effects of isotretinoin DON'T EVER go on it again. Key word IF you manage to recover.
  12. Not sure about fish oil retinol &);ed me over big time. A combination of beer and retinol.
  13. Dr. Bremner’s focus is on Accutane’s effect on the brain and it makes sense that he would not have much interest i n sexual side effects alone. Nevertheless, he is currently making a movie parodying his clash with Roche that is to be released in the next year: The Goose That Laid the Golden Egg. He is on our side and we can hopefully share a mutually beneficial alliance with him. When that movie comes out, it will give us an opportunity to make some noise again. Same with Dr. Healy. He is on our side. He believes those of us with sexual dysfunction from Accutane suffer from a form of PSSD, but can only do so much to help. He has done quite a bit to publicize the horrors of drug side effects and featured several stories about Accutane, Propecia, SSRIs, and Lupron on the RxISK site
  14. I have the same side effect pseudo tumor ,. It's a direct side effect of isotretinoin FACT.
  15. Exactly the drug should only be prescribed for people with severe nodular acne NOT kids young adults with a few pimples that's absolutely CRIMINAL.Acne Vulgaris: A Disease of Western Civilization
  16. You guys should try a supplement called alpha brain heared good things about it. Mainly UFC fighters use it . I would say say getting punched in the head often enough would eventually cause brain damage / trauma , due to MRI's we now know isotretinoin has similar effects on the brain.
  17. They hand this stuff out like CANDY to kids and young adults it's DISGUSTING , these people have absolutely NO idea of what they are getting into .
  18. Dosage and duration of chemo treatment?
  19. I seriously think I have a photographic memory years ago I read about this one derm in Australia he said and I quote " we don't know the long term outcome of these patients " I would say smart derm.
  20. You are typically ACCUSTAINED , dosage?
  21. I remember reading once , if you like to drink this is not the drug for you . In other words drinking alcohol after isotretinoin treatment is NOT recommended . Isotretinoin dries the hell out of you , alcohol also dehydrates so you have a double whammy . I can't believe I ever trusted allopathic medicine . If people want to cure there mild to severe acne cut out sugar and dairy .
  22. Page needing exploring about how accutane works and what else it's doing to you. I wish I could copy and paste the higher level board topics and their summaries. Topics like: " Significant Irriversible Hormone Antagonism" and "Affected neurotransmitters and parts of the brain". Unfortunately, in addition to some good content, there's a lot of placeholders and a hell of a lot of spam. What accutane does. Not light reading. Isotretinoin and FOX01 about FOX01 obviously, but also PPARy, IGF-1, Innate & aquired immune response, and many more mechanisms. including those that least to adverse affects like causing muscle pain, bone density, dry mucosa, hair loss, etc. ( I have the dry eyes/nasal passages (and mouth but it didn't mention mouth) and maybe the muscle ache. ) ) and hair loss. Linking diet to acne metabolomics, inflammation, and comedogenesis: an update Bodo C Melnik Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Germany Abstract: Acne vulgaris, an epidemic inflammatory skin disease of adolescence, is CLOSELY related to Western diet. Three major food classes that promote acne are: 1) hyperglycemic carbohydrates, 2) milk and dairy products, 3) saturated fats including trans-fats and deficient ω-3 polyunsaturated fatty acids (PUFAs). Diet-induced insulin/insulin-like growth factor (IGF-1)-signaling is superimposed on elevated IGF-1 levels during puberty, thereby unmasking the impact of aberrant nutrigenomics on sebaceous gland homeostasis. Western diet provides abundant branched-chain amino acids (BCAAs), glutamine, and palmitic acid. Insulin and IGF-1 suppress the activity of the metabolic transcription factor forkhead box O1 (FoxO1). Insulin, IGF-1, BCAAs, glutamine, and palmitate activate the nutrient-sensitive kinase mechanistic target of rapamycin complex 1 (mTORC1), the key regulator of anabolism and lipogenesis. FoxO1 is a negative coregulator of androgen receptor, peroxisome proliferator-activated receptor-γ (PPARγ), liver X receptor-α, and sterol response element binding protein-1c (SREBP-1c), crucial transcription factors of sebaceous lipogenesis. mTORC1 stimulates the expression of PPARγ and SREBP-1c, promoting sebum production. SREBP-1c upregulates stearoyl-CoA- and Δ6-desaturase, enhancing the proportion of monounsaturated fatty acids in sebum triglycerides. Diet-mediated aberrations in sebum quantity (hyperseborrhea) and composition (dysseborrhea) promote Propionibacterium acnes overgrowth and biofilm formation with overexpression of the virulence factor triglyceride lipase increasing follicular levels of free palmitate and oleate. Free palmitate functions as a “danger signal,” stimulating toll-like receptor-2-mediated inflammasome activation with interleukin-1β release, Th17 differentiation, and interleukin-17-mediated keratinocyte proliferation. Oleate stimulates P. acnes adhesion, keratinocyte proliferation, and comedogenesis via interleukin-1α release. Thus, diet-induced metabolomic alterations promote the visible sebofollicular inflammasomopathy acne vulgaris. Nutrition therapy of acne has to increase FoxO1 and to attenuate mTORC1/SREBP-1c signaling. Patients should balance total calorie uptake and restrict refined carbohydrates, milk, dairy protein supplements, saturated fats, and trans-fats. A paleolithic-like diet enriched in vegetables and fish is recommended. Plant-derived mTORC1 inhibitors and ω-3-PUFAs are promising dietary supplements supporting nutrition therapy of acne vulgaris. Keywords: acne, comedogenesis, diet, inflammasome, metabolomics, quorum sensing
  23. The big question every one wants to know , does isotretinoin cause depression , answer NOT necessarily he / she will have to live with reduced brain function for the rest of his / her life FACT. As as I have often stated derms LIE , MRI's DON'T.