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Is it possible to build a tolerance to BP over time? I know with other treatments I've been on such as Retin-A and minocycline, my skin built a tolerance to them overtime so they stopped working. I recently switched to Duac (5% BP, 1% clindamycin), do you think the same thing will happen with this treatment? Thank you!
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Building a tolerence to BP?
Started by CarSmithUGA, Jun 03 2005 09:26 AM
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#2
Dan
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Posted 03 June 2005 - 09:51 AM
It is physiologically impossible. P.Acnes bacteria can not survive in the presence of oxygen. BP creates oxygen.
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Niode
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Posted 03 June 2005 - 03:50 PM
I've wondered this as well.
Dave, you're probably right about the whole oxygen thing, but. . . I don't see why the human body can't figure out a way to counteract the effects of BP gel. I mean, sure, it's probably an unlikely scenario, but I wouldn't say it's physiologically and/or anatomically impossible.
Organisms are known to change certain aspects of themselves to accomodate change, correct? (i.e. developing callused skin as a result of continued pressure or friction, our bodies adjusting so our cells still receive sufficient oxygen when traveling to high altitudes, viruses becoming immune to antibiotics, etc.) Then why can't the body develope an immunity to BP gel?
(PS. Sorry to contradict you Dave, I have nothing against you or your regimin - in fact, I just started using it. I just had to speak my mind on this one.)
Dave, you're probably right about the whole oxygen thing, but. . . I don't see why the human body can't figure out a way to counteract the effects of BP gel. I mean, sure, it's probably an unlikely scenario, but I wouldn't say it's physiologically and/or anatomically impossible.
Organisms are known to change certain aspects of themselves to accomodate change, correct? (i.e. developing callused skin as a result of continued pressure or friction, our bodies adjusting so our cells still receive sufficient oxygen when traveling to high altitudes, viruses becoming immune to antibiotics, etc.) Then why can't the body develope an immunity to BP gel?
(PS. Sorry to contradict you Dave, I have nothing against you or your regimin - in fact, I just started using it. I just had to speak my mind on this one.)
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Dan
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Posted 04 June 2005 - 12:43 PM
From everything I have read in all of the medical literature, it is impossible for bacteria to become accustomed to benzoyl peroxide. Bacteria can develop a tolerance to antibiotics, but not to benzoyl peroxide. I am not a chemist, but I would think it's sorta like us somehow managing to live under water. It's just not gonna happen.
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Niode
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Posted 06 June 2005 - 08:48 AM
I hope you're right. The BP's worked wonders on lots of people, and I'm hoping it'll work for me, too.
If it weren't for the fact that bacteria are capable of mutating fairly quickly due to rapid cell reproduction, the thought of our bodies/bacteria adapting to BP wouldn't have even crossed my mind. But, with bacteria being the bunny rabbits of physiology, they can get around so to speak.
I just hope evolution keeps things slow with BP, however unlikely the scenario of immunity is.
PS. I'm not a chemist, either. Just a 17 year old kid with a bone to pick with evolution. Heh heh.
If it weren't for the fact that bacteria are capable of mutating fairly quickly due to rapid cell reproduction, the thought of our bodies/bacteria adapting to BP wouldn't have even crossed my mind. But, with bacteria being the bunny rabbits of physiology, they can get around so to speak.
I just hope evolution keeps things slow with BP, however unlikely the scenario of immunity is. PS. I'm not a chemist, either. Just a 17 year old kid with a bone to pick with evolution. Heh heh.
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