[QUOTE]Wrong. The reason people get acne when taking steroids is their lack of knowledge on what they are doing. If you keep the level of hormone in your system constant and even, you will have no problem at all. People break out when they have the hormone levels all over the place. Just another myth in the media, don't spread what you dont know.[/QUOTE]
Perhaps my statement was a bit general. But the concept is the same. The development of acne with steroid use and its extent depends largely upon the individual's constitution, the consumed steroids, and the dosage. The receptors of the sebaceous glands have a high affinity to DHT so that one must assume that steroids, which are partially transformed into DHT in the body, are the main cause.
This may also be the reason why the injectable testosterone, followed by Anadrol and Dianabol, are the number one cause of acne. With the increased sebaceous gland production oily skin occurs and, in combination with bacteria and dead skin, the pores become clogged. This can further, depending on one's disposition, lead to blackheads, pimples, pustules (filled with pus), or even cystes. Males experience the acne mainly on the back, shoulders and chest, less in the face, whereas female athletes are mainly affected in the face and on back and shoulder. Not only is there damage to the body's largest organ, the skin, but the noticeable acne is, even for an outsider, a distinct sign of steroid use.
Furthermore, it is laughable you would use the terms "injecting oneself with artifical hormones" and "constant and even hormone levels" in the same paragraph. I suppose you're one of those people who believe steroids are safe and its all a big conspiracy theory. Get real. Steroids are dangerous and the side effects are numerous, acne is one of them. Give me one study that shows scientific evidence that there is a safe way to take steroids and have no side effects. I'll save you time...there are zero. But there are thousands of legitimate scientific studies proving the reactions steroids will have on the body are unpredictable and that counteracting one drug with another drug is not "safe" or "balancing", its even more ignorant to believe a drug can counteract another drug and that is healthy and causes no side effects.
If you want to believe all these scientists are involved in a conspiracy, go ahead, but do not tell me I'm the one that is delusional.
Physical side effects:
Cancer...
Liver Damage...
Feminizing effects in males (growth of breast tissue)...
Male attributes in females (deepening of voice, excessive hair growth)...
Enlarged clitoris...
Shrunken testicles...
Limb loss...
Heart disease/heart attacks...
Physical addiction...
HIV/AIDS from the sharing of needles...
Reduced sperm count...
Impotence...
Infertility...
Baldness...
Pain and difficulty urinating...
Enlarged prostate...
Baldness...
Smaller Breast in women...
Menstrual cycle stops...
Adolescents experience premature closure of the growth plates (stunted growth)...
These are some of the physical side effects associated with steroid use. As you can see these drugs can affect the body in a very negative way. Despite all of these proven side effects people are still taking steroids. These side effects may not appear in all users at first. It is likely though with the long term usage of steroids that one or more of these side effects will occur in the user. These can be minor changes in the body and they can be extreme changes. It all depends on the dosage and duration of the usage. These are very good examples of why not to take steroids. Doctors are still discovering new side effects today, and there are still a lot of unknown problems with the newer more advanced steroids that will turn up. The trouble is people are taking steroids to look better and get stronger, faster, and quicker with no effort. What they are actually getting is a body that is like a time bomb waiting to explode. These drugs may help you look good for a short period of time, but they are also destroying the users body.
Physiological side effects
ROID RAGE (extreme uncontrollable aggression due to high levels of testosterone)
Irritability..
Aggressiveness...
Depression...
Mood swings...
Altered libido...
Psychosis...
Mental addiction...
These are the psychological side effects associated with steroid use. The use of steroids can lead to a persons whole personality changing. The users testosterone levels are at amazingly high levels-so high that they become a danger to themselves and others. Users of steroids have been known to pick fights for no reason, attack family members, and kill people. With the roid rages, changes in moods, depression, and psychosis users are mentally unstable. They can harm or kill themselves, and people around them. There have been many cases of suicide and homicide related to the use of steroids. These are the side effects that should concern people the most because this no longer just involves the users, but also the people around him.
H Bahia, A Platt, N B Hart, and P Baguley
Anabolic steroid accelerated multicompartment syndrome following trauma
Br. J. Sports Med., Aug 2000; 34: 308 - 309.
NA Evans
Local complications of self administered anabolic steroid injections
Br. J. Sports Med., Dec 1997; 31: 349 - 350.
[quote] In addition to the pharmacological side effects of anabolic steroids, complications may also result from the injection technique used in self administration. [/quote]
CJ Cooper, TD Noakes, T Dunne, MI Lambert, and K Rochford
A high prevalence of abnormal personality traits in chronic users of anabolic-androgenic steroids
Br. J. Sports Med., Sep 1996; 30: 246 - 250.
[quote] OBJECTIVE: (1) To assess the personality profiles of the anabolic androgenic steroid users (AAS) and (2) to determine whether valid premorbid personality traits could be obtained from cross sectional assessment using multisource data. METHODS: The first author became a participant-observer in a group of body builders. An experimental group of body builders who had been using AAS for no more than 18 months (n = 12) was identified. A group of control subjects, each of whom claimed that he did not, and never had, used AAS (n = 12) was also recruited during this period. Key informants played a crucial role in recruiting subjects representative of the AAS and body building communities. An interview schedule based on the Diagnostic and statistical manual of mental disorders (DSM3-R) personality disorder criteria was conducted with each subject. Additional data were obtained from an AAS using informant and significant others including family and friends. RESULTS: The user group was significantly heavier than the control group and showed abnormal personality traits, in contrast to the control group. Personality traits of AAS users before the onset of AAS use, assessed retrospectively, were not different from personality traits of control subjects. There were significant differences between the before and after personality traits in AAS user group. CONCLUSIONS: The results suggest (1) that AAS use is associated with significant disturbances in personality profile, and (2) that these personality disturbances are possibly the direct result of AAS use. [/quote]
AJ McBride, K Williamson, and T Petersen
Three cases of nalbuphine hydrochloride dependence associated with anabolic steroid use
Br. J. Sports Med., Mar 1996; 30: 69 - 70.
[quote] Three case reports are presented of nalbuphine hydrochloride dependence meeting DSM IIIR and ICD10 criteria for opioid dependence. Nalbuphine hydrochloride is being obtained from illicit sources and used by those using performance enhancing drugs. In some cases this leads to opioid dependence. There is a potential risks of crossover between the misuse of drugs of performance and the misuse of psychoactive drugs by injection. Further research into the dependence potential of nalbuphine and the extent of the crossover between steroid misuse and other psychoactive drug misuse is required. The legal status of nalbuphine should be reviewed in the light of its availability on the black market. [/quote]
BJ Freeman and GD Rooker
Spontaneous rupture of the anterior cruciate ligament after anabolic steroids
Br. J. Sports Med., Dec 1995; 29: 274 - 275.
[quote] Anabolic steroids remain popular among body builders and power athletes despite numerous warning about their side effects. A case of spontaneous rupture of the anterior cruciate ligament is reported in a bodybuilder taking steroids. There are many published reports of tendon rupture associated with steroid intake. [/quote]
RY Liow and S Tavares
Bilateral rupture of the quadriceps tendon associated with anabolic steroids
Br. J. Sports Med., Jun 1995; 29: 77 - 79.
HM Perry and GW Hughes
A case of affective disorder associated with the misuse of 'anabolic steroids'
Br. J. Sports Med., Dec 1992; 26: 219 - 220.
[quote] In the pursuit of gains in muscle size and strength, body-builders may mistakenly use illicit drugs believing them to be anabolic steroids. The case described illustrates the physical and psychological dangers of such behaviour. [/quote]
HM Perry, D Wright, and BN Littlepage
Dying to be big: a review of anabolic steroid use
Br. J. Sports Med., Dec 1992; 26: 259 - 261.
G McKillop, FC Ballantyne, W Borland, and D Ballantyne
Acute metabolic effects of exercise in bodybuilders using anabolic steroids
Br. J. Sports Med., Sep 1989; 23: 186 - 187.
[quote] Four male bodybuilders who had started taking anabolic steroids were monitored during exercise. Most metabolic indicators were similar to bodybuilders not taking steroids; i.e. metabolic acidosis with little change in glucose. [/quote]
B Harris, NJ Cook, RF Walker, GF Read, and D Riad-Fahmy
Salivary steroids and psychometric parameters in male marathon runners
Br. J. Sports Med., Jun 1989; 23: 89 - 93.
DJ DaCruz, M Geeson, MJ Allen, and I Phair
Achilles paratendonitis: an evaluation of steroid injection
Br. J. Sports Med., Jun 1988; 22: 64 - 65.
[quote] prospective, randomised, double-blind study of 28 patients presenting with Achilles paratendonitis was undertaken in order to evaluate the role of peritendonous injection of methy prednisolone acetate (Depo Medrone). At presentation patients were either administered peri- tendonous injection of 40 mgs of methyl prednisolone acetate suspended in 1 ml of 0.25% marcaine or 2 ml of 0.25% marcaine alone. Response was gauged by resolution of pain, tenderness and return to normal activity. Patients who failed to respond to initial treatment were crossed over to the other group at 12 weeks. All patients received standardised physiotherapy [/quote]
M Alen
Androgenic steroid effects on liver and red cells
Br. J. Sports Med., Mar 1985; 19: 15 - 20.
[quote] Haematological and hepatic effects of testosterone/anabolic steroid self-administration were investigated in five power athletes during 26 weeks of training. During steroid administration blood haematocrit had increased 9.6% (p less than .05) in the study group (n = 5), but not in the control group (n = 6). This erythropoietic phenomenon was supported by increased (p less than .05) RBC and unchanged MCV. Blood haemoglobin concentration did not change markedly and consequently MCHC level in the study group decreased significantly (p less than .001). Also the erythrocyte sedimentation rate decreased (p less than .05) in the study group. The mean values of serum alanine aminotransferase, alkaline phosphatase and gamma-glutamyltransferase were and remained within normal range in both groups, although those of the study group were higher. The mean values of serum aspartate aminotransferase exceeded the normal range (56 U/l, at highest) but this may be of muscular rather than hepatic origin because of the severe training. It can be concluded that erythropoiesis was stimulated and liver function mildly impaired due to sustained high-dose testosterone/anabolic steroid administration. [/quote]
S Solberg
Anabolic steroids and Norwegian weightlifters
Br. J. Sports Med., Sep 1982; 16: 169 - 171.
RJ Shephard, D Killinger, and T Fried
Responses to sustained use of anabolic steroid
Br. J. Sports Med., Dec 1977; 11: 170 - 173.
[quote] Description is given of six body-builders who had been taking Methandrostenolone (up to 20 mg/day in intermittent courses for a year or more). testosterone levels were low relative to laboratory standards and luteinizing hormone levels were also reduced - particularly in relation to testosterone concentrations. Abnormal liver function tests were seen in three of the six subjects, and one had mild diabetes with high serum cholesterol, triglycerides and uric acid. The weight gain of the group was not outstanding, and the only possible finding was a high haemoglobin and haematocrit in one of the six subjects.
[/quote]
V Wynn
Metabolic effects of anabolic steroids
Br. J. Sports Med., Jul 1975; 9: 60 - 64.
RA Harkness, BH Kilshaw, and BM Hobson
Effects of large doses of anabolic steroids
Br. J. Sports Med., Jul 1975; 9: 70 - 73.
GR Hervey
Are athletes wrong about anabolic steroids?
Br. J. Sports Med., Jul 1975; 9: 74 - 77.
Alexander Mitchell and Veronica O'Keane
Steroids and depression
BMJ, Jan 1998; 316: 244 - 245.
[quote] The unwanted behavioural effects of anabolic steroids are widely known, but those of glucocorticoid therapy, though recognised for over 45 years, receive less attention. Placebo controlled studies have reported that a third of patients taking glucocorticoids experience significant mood disturbance and sleep disruption.1 More importantly, up to 20% of patients on high dose glucocorticoids report psychiatric disorders including depression, mania, psychosis, or a mixed affective state.2 A recent double blind placebo controlled trial of corticosteroid administration in healthy individuals showed that 75% of subjects developed disturbances in mood and cognition, which reversed when steroids were stopped.3 We do not know the characteristics of those who are vulnerable to adverse effects, but those with higher cumulative dosages appear to be most at risk.
Dysregulation of the hypothalamo-pituitary adrenal axis in depression is one of the oldest and most consistent findings in biological psychiatry. A large scale meta-analysis of over 140 studies using the low dose dexamethasone suppression test illustrated that persistent adrenocortical hyperactivity is a robust indicator of poor prognosis and a weaker predictor of suicide in depression.4 From the physicians' view point, medical disorders which feature sustained overdrive of the hypothalamo-pituitary axis carry an unexpectedly high risk of mood disorders. Patients with Cushing's disease, stroke, or chronic alcoholism, and those taking long term steroid treatment have a reported prevalence of depression above 50%.5 The precipitation of dysregulation of the hypothalamo-pituitary axis by environmental stressors may be important in the onset of both Cushing's disease and depression.6 However, not all increases in adrenocortical activity are associated with pathological consequences, and, as the core mediator of the neuroendocrine stress response, an acute failure of activation of the hypothalamo-pituitary axis is equally hazardous in animal and man. In fact, underactivity of the axis may be associated with a range of psychiatric disorders, the most extensively investigated being post-traumatic stress disorder.7
[/quote]
Thomas M. Jenkins, Ronald J. Wapner, Elizabeth A. Thom, Anita F. Das, Catherine Y. Spong, Kellie E. Murphy, Mary Hannah, Peter Brocklehurst, Julian L. Ambrus, Clara M. Ambrus, Debra A. Guinn, M. Wendy Atkinson, Lisa Sullivan, MenJean Lee, Scott McGregor, Barbara V. Parilla, Jill Davies, Kathleen Hanlon-Lundberg, Lynn Simpson, Joanne Stone, Deborah Wing, Keith Ogasawara, and Jonathon Muraskas
Are Weekly Courses of Antenatal Steroids Beneficial or Dangerous?
JAMA 2002 287: 187-190.
Joan Stephenson
Curbing Teen Steroid Use
JAMA 2000 283: 2514-b
L. Goldberg
Adverse effects of anabolic steroids
JAMA 1996 276: 257
D. H. Catlin and T. H. Murray
Performance-enhancing drugs, fair competition, and Olympic sport
JAMA 1996 276: 231-237.
E. M. Kouri, H. G. Pope, Jr, and D. L. Katz
Use of anabolic-androgenic steroids: we are talking prevalence rates
JAMA 1994 271: 347b
C. E. Yesalis, N. J. Kennedy, A. N. Kopstein, and M. S. Bahrke
Anabolic-androgenic steroid use in the United States
JAMA 1993 270: 1217-1221.
[quote]Among 12- to 34-year-olds, AAS use was significantly and positively associated with the use of other illicit drugs (P < .05), cigarettes (12- to 17-year-olds only; P < .01), and alcohol (P < .01). Furthermore, AAS use is highly correlated with self-reported aggressive behavior (P < .01) and crimes against property (P < .01). CONCLUSIONS--These results indicate that AAS use impacts a large number of men and women from various racial and age groups across the nation. While causal inferences cannot be made regarding the associations between AAS use and use of other drugs as well as antisocial behavior, these findings should enhance our ability to profile the typical AAS user.
[/quote]
T. P. Su, M. Pagliaro, P. J. Schmidt, D. Pickar, O. Wolkowitz, and D. R. Rubinow
Neuropsychiatric effects of anabolic steroids in male normal volunteers
JAMA 1993 269: 2760-2764.
[quote] OBJECTIVE--To evaluate the acute effects of anabolic steroids on mood and behavior in male normal volunteers. DESIGN--A 2-week, double-blind (subject and rater), fixed-order, placebo-controlled crossover trial of methyltestosterone. SETTING--An inpatient research unit at the National Institutes of Health. SUBJECTS--A volunteer sample of 20 men who were medication free, free of medical and psychiatric illness, not involved in athletic training, and had no prior history of anabolic steroid use. INTERVENTION--A sequential trial for 3 days each of the following four drug conditions: placebo baseline, low-dose methyltestosterone (40 mg/d), high-dose methyltestosterone (240 mg/d), and placebo withdrawal. MAIN OUTCOME MEASURES--Mood and behavioral ratings were completed during each drug condition and included both subjective and objective measures. RESULTS--Significant (P < .05) albeit subtle increases in symptom scores were observed during high-dose methyltestosterone administration compared with baseline in positive mood (euphoria, energy, and sexual arousal), negative mood (irritability, mood swings, violent feelings, and hostility), and cognitive impairment (distractibility, forgetfulness, and confusion). An acute manic episode was observed in one of the 20 subjects, representing a 5% incidence, even under these conservative conditions. An additional subject became hypomanic. Baseline characteristics including family psychiatric history or previous drug abuse did not predict symptom changes. CONCLUSION--This is the first placebo-controlled prospective study demonstrating the adverse and activating mood and behavioral effects of anabolic steroids.
[/quote]
K. B. Kashkin and H. D. Kleber
Hooked on hormones? An anabolic steroid addiction hypothesis
JAMA 1989 262: 3166-3170.
[quote] Widespread illicit anabolic steroid use has recently been reported. A review of available evidence suggests that elevations of serum levels of steroid hormones, including anabolic steroids, have profound psychological effects. Long-term, high-dose anabolic steroid use may lead to a preoccupation with drug use, difficulty stopping despite psychological side effects, and drug craving. Reductions in serum levels of steroid hormones appear to result in acute hyperadrenergic withdrawal symptoms that respond to steroid replacement or to agents that also ameliorate withdrawal symptoms in alcohol and opioid dependence. A delayed depression syndrome when serum steroid levels drop precipitously has been reported that appears similar to that observed in withdrawing cocaine-dependent individuals. We conclude that a proportion of anabolic steroid abusers may develop a previously unrecognized sex steroid hormone-dependence disorder and that treatment should be based on research into steroid effects on opioid and aminergic neurotransmission systems and relapse prevention. [/quote]
V. S. Cowart
If youngsters overdose with anabolic steroids, what's the cost anatomically and otherwise?
JAMA 1989 261: 1856-1857.
W. V. Moore
Anabolic steroid use in adolescence
JAMA 1988 260: 3484-3486.
W. E. Buckley, C. E. Yesalis, 3rd, K. E. Friedl, W. A. Anderson, A. L. Streit, and J. E. Wright
Estimated prevalence of anabolic steroid use among male high school seniors
JAMA 1988 260: 3441-3445.
Drug abuse in athletes. Anabolic steroids and human growth hormone. Council on Scientific Affairs
JAMA 1988 259: 1703-1705.
P. S. Salva
Anabolic steroids and sports
JAMA 1987 258: 1608b
R. H. Strauss, M. T. Liggett, and R. R. Lanese
Anabolic steroid use and perceived effects in ten weight-trained women athletes
JAMA 1985 253: 2871-2873.
M. A. Frankle, G. J. Cicero, and J. Payne
Use of androgenic anabolic steroids by athletes
JAMA 1984 252: 482b
D. A. Johnson
Use of anabolic steroids by athletes
JAMA 1984 251: 1430-1431.
M. G. Robertson
Postural hypotension and steroids
JAMA 1971 216: 1201b
R. W. Schrier and R. J. Bulger
Steroid-induced pancreatitis
JAMA 1965 194: 564-565.
The studies speak for themselves. The science is irrifutable - steroids are dangerous and a clear side effect is acne.
You logic is take a drug to counteract another drug? That's like saying I smoke pot to get rid of a hangover. Come on.
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If muscle cells are more sensitive to the effects of insulin your body does not need to release as much after a meal, in order to carry nutrients to your cells. The more insulin resistant your muscle cells are, the more insulin your body will release from its pancreas to promote storage of nutrients in them.
am i the only one that powerlifts anymore?
