Jump to content

New Antimicrobial Peptide Could Be an Excellent Therapeutic Agent for Acne Vulgaris


  • Please log in to reply
1 reply to this topic

#1 VanceAstro

VanceAstro

    Member

  • Members
  • Posts & Likes
    Posts: 119
    Likes: 1
About Me
  • Gender:Male
  • Joined: 31-December 10

Posted 02 August 2011 - 11:52 AM

Cathelicidins are a family of antimicrobial peptides acting as multifunctional effector molecules in innate immunity. Cathelicidin-BF has been purified from the snake venoms of Bungarus fasciatus and it is the first identified cathelicidin antimicrobial peptide in reptiles. In this study, cathelicidin-BF was found exerting strong antibacterial activities against Propionibacterium acnes. Its minimal inhibitory concentration against two strains of P. acnes was 4.7 µg/ml. Cathelicidin-BF also effectively killed other microorganisms including Staphylococcus epidermidis, which was possible pathogen for acne vulgaris. Cathelicidin-BF significantly inhibited pro-inflammatory factors secretion in human monocytic cells and P. acnes-induced O(2) (.-) production of human HaCaT keratinocyte cells.


Source: http://www.ncbi.nlm.nih.gov/pubmed/21789223

Edited by VanceAstro, 02 August 2011 - 11:53 AM.


#2 Empty Inside

Empty Inside

    Junior Member

  • Members
  • Posts & Likes
    Posts: 91
    Likes: 8
About Me
  • Joined: 09-August 10

Posted 12 August 2011 - 09:21 AM

sounds promising, do you know when it will be available?




0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users

Jump to... Go to top
Hello, Guest.
It looks like you didn't set up an avatar.
Do you want to set up an avatar now?
Let's do it!
refresh page when finished
     Remind me in a few days