Ooohhh Panoxyl..i've had some trouble with this stuff but I still use it. I started the Regimen using the full amount, having used Duac which is a higher percentage of BP before i thought i'd be fine!. Spent a whole day with my head wrapped in bandages and my face slathered in E45 until basically all my skin peeled off...which was nice.
i had some success in limiting the irritation caused by Panoxyl 2.5. I just changed my cleanser to one by Lush it's called Ultra Bland it's very non irritating and just has a peanut oil base you just smear it on and wipe it off gently with damp cotton wool.
My skin is spot free at the moment having recently experienced huge success with the regimen. However i've found myself buying a tube of Panoxyl a week and over the space of 2 months I'm spending 30 quid on it which I've worked out is the same cost as ordering some of Dan's 16oz peroxide which is apparantly far superior and less irritating. Ordered me some today If I can make it last 2 months then it'll be a worthy investment