62 replies to this topic

[radikal]

Sana Fela http://www.sanafela.com/ has started shipping its Nobiletin based anti-sebum cream!
Sadly shipping is US only so I can't test it myself soon enough! will someone based in the US please try it out and report back.

[Dwight]

I vote for that, please somebody try that stuff and report here. Wrote them an email asking for international shipment, they didnt wrote back
Anyone got an idea how to get that stuff to europe? Are there services which forward packets from .US to .EU?

[radikal]

I've set up a mailbox with shipito.com and had them ship to that. My parcel is already on its way to Europe.

[Densha504]

I ordered mines on thursday and it shipped this morning. I received an email saying it will arrive in 3 business days. For 12$ its worth a shot. I'll report back in a couple of weeks.

[Densha504]

I just got it in. The cream absorbs nicely and smells orangy. Once I have results Ill post about it.

[{DC}]

So basically its just tangerine essential Oil?

And radikal, how did you find out about this product. Reading their website it sounds like they actually have something that will work, unlike the other crappy supposed sebum reducing products out there.

Edited by {DC}, 27 December 2009 - 06:45 AM.

[silently_suffering]

Can we get an update from those who are trying this product??
PLEASE!!

[radikal]

So basically its just tangerine essential Oil?

And radikal, how did you find out about this product. Reading their website it sounds like they actually have something that will work, unlike the other crappy supposed sebum reducing products out there.

Look up this thread in the Research forum:
http://www.acne.org/messageboard/favourite...et-t243645.html

[jojo99]

Can we get an update from those who are trying this product??
PLEASE!!

OK, here are first impressions ---
I received the tangerine anti-shine cream a week ago and have been using it once a night before going to bed after washing with soap and cold water. It absorbs really quick and smells a little orangy, quite nice. I can definitely see a difference on my forehead. It is more "matte" than it used to be. I'd say so far so good. I hope that the results will improve further. The cream spreads very easily and you are only supposed to use a little. I think the jar will last about a month.

I am happy so far. I will post again in a few weeks and hope for further progress.
Has anybody else been testing too?

Looks like they no longer offer free shipping though...

Good luck and Happy New Year everybody!

jojo

[mbbento]

Does anyone know if you can use it with other products at night? Just asking, because I also apply Retin-A in the evening before I go to bed and wouldn't want to have to choose.

[{DC}]

I dont think you would have to choose. They recommend applying it at night, but I cant see why you couldnt apply it in the day time and keep using retin-A at night.

[Sanafela]

Sana Fela has started shipping its Nobiletin based anti-sebum cream!
Sadly shipping is US only so I can't test it myself soon enough! will someone based in the US please try it out and report back.

International shipping is now available!

[Ind1g0]

Not good The cream is probably not good for your skin. It's natural to produce sebum, its actually necessary for the function of your epidermis. To stop it from producing sebum- even playing with the skins natural oil production is never good. Try balancing skins PH rather than this.

[{DC}]

Not good The cream is probably not good for your skin. It's natural to produce sebum, its actually necessary for the function of your epidermis. To stop it from producing sebum- even playing with the skins natural oil production is never good. Try balancing skins PH rather than this.

This is a highly ignorant post. Please refrain from speaking on things you clearly have no to little knowledge on.

If this stuff works it will be a godsend.

Overactive sebaceous glands IS not a good thing for anyone. It makes skin uncomfortable and dirty feeling. Plus for those of us who have a keratinization problem this just adds insult to injury.

Sebum IS NOT needed for nice healthy skin. Look at little prepubertal childrens kin...its more beutiful than any. There sebum production if so little its insignificant. My skin used to be like that right up until 18-19. My skin was grwat. It was only when the sebum increased things went pear shaped with my skin.

Sebum doesnt eqaute to moisture for your skin.
It doesnt stop wrinkles.
It doesnt prevent your skin from drying out.

Accutane dries your skin out for reason outside of sebum production whcih I dont really have time to get into right now, but if you search this site I and Im sure others have posted about it.

Dont be scared of this product just be scared if it doesnt work.

Edited by {DC}, 02 January 2010 - 10:41 PM.

[{DC}]

Sana Fela has started shipping its Nobiletin based anti-sebum cream!
Sadly shipping is US only so I can't test it myself soon enough! will someone based in the US please try it out and report back.

International shipping is now available!

SWEET Sanafela!!!

Gonna try some out. Thanks for posting!

Edited by {DC}, 02 January 2010 - 10:45 PM.

[{DC}]

To what degree can one expect their sebum to be reduced by?

[radikal]

To what degree can one expect their sebum to be reduced by?

More to the point, is there a proportion between quantity of Nobiletin and subjective/objective sebum decrease?
To SanaFela: have you looked at this in your trials? would formulations with different active%/vol make sense?

The sebum excretion rates will vary substantially from one person to another.

[Ind1g0]

Not good The cream is probably not good for your skin. It's natural to produce sebum, its actually necessary for the function of your epidermis. To stop it from producing sebum- even playing with the skins natural oil production is never good. Try balancing skins PH rather than this.

This is a highly ignorant post. Please refrain from speaking on things you clearly have no to little knowledge on.

If this stuff works it will be a godsend.

Overactive sebaceous glands IS not a good thing for anyone. It makes skin uncomfortable and dirty feeling. Plus for those of us who have a keratinization problem this just adds insult to injury.

Sebum IS NOT needed for nice healthy skin. Look at little prepubertal childrens kin...its more beutiful than any. There sebum production if so little its insignificant. My skin used to be like that right up until 18-19. My skin was grwat. It was only when the sebum increased things went pear shaped with my skin.

Sebum doesnt eqaute to moisture for your skin.
It doesnt stop wrinkles.
It doesnt prevent your skin from drying out.

Accutane dries your skin out for reason outside of sebum production whcih I dont really have time to get into right now, but if you search this site I and Im sure others have posted about it.

Dont be scared of this product just be scared if it doesnt work.

Firstly, don't use the word 'ignorant' when you yourself don't seem to fully understand sebum. Secondly, don't use the word ignorant when you misspelled half of your post. I don't appreciate your rudeness. I am free to express my opinion, and it stands still. Do a little research on the internet if you disagree as strongly as you seem to. Lastly, I don't take accutane, and I didn't even mention accutane.

To everyone else: I am not arguing that overactive sebum production is not a bad thing. That is obvious. Too much sebum clogs pores! But a BALANCE of sebum is absolutely necessary for healthy skin! Everyone's skin produces it- it is a natural thing. Just to let you know, it is primarily the hormones that change during puberty. To use the skin of children as an example is wrong. Increased sebum production and the change of the skin's PH are factors that go along with the process. I am just warning you....the damage to my skin has been done because of all the products I've used. I've upset its delicate balance, and I'm paying for it. Here is an informative bit on sebum, to enlighten you:

"While sebum is usually looked at as a curse or a bad thing, sebum can actually be a helpful thing in the right amounts to the skin. It is only harmful in excessive amounts and when it begins to become hard and clog the pores. But if you have excessive amounts, obviously, you don’t look at it as a good thing at all, which is why some processes that dry out the skin have been so popular. Many believe that sebum is the only culprit for acne and it should be completely attacked and gotten rid of.

Sebum, in its right amounts, is actually responsible for your skin’s moisture and supple feeling in many cases. It can also protect skin from the bacteria and fungi that can cause skin damage in general as well as acne. It has even been said to reduce body odor and protect the immune system from major damage. It is found in literally every follicle and pore in the body, and it surrounds hair to keep everything in working order.

But bacteria is a greater culprit for acne than is sebum. It traps sebum so that it becomes hard in the pores, and it causes ultimately blackheads, future acne, and other problems. You should definitely clean your skin on a regular basis to keep excess sebum at bay as well as to kill of bacteria that may trap it. But you should be careful and regulate the amount to which you regulate the oils. Just remember that it is a good thing and a necessary thing in the right amounts."

So, to sum up: BALANCE IS KEY GUYS! Please read...

[{DC}]

Firstly, don't use the word 'ignorant' when you yourself don't seem to fully understand sebum. Secondly, don't use the word ignorant when you misspelled half of your post. I don't appreciate your rudeness. I am free to express my opinion, and it stands still. Do a little research on the internet if you disagree as strongly as you seem to. Lastly, I don't take accutane, and I didn't even mention accutane.

Seriously dude you really have no clue do you??? You are the one who doesnt understand sebum nor acne. And yes I will use the word ignorant because that is what you clearly are. Ignorant isnt necessarily a bad thing it just means you lack knowledge on a certain subject, in this case sebum and acne!

You are free to your opinion, but without any scientific evidence what you wrote is just that...one persons opinion completely devoid of any evidence. It can never be accepted as factual or truth in this setting.

And I re-read my post and there are no spelling errors, just a few obvious typos(there is a difference you know) stop being such a Nazi with the typos. But since you really have no science behind your argument no wonder you try and fault my typos, thats all youve got.

LOL at "do a little research on the internet". Thats all you seem to have done obviously. There is SO much erroneous information on the internet its ridiculous. You didnt even bother to reference who wrote that "informative bit" you posted. Which is mostly garbage by the way.

the damage to my skin has been done because of all the products I've used. I've upset its delicate balance, and I'm paying for it.

You have obviously used harsh products, which no matter how harsh they were WILL NOT reduce sebum. Unless they had antiandrogens in them, which I doubt they did. Your skin being ruined has nothing to do with your sebum or lack thereof. You have just abused your skin with harsh products and stripped it of its moisture content. Sebum doesnt keep you skin moist, things like ceramides, fatty acids and cholesterol(the lipid bilayer) do. Water holding proteins and sugars such as the proteoglycans and glycosaminoglycans also help hold water in the skin.

You can over wash your skin and use harsh products and be an oil slick in 1 hour again, yet your skin will still be tight and dry. Many people often say how their skin is dry yet oily at the same time. If what your claiming is correct how is that possible? Those people have chemically dried out their skin, yet their oil glands are still churning the sebum out regardless. Which leads to a dry, oily mess. Sebum will mask dryness/slight flakiness though because its an oily substance.

Sebum, in its right amounts, is actually responsible for your skin’s moisture and supple feeling in many cases.

WRONG! Here is what one of the most renowned dermatologists there is in Kligman has to say on the matter:

Journal of Investigative Dermatology. 1987 Mar;88(3 Suppl):2s-6s.
"Skin lipids: an update"
Downing DT, Stewart ME, Wertz PW, Colton SW, Abraham W, Strauss JS.

Sebum and Dry Skin "...skin can be healthy and have charming cosmetic properties in the virtual absence of sebum."(14)

Kligman drew attention to prepubertal children, who produce almost no sebum, to support his thesis that skin does not depend upon sebum for maintaining its barrier to water loss: "...there can be no doubt of the insignificance of sebum as a waterproofing material."(14) Our recent studies at the other end of the human age spectrum have supported this conviction. In a survey of sebum secretion rates and the incidence of dry skin among subjects aged 65 to 97, no correlation was found between sebaceous gland activity and the presence or severity of dry skin(34). Kligman recognized that sebum could mask the scaliness of dry skin without producing any actual change in the condition: "Sebum, like any oil, has some emollient or smoothing effect when a sufficient quantity is rubbed into dry, scaling skin."(14) In spite of the clear inference to be drawn from the cutaneous characteristics of children and the experimental data obtained from the elderly, it remains difficult to dispel the myth that low sebum secretion rates cause dry skin. It is a rare individual who realizes that "dry" is not the obverse of "oily".

(14) Kligman AM: The uses of sebum. Br J Dermatol 75: 307-319, 1963

(34) Frantz RA, Kinney CK, Downing DT: A study of skin dryness in the elderly. Nursing Res 35: 98-100, 1986.

But bacteria is a greater culprit for acne than is sebum. It traps sebum so that it becomes hard in the pores,

What nonsense is this you have quoted?! Honestly where are you citing this garbage from? Bacteria doesnt trap sebum, its the other way around. Dead skin cells and sebum create a blockage of the pore. P.acnes bacteria gets trapped in there. P.acnes feeds on sebum and can thrive in this oxygen free environment. When it feeds on the sebum it releases a certain chemical that irritates the skin, which in turn sends out an immune response which leads to puss and inflammation.

Bacteria is way down the pecking order in regards to the pathogenesis of acne. EVERYONE has p.acnes on there skin yet not everyone has acne.

Just remember that it is a good thing and a necessary thing in the right amounts."

You have yet to prove that at all. That informative bit was tripe and you didnt even cite where it came from. Your mother could have been the source for all I know.

So, to sum up: BALANCE IS KEY GUYS! Please read...

This may sound rude, but to sum it all up, you are the one in need of research(quality research I may add). Not just pulling some arbitrary quote off the net and telling people that sebum is absolutely necessary just because you raped your skin with harsh chemicals. So you please read...

And please cite who you quoted for that so called informative piece. I would love to know where you got it from and who wrote it.

Edited by {DC}, 03 January 2010 - 02:43 PM.

[bryan]

To everyone else: I am not arguing that overactive sebum production is not a bad thing. That is obvious. Too much sebum clogs pores! But a BALANCE of sebum is absolutely necessary for healthy skin!

The poster {DC} has already answered your post very well, but I can't resist adding one or two minor comments of my own: please cite some evidence that shows that sebum is "absolutely necessary for healthy skin". I'd be intrigued to read anything at all about such a claim (with the only stipulation being that it's from a scientific source, of course).

Everyone's skin produces it- it is a natural thing.

Really? The palms of your hands don't even HAVE any sebaceous glands, so they don't even make sebum AT ALL. Is there anything really bad and unhealthy about the skin on the palms of your hands? No? Then why do they seem to do just fine without any sebum at all?

To use the skin of children as an example is wrong.

Why is that? Why is it "wrong" to use the skin of children as an example?

Edited by bryan, 03 January 2010 - 04:43 PM.