1150 replies to this topic

[halfpipe101]

Lamar im thinking about going on doxycycline for 4 or so months

thoughts would be great

although my flushing has decreased

my overall skin is not doing good..redness..mild acne,roughness

I was wondering whats ur thoughts on this and if its a good idea or not

and what dose would be the best 50 mg 75 mg 100 mg

and as far as i know doxy cant make flushing worse like accutane as they are not the same family

Edited by halfpipe101, 29 September 2009 - 03:37 AM.

[jordan1234]

JT, thanks for responding that's interesting. Does anyone else have an issue with not sweating?

[oli girl]

JT, thanks for responding that's interesting. Does anyone else have an issue with not sweating?

Uhm, I have checked regarding accutane and lack of sweat...I don't doubt that Accutane can cause this. I still searching for info on this.
I am not sure of all your problems or why your on the HgH, but Lack of sweating is called Anhidrosis It's main causes are from medications, dehydration, damge to the sweat glands, skin damage to the skin (blood vessels,nerves surrounding the blood vessels)

certian medical conditions such as people with Sjogren's, thyroid, other hormonal diseases (disruption of the pitutary and hypothalmus) and people with autonomic disorders experince lack of flushing or the oppisite excessive sweating.
Well alot people who are poisioned by Accutane experince alot of theese things.

As for lack of sweating and flushing- What I have read people who can't sweat need to loose body heat so they tend to flush to release the heat.

Alot of people who have taken Accutane have reported temp regulation problems, so basically you skin and body can no longer thermoregulate.

Seattle-I spoke with Jame O'donnell Ph.D. from the Congressional hearings on Accutane recently, I'll PM you soon on that.

Edited by oli girl, 01 October 2009 - 07:33 AM.

[jordan1234]

oli girl, thanks you the info. Other than taking GH to help speed up the regrowth of cells that have been damaged and/or repair pituitary dehydration, how does one fix the sweating issue. The subcutaneous layer of the skin seems to be damaged, which as you said said includes nerves, subcutaneous glads, and blood vessels. There must be a way to target the problem and ultimately resolves it.

[oli girl]

oli girl, thanks you the info. Other than taking GH to help speed up the regrowth of cells that have been damaged and/or repair pituitary dehydration, how does one fix the sweating issue. The subcutaneous layer of the skin seems to be damaged, which as you said said includes nerves, subcutaneous glads, and blood vessels. There must be a way to target the problem and ultimately resolves it.

Well, If your skin,nerves etc are permanently damaged then no there really isn't any treatment...from what I have read repeatedly.... stem cells????????????

If it is caused by hormonal such as pituitary/thyroid fixing thoose problems should help.
If it is autonomic problem then doing your best to thermoregulate your temp would help some.

I did read that for some who have sweat gland problems some temporary skin damage have used a lotion Anhydrous Lanolin Lotion, could try that.

Basically I would speak to the physican that help you with the pitutary problem, excessive sweating is alot easier to treat then lack of sweat.

Good Luck, I know it sucks.....

oh, by the way I have read that lack of sweating can be caused in people who are poisoned, LoL cause Accutane is poison and most of us have been poisoned.....

Edited by oli girl, 02 October 2009 - 08:19 AM.

[jordan1234]

I have responded to the GH positively which is why I feel like my lack of sweat and nerve problems may be temporary. However, I often feel that it is just a problem that is localized to my face and nothing else, sometimes if I get really bad my shoulders and chest will flush, but since on the GH that has not happened. Is there anything topical that has help heal the skin? When my face is wet it is okay, it feels like the issue is a lack of hydration.

[Alex831]

Hi!

I have a huge problem:

Always after taking a accutane pills i got very severe flushing. After 3-4 month in my accutane treatment the flushing was sooo bad that i had to stop taking it. This was over 1 and a half year ago.

Now i have permanent redness on my cheeks and i have servere flushes at least twice a day. When i wake up in the morning i immediately feel some burning on my cheeks. Heat is also a trigger. But sometimes when i am just sitting in front my computer my face starts to flush. It also feels very hot when i touch it.

When i have a strong flush i also feel pressure behing my right eye.

All the flushing and redness in my face is driving me crazy.

Is this permanent? What can i do?
I never had any redness in my face before taking accutane. ((


Alex

[jordan1234]

Yo JT if you still on the blog right now hit me back

And Alex I feel like depending on the level of damage you have personally acquired over your accutane treatment the flushing may be permanent

[Seattle JT]

Hi!

I have a huge problem:

Always after taking a accutane pills i got very severe flushing. After 3-4 month in my accutane treatment the flushing was sooo bad that i had to stop taking it. This was over 1 and a half year ago.

Now i have permanent redness on my cheeks and i have servere flushes at least twice a day. When i wake up in the morning i immediately feel some burning on my cheeks. Heat is also a trigger. But sometimes when i am just sitting in front my computer my face starts to flush. It also feels very hot when i touch it.

When i have a strong flush i also feel pressure behing my right eye.

All the flushing and redness in my face is driving me crazy.

Is this permanent? What can i do?
I never had any redness in my face before taking accutane. ((


Alex

I would recommend reading through this entire thread. I know there is like 34 pages now, but it will give you the most thorough understanding of what we all have tried and understand about post accutane flushing...

Yo JT if you still on the blog right now hit me back

And Alex I feel like depending on the level of damage you have personally acquired over your accutane treatment the flushing may be permanent

Sorry man I just looked for a second. What's up?

[soul78]

Lamar im thinking about going on doxycycline for 4 or so months

thoughts would be great

although my flushing has decreased

my overall skin is not doing good..redness..mild acne,roughness

I was wondering whats ur thoughts on this and if its a good idea or not

and what dose would be the best 50 mg 75 mg 100 mg

and as far as i know doxy cant make flushing worse like accutane as they are not the same family

Hey halfpipe, are you still taking mepacrine? I think you said you were reducing yoru dose a while back - did it help the skin yellowing at all?

For what its worth, I took several courses of antibiotics after Accutane (including doxy) and it did not effect my flushing at all, did not make it worse in any way.

[soul78]

Lamarr, Halfpipe,

I started Meapcine afew weeks back and it definitely helps flushing and redness, it started helping from around the 3rd or 4th day. I am also taking Remeron, low dose Propranolol and low dose Clonidine.

My skin is starting to show some real signs of yellowing. I don't like it. Not sure what to do at this point. Any hints or ideas on how I can combat or lessen this yellowing? Any supplements? Dosing suggestions? I am taking 100mg per day at the moment.

I would be very greatful to hear if either of you know of any ways to help lessen the yellowing effect. Do you think I should just go yellow for a month or two and then reduce the dose? Do either of you know if the flushing remains less or stopped even after stopping Mepacrine? I don't mind going yellow for a couple months if I know it will solve the flushing even when I stop.

It's never easy...there is always something..it can be very frusterating to say the least.

Thanks

Edited by soul78, 07 October 2009 - 06:21 PM.

[Seattle JT]

Lamarr, Halfpipe,

I started Meapcine afew weeks back and it definitely helps flushing and redness, it started helping from around the 3rd or 4th day. I am also taking Remeron, low dose Propranolol and low dose Clonidine.

My skin is starting to show some real signs of yellowing. I don't like it. Not sure what to do at this point. Any hints or ideas on how I can combat or lessen this yellowing? Any supplements? Dosing suggestions? I am taking 100mg per day at the moment.

I would be very greatful to hear if either of you know of any ways to help lessen the yellowing effect. Do you think I should just go yellow for a month or two and then reduce the dose? Do either of you know if the flushing remains less or stopped even after stopping Mepacrine? I don't mind going yellow for a couple months if I know it will solve the flushing even when I stop.

It's never easy...there is always something..it can be very frusterating to say the least.

Thanks

I know that your questions weren't directed towards me, but I figure that I can give you some information while you wait for them to respond. You could try to lower your dose to 50mg per day to see if that decreases the yellowing. I also know that Lamarr was taking milk thistle which potentially could be decreasing the yellowing effect so that is something else to consider. If you find that these things don't decrease the yellowing to an acceptable level then you could also try switching to another anti malarial such as plaquenil. If you do a lot of research on it you will find that the risk of eye toxicity is very minor when used properly and with regular check-ups it can be caught early enough to prevent permanent damage.

From what I understand about the anti malarials and our condition I don't believe that it cures the flushing if you stopped taking it completely. It is presumably, at the least, a long term solution.

Hope that helps...

[soul78]

Lamarr, Halfpipe,

I started Meapcine afew weeks back and it definitely helps flushing and redness, it started helping from around the 3rd or 4th day. I am also taking Remeron, low dose Propranolol and low dose Clonidine.

My skin is starting to show some real signs of yellowing. I don't like it. Not sure what to do at this point. Any hints or ideas on how I can combat or lessen this yellowing? Any supplements? Dosing suggestions? I am taking 100mg per day at the moment.

I would be very greatful to hear if either of you know of any ways to help lessen the yellowing effect. Do you think I should just go yellow for a month or two and then reduce the dose? Do either of you know if the flushing remains less or stopped even after stopping Mepacrine? I don't mind going yellow for a couple months if I know it will solve the flushing even when I stop.

It's never easy...there is always something..it can be very frusterating to say the least.

Thanks

I know that your questions weren't directed towards me, but I figure that I can give you some information while you wait for them to respond. You could try to lower your dose to 50mg per day to see if that decreases the yellowing. I also know that Lamarr was taking milk thistle which potentially could be decreasing the yellowing effect so that is something else to consider. If you find that these things don't decrease the yellowing to an acceptable level then you could also try switching to another anti malarial such as plaquenil. If you do a lot of research on it you will find that the risk of eye toxicity is very minor when used properly and with regular check-ups it can be caught early enough to prevent permanent damage.

From what I understand about the anti malarials and our condition I don't believe that it cures the flushing if you stopped taking it completely. It is presumably, at the least, a long term solution.

Hope that helps...

Cheers JT, thanks for the info and suggestions. The stuff is pretty amazing, it really seems to shut things down, if you are considering I would opt to try it - that is 3 for 3 for it helping Accutane induced flushing.

Lamarr, Halfpipe, would still like to hear you thoughts...

[lamarr1986]

Heres what you wanna do...

Stay on the 100mg for as long as you can (atleast a few months). To combat the yellowing, go and get yourself some decent sunless tanner (xan tan is great). Use sunbeds for a while if you want, i know people say how damaging these are but sunbeds, so long as you cover your face, neck and back of your hands. Will only help things (it regulates the immune system and inflammation (google UVA-1 treatment in lupus))

Just use the sunless tanner on your face so you don't end up with a tanned body and white face. After a few months, lower your dose to 75mg daily then after a month lower it again to 50mg daily. While your flushing is much improved, start red light therapy and try and get yourself some curcumin.

I am only taking 200mg per week atm and my flushing is still 100% gone, but as i said i still use light therapy and curcumin (twice per day).

The mepacrin will leave your flushing much improved, especially if you stay on some of the anti flushing meds. It kind of knocks everything down a few pegs. Even if you were to come off after a month you will of still seen some permanent improvement.

Hope this helps,

Cheers.

[soul78]

Heres what you wanna do...

Stay on the 100mg for as long as you can (atleast a few months). To combat the yellowing, go and get yourself some decent sunless tanner (xan tan is great). Use sunbeds for a while if you want, i know people say how damaging these are but sunbeds, so long as you cover your face, neck and back of your hands. Will only help things (it regulates the immune system and inflammation (google UVA-1 treatment in lupus))

Just use the sunless tanner on your face so you don't end up with a tanned body and white face. After a few months, lower your dose to 75mg daily then after a month lower it again to 50mg daily. While your flushing is much improved, start red light therapy and try and get yourself some curcumin.

I am only taking 200mg per week atm and my flushing is still 100% gone, but as i said i still use light therapy and curcumin (twice per day).

The mepacrin will leave your flushing much improved, especially if you stay on some of the anti flushing meds. It kind of knocks everything down a few pegs. Even if you were to come off after a month you will of still seen some permanent improvement.

Hope this helps,

Cheers.

Hey Lamarr, encouraging info thanks! This is great to hear that even if I were to take it at 100mg per day for a month or two that the flushing would still be improved once coming off of it. I read a similar comment from someone over at the rosacea site, they were on it for a month and had to come off but still ended up with reduced flushing.

Good to hear that you are just taking 200mg per week as well! And still no flushing, great!

I am actually laready currently taking curcumin daily and also take Quercetin&Bromelain (helps with swelling).

Regarding xan tan, how do you find this? I have never used these tanning creams because I heard that make you look orange and are very noticeable. I used to use tanning beds back in the day when I worked out a lot but that went out the window when the flushing came along, probably a good thing. I could get away with just the face as it is winter here now and will be in sweaters and long sleeved shirts until April.

I would be curious to hear your experience with xan tan and if it made you look at all orangey? Did you use it while on Mepacrine?

Thanks again.

Edited by soul78, 11 October 2009 - 06:52 PM.

[Seattle JT]

Lamarr, Halfpipe,

I started Meapcine afew weeks back and it definitely helps flushing and redness, it started helping from around the 3rd or 4th day. I am also taking Remeron, low dose Propranolol and low dose Clonidine.

My skin is starting to show some real signs of yellowing. I don't like it. Not sure what to do at this point. Any hints or ideas on how I can combat or lessen this yellowing? Any supplements? Dosing suggestions? I am taking 100mg per day at the moment.

I would be very greatful to hear if either of you know of any ways to help lessen the yellowing effect. Do you think I should just go yellow for a month or two and then reduce the dose? Do either of you know if the flushing remains less or stopped even after stopping Mepacrine? I don't mind going yellow for a couple months if I know it will solve the flushing even when I stop.

It's never easy...there is always something..it can be very frusterating to say the least.

Thanks

I know that your questions weren't directed towards me, but I figure that I can give you some information while you wait for them to respond. You could try to lower your dose to 50mg per day to see if that decreases the yellowing. I also know that Lamarr was taking milk thistle which potentially could be decreasing the yellowing effect so that is something else to consider. If you find that these things don't decrease the yellowing to an acceptable level then you could also try switching to another anti malarial such as plaquenil. If you do a lot of research on it you will find that the risk of eye toxicity is very minor when used properly and with regular check-ups it can be caught early enough to prevent permanent damage.

From what I understand about the anti malarials and our condition I don't believe that it cures the flushing if you stopped taking it completely. It is presumably, at the least, a long term solution.

Hope that helps...

Cheers JT, thanks for the info and suggestions. The stuff is pretty amazing, it really seems to shut things down, if you are considering I would opt to try it - that is 3 for 3 for it helping Accutane induced flushing.

Lamarr, Halfpipe, would still like to hear you thoughts...

No problem man. I got Dr. Chu's information (from Lamarr) for my doctor and she was planning on contacting him about the use of antis. I have an appointment on November 4th so hopefully I can get an anti then. Honestly though i'm more worried about my muscle/joint issues than the flushing, but even if it just worked for my flushing I would be psyched as my flushing is still bad.

When I brought up anti malarials last time I definitely shocked her haha. She wasn't that excited about mepacrine as she said that it is used only for malaria in the States and wasn't supposed to be used for off-brand uses, but she may give me one of the other antis hopefully.

Edited by Seattle JT, 11 October 2009 - 08:19 PM.

[jordan1234]

Yo lamarr, what's up with the hair loss, is there anyway for me to stop it?

Edited by jordan1234, 12 October 2009 - 10:02 AM.

[oli girl]

Seattle- Have you been taking the Vit D? If so how long? Have you noticed any improvement in the joint clicking? I think that is one thing Vit D has helped with the clicking of the bones and joints.

[lamarr1986]

Yo lamarr, what's up with the hair loss, is there anyway for me to stop it?

Sorry bro i mean't to reply i get loads of messages on here!!

Well i use three things for my hairloss.... Topical steroids to suppress the inflammation/immune system. Essential oils ( i make my own mix of emu oil, jojoba oil, lavender and grapeseed) and a self built laser system (check out this website http://www.overmachogrande.com/).

I only use a very small amount of the steroids now as i want to keep things to a minimum.

I am indeed on only 200mg per week of mepacrin atm, BUT some of my side effects have creeped back at this dose. Dry knuckles/lips and my rayhnodes being the main things. My flushing still seems supressed....

Will see how bad these side effects come back and may up the dose of mepa slightly again.

Cheers

Xan tan gives a very natural appearance.... I started using it around the same time as starting the mepa as i wanted to prevent anyone from noticing the yellowing if i was to suffer from it... Remember the old articles saying a suntan covers up the yellowing? well that was my reasoning...

Seattle- Have you been taking the Vit D? If so how long? Have you noticed any improvement in the joint clicking? I think that is one thing Vit D has helped with the clicking of the bones and joints.

This is why i recommend sunbeds to post tane victims... we gotta keep those vitamin D levels up and in alot of us we can't absorb it properly from supplements now. Synthesis from UVB rays is one of the best ways of raising vitamin D3 levels.... i have been away from home for a while and i'm just about to go hit the sunbed now. Don't let the doctors scare you away from these, using it once a week (one week on the front of your body, next week on the back). Means that your skin isn't going to recieve much damage atall, plus i cover my hands/neck and face.

[ihateacnex12425]

hey i hope your still around here to help...


So i dont know if i am flushing or if it just the usual redness from the accutane that seems to be a more common thing.


How could you tell the difference?--------- Areas on face? How long?


My face right now has a red/pink tint to it. When I shower/ wash face(touch it) it will get redder for a little bit and then go back to a lighter pink.

I had tried to test it.. starting in mirror to see if that alone changes it (NO), hot spice food (NO).


Just seems to be when Im in hot areas (shower) and washing face does it get bad then goes back to the otherwise a tolerable pink/red color.