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Low-fat, high-fiber diet lowers androgens by 12% -- study says


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#1 Dotty1

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Posted 28 February 2008 - 10:47 PM

There is a study that concludes that low-fat, high-fiber diets lower androgens by 12%.


The summary of the study:
Low-Fat High-Fiber Diet Decreased Serum and Urine Androgens in Men

"To validate our hypothesis that reduction in dietary fat may result in changes in androgen metabolism, 39 middle-aged, white, healthy men (50–60 yr of age) were studied while they were consuming their usual high-fat, low-fiber diet and after 8 wk modulation to an isocaloric low-fat, high-fiber diet. Mean body weight decreased by 1 kg, whereas total caloric intake, energy expenditure, and activity index were not changed. After diet modulation, mean serum testosterone (T) concentration fell (P < 0.0001), accompanied by small but significant decreases in serum free T (P = 0.0045), 5-dihydrotestosterone (P = 0.0053), and adrenal androgens (androstendione, P = 0.0135; dehydroepiandrosterone sulfate, P = 0.0011). Serum estradiol and SHBG showed smaller decreases. Parallel decreases in urinary excretion of some testicular and adrenal androgens were demonstrated. Metabolic clearance rates of T were not changed, and production rates for T showed a downward trend while on low-fat diet modulation. We conclude that reduction in dietary fat intake (and increase in fiber) results in 12% consistent lowering of circulating androgen levels without changing the clearance. "


#2 LiliVG

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Posted 28 February 2008 - 11:32 PM

This study was not done well because there's no way to isolate which of the two factors they changed was responsible for the hormonal changes. Was it the fat, or the fiber?




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