2971 replies to this topic

[Scars4Life]

Where?

http://acell.com/pandr_surgery.html

Click on the data sheets on the left

I've been trying for the last hour or two to see them... Anyone else having difficulty?

Not really, I was able to click on them just fine. But as for the pictures, it looks like it can somewhat work for the hair, as for scars, it looks like a better version of a skin graft. I still didn't see any indented scars being treated, except for that infamous finger, but who knows the story behind that.

What if your entire face is just full of scars and whatnot, do you excise your entire face and apply pixie dust all over it, doesn't seem very practical. It seems like applying lugol's full face for a year in this case would probably do better, well if it works. Anyone tried it yet? Did you see the scar getting hyperemic?

[lac]

The finger can be at least half explained by the fact that fingertips normally are more regenerate-able than most things on the body. Happens more with children.


Acell did more for that finger than I would ever believe could be achieved by a band-aid and some disinfectant. Especially for a man that age. But I also doubt that magnitude of result could be repeated in most other areas of the body.

[Maldition]

decorin <<<< and apligraf <<<<<<... that 2 things are the answers... search!!!

what's news about juvista? i think that is another joke like 'acell' two lies..

[pepo]

im extremely interested in lugols solution aswell as im hoping it will help my stretch marks.

id appreciate it if you could send me the paper you were talking about NEOmike. ive been doing alot of research into it for the past month and actually saw a post you made on another site (curezone i think, small world eh). ive read both of doctor derrys papers and they are extremely interesting. ive tried to do more research but there doesnt seem to be alot of information out there at all. i think its just one of those treatments where im going to have to try it for myself to get any answers.

tbh it all seems a little too good to be true, but i have just ordered some lugols solution off hyperdrug. i have no idea if its any good but its cheap and pretty much the only place i can find that sells it. i figured if the worst comes to the worst then ive only wasted £4.

so im going to give it ago, but i would be extremely interested to hear from anyone else who has tried it or who is currently trying it. even if you've only been doing it a few days i would be interested to hear how it is going, as it is said that regeneration starts after only a couple of days.

i dont really know what to do so im just going to pore some lugols onto a cotton wool ball and then wipe it all over my stretch marks. ill do this for a couple of weeks and see if i see any changes. i know this is a short period of time but the doctor does state that the regeneration process only takes a couple of days to start, so i must be able to see whether its doing anything.

any help or thoughts would be appreciated

thanks

Edited by pepo, 15 November 2009 - 08:18 PM.

[Scars4Life]

Sounds about right. Well I am not really sure what to do either, seems like you just pour that stuff on your scar, make sure it stays in place and let it do its magic.

I guess I am going to go out and get it as well, and see what it will do on some of the scars I have on my arms before trying face. Unlike some people I will post about any changes/improvements/worsening, be prepared for the worst I am a harsh critic.

Btw exactly what lugol's did Dr. Derry used, there seems to be so many with all different intensities.

[lac]

Unless this doc is selling Lugol's solution I really don't see how this could be bullshit.

It's not gonna make him a medical superstar just to discover this. It's not gonna make him rich by offering specialized treatments of something at his own clinic either; the whole thing is too easy.

I don't see any motivation to exaggerate or lie, and I don't see much gray area for the success or failure of this. He's just saying chronically applied topical Lugol's heals scarring - either it works or it doesn't.




I am going to try it on a scar on my arm. It's an old childhood injury that has been there for at least 15 years now. It wasn't very deep or stitched up or anything, it's just a skin abrasion that bled & formed scar tissue on the surface in a spot about the size of a nickel or quarter.

[Maldition]

we speak in which scientifically it can make each substance:

Lugol or solution of Lugol is a diatomic iodine solution|I2 (1%) in balance with potassium iodide|KI (2%) in distilled water. It was appointed in honor the French doctor Jean Guillaume Auguste Lugol|J.G.A. Lugol

I ask. the potassium iodine or iodide as it can generate regeneration? it seems to me of science fiction, it is as to put an apple above of a scar and to say that it regenerates the skin.

God wants that this mistaking!

no more words guys, start treatment and then let see.


asked again : any news about juvista?

put eyes on 'decorine' <<< inhibition collagen, and cells can grow


pd: sorry my bad english .


'acell is a joke, i know , i hope all people knows '...

[NeoMike]

hi all together,

i think everything about topical iodine should be discussed in the new thread. some of you are already doing this.

@eterna:

why do you think acell is a joke?
it works, it may not work in the way we like it. but i still hope that there is a opportunity.
maybe future scaffolds will bring what we are all hoping.

these are interesting times and i think it's the best way to follow every path which brings us closer to the regeneration of scars. so why should we not use acell, iodine, stem cells etc. for our purpose? science will bring every year, every month news concerning our problem and i stíll believe that there is no miracle needed for scar regeneration. it will be the first thing which can be corrected if the regenerative medicine takes off.

stay tuned. everything will go it's way.

NEO

[Scars4Life]

Inspiring words there Neo.

[seabs135]

we speak in which scientifically it can make each substance:

Lugol or solution of Lugol is a diatomic iodine solution|I2 (1%) in balance with potassium iodide|KI (2%) in distilled water. It was appointed in honor the French doctor Jean Guillaume Auguste Lugol|J.G.A. Lugol

I ask. the potassium iodine or iodide as it can generate regeneration? it seems to me of science fiction, it is as to put an apple above of a scar and to say that it regenerates the skin.

God wants that this mistaking!

no more words guys, start treatment and then let see.


asked again : any news about juvista?

put eyes on 'decorine' <<< inhibition collagen, and cells can grow


pd: sorry my bad english .


'acell is a joke, i know , i hope all people knows '...

If ECM is non denatured, and the fibrils stay slender you will get site specific tissue. By the fact the intercellular cells can grow through the ECM. (When you are non wounded, the ECM in your body stay non denatured and you do not scar, your intercellular cells can pass through it)

So if it doesn't work then that means the ECM is denatured and has allowed crosslinking...

Trying to remain objective: The two Acell photos for me

1. No scar: The keloid one, you can not see any scarring. There could be some there, the picture may not have picked it up. However going on the picture: this shows the fibrils stayed non-crosslinked as you have site specific tissue with no scarring.

2. Scarring: The other picture of the MOHS, you can see scarring in the top half of the picture (bottom half seemed OK), therefor the ECM used was either denatured or become denatured which crosslinked the fibrils with excess collagen (i.e. you have scarring).

If the second one is the regular pattern I will not be using that type of ECM. If the keliod one was the regular result I'd use the ECM.

Edited by seabs135, 19 November 2009 - 01:27 AM.

[Maldition]

we speak in which scientifically it can make each substance:

Lugol or solution of Lugol is a diatomic iodine solution|I2 (1%) in balance with potassium iodide|KI (2%) in distilled water. It was appointed in honor the French doctor Jean Guillaume Auguste Lugol|J.G.A. Lugol

I ask. the potassium iodine or iodide as it can generate regeneration? it seems to me of science fiction, it is as to put an apple above of a scar and to say that it regenerates the skin.

God wants that this mistaking!

no more words guys, start treatment and then let see.


asked again : any news about juvista?

put eyes on 'decorine' <<< inhibition collagen, and cells can grow


pd: sorry my bad english .


'acell is a joke, i know , i hope all people knows '...

If ECM is non denatured, and the fibrils stay slender you will get site specific tissue. By the fact the intercellular cells can grow through the ECM. (When you are non wounded, the ECM in your body stay non denatured and you do not scar, your intercellular cells can pass through it)

So if it doesn't work then that means the ECM is denatured and has allowed crosslinking...

Trying to remain objective: The two Acell photos for me

1. No scar: The keloid one, you can not see any scarring. There could be some there, the picture may not have picked it up. However going on the picture: this shows the fibrils stayed non-crosslinked as you have site specific tissue with no scarring.

2. Scarring: The other picture of the MOHS, you can see scarring in the top half of the picture (bottom half seemed OK), therefor the ECM used was either denatured or become denatured which crosslinked the fibrils with excess collagen (i.e. you have scarring).

If the second one is the regular pattern I will not be using that type of ECM. If the keliod one was the regular result I'd use the ECM.

so, acell is ECM non denatured or not? perhaps if I above put decorin of acell to have better result...

maybe apligraf ECM non denatured ...I have approval regeneration in a photo here.

Edited by eterna_maldicion, 19 November 2009 - 03:43 AM.

[seabs135]

we speak in which scientifically it can make each substance:

Lugol or solution of Lugol is a diatomic iodine solution|I2 (1%) in balance with potassium iodide|KI (2%) in distilled water. It was appointed in honor the French doctor Jean Guillaume Auguste Lugol|J.G.A. Lugol

I ask. the potassium iodine or iodide as it can generate regeneration? it seems to me of science fiction, it is as to put an apple above of a scar and to say that it regenerates the skin.

God wants that this mistaking!

no more words guys, start treatment and then let see.


asked again : any news about juvista?

put eyes on 'decorine' <<< inhibition collagen, and cells can grow


pd: sorry my bad english .


'acell is a joke, i know , i hope all people knows '...

If ECM is non denatured, and the fibrils stay slender you will get site specific tissue. By the fact the intercellular cells can grow through the ECM. (When you are non wounded, the ECM in your body stay non denatured and you do not scar, your intercellular cells can pass through it)

So if it doesn't work then that means the ECM is denatured and has allowed crosslinking...

Trying to remain objective: The two Acell photos for me

1. No scar: The keloid one, you can not see any scarring. There could be some there, the picture may not have picked it up. However going on the picture: this shows the fibrils stayed non-crosslinked as you have site specific tissue with no scarring.

2. Scarring: The other picture of the MOHS, you can see scarring in the top half of the picture (bottom half seemed OK), therefor the ECM used was either denatured or become denatured which crosslinked the fibrils with excess collagen (i.e. you have scarring).

If the second one is the regular pattern I will not be using that type of ECM. If the keliod one was the regular result I'd use the ECM.

so, acell is ECM non denatured or not? perhaps if I above put decorin of acell to have better result...

maybe apligraf ECM non denatured ...I have approval regeneration in a photo here.

From my personal understanding, Decorin would keep the fibrils slender, stop excess collagen build up (scar) which would enable the intercellular cells to grow through the ECM.

I've seen the apligraf photo and you can see scar free healing.

Edited by seabs135, 19 November 2009 - 08:40 PM.

[katiekat]

we speak in which scientifically it can make each substance:

Lugol or solution of Lugol is a diatomic iodine solution|I2 (1%) in balance with potassium iodide|KI (2%) in distilled water. It was appointed in honor the French doctor Jean Guillaume Auguste Lugol|J.G.A. Lugol

I ask. the potassium iodine or iodide as it can generate regeneration? it seems to me of science fiction, it is as to put an apple above of a scar and to say that it regenerates the skin.

God wants that this mistaking!

no more words guys, start treatment and then let see.


asked again : any news about juvista?

put eyes on 'decorine' <<< inhibition collagen, and cells can grow


pd: sorry my bad english .


'acell is a joke, i know , i hope all people knows '...

If ECM is non denatured, and the fibrils stay slender you will get site specific tissue. By the fact the intercellular cells can grow through the ECM. (When you are non wounded, the ECM in your body stay non denatured and you do not scar, your intercellular cells can pass through it)

So if it doesn't work then that means the ECM is denatured and has allowed crosslinking...

Trying to remain objective: The two Acell photos for me

1. No scar: The keloid one, you can not see any scarring. There could be some there, the picture may not have picked it up. However going on the picture: this shows the fibrils stayed non-crosslinked as you have site specific tissue with no scarring.

2. Scarring: The other picture of the MOHS, you can see scarring in the top half of the picture (bottom half seemed OK), therefor the ECM used was either denatured or become denatured which crosslinked the fibrils with excess collagen (i.e. you have scarring).

If the second one is the regular pattern I will not be using that type of ECM. If the keliod one was the regular result I'd use the ECM.

so, acell is ECM non denatured or not? perhaps if I above put decorin of acell to have better result...

maybe apligraf ECM non denatured ...I have approval regeneration in a photo here.

From my personal understanding, Decorin would keep the fibrils slender, stop excess collagen build up (scar) which would enable the intercellular cells to grow through the ECM.

I've seen the apligraf photo and you can see scar free healing.

Seabs, can we get this, or is this something a doc has to do? How is it actually used?

[seabs135]

we speak in which scientifically it can make each substance:

Lugol or solution of Lugol is a diatomic iodine solution|I2 (1%) in balance with potassium iodide|KI (2%) in distilled water. It was appointed in honor the French doctor Jean Guillaume Auguste Lugol|J.G.A. Lugol

I ask. the potassium iodine or iodide as it can generate regeneration? it seems to me of science fiction, it is as to put an apple above of a scar and to say that it regenerates the skin.

God wants that this mistaking!

no more words guys, start treatment and then let see.


asked again : any news about juvista?

put eyes on 'decorine' <<< inhibition collagen, and cells can grow


pd: sorry my bad english .


'acell is a joke, i know , i hope all people knows '...

If ECM is non denatured, and the fibrils stay slender you will get site specific tissue. By the fact the intercellular cells can grow through the ECM. (When you are non wounded, the ECM in your body stay non denatured and you do not scar, your intercellular cells can pass through it)

So if it doesn't work then that means the ECM is denatured and has allowed crosslinking...

Trying to remain objective: The two Acell photos for me

1. No scar: The keloid one, you can not see any scarring. There could be some there, the picture may not have picked it up. However going on the picture: this shows the fibrils stayed non-crosslinked as you have site specific tissue with no scarring.

2. Scarring: The other picture of the MOHS, you can see scarring in the top half of the picture (bottom half seemed OK), therefor the ECM used was either denatured or become denatured which crosslinked the fibrils with excess collagen (i.e. you have scarring).

If the second one is the regular pattern I will not be using that type of ECM. If the keliod one was the regular result I'd use the ECM.

so, acell is ECM non denatured or not? perhaps if I above put decorin of acell to have better result...

maybe apligraf ECM non denatured ...I have approval regeneration in a photo here.

From my personal understanding, Decorin would keep the fibrils slender, stop excess collagen build up (scar) which would enable the intercellular cells to grow through the ECM.

I've seen the apligraf photo and you can see scar free healing.

Seabs, can we get this, or is this something a doc has to do? How is it actually used?

It is not for sale in any pharmacy were I live. Someone posted up a link on the decorin thread were it had a price.

What I've learned is decorin is a protein that is found in every unwounded tissue in your body, but it is more or less absent in wounds. It decorates the ECM and stops your non wounded tissues from becoming fibrous.

It has been shown to stop the fibrils from over expressing collagen (scar), so following logic if you apply it onto a wound that is in the process of laying new ECM, it would stop the fibrils from over expressing collagen.

BTW I'm no expert, I just follow what I have learned for myself like we all should.

Edited by seabs135, 19 November 2009 - 10:21 PM.

[NeoMike]

hi all,

i'v posted this link in another thread, but i think it's interesting here too.
It's about medical needling and it's relationship to regeneration.

LINK

maybe someone finds it elucidating.*g*

i don't know.

so long

NEO

[coconut scar]

Hello
I am also interested in the Lugols Iodine . i want to try on a small scar on my face but BRD warned us about long term iodine use and the potential dangers in another thread. however, i've heard more than a couple people, outside of the canadian doctor that say this stuff works from the bottom up.
if anyone has seen results with this ..i know this is fairly new here....please let everyone know..the regeneration of scars with iodine is worth investigating and yes perhaps we can start another thread with this topic.
one question the stain should not persist..how do we remove the stain..hopefully the stain will not become a permanent problem when other cleansers are used?
Thanks guys
Best of Luck to all !

[Tom_Mason]

Ok I've been reading all the posts recently.

I started this scarless healing thread back in 2007 and now we are approaching 2010.
So where does scarless healing stand.

The best option I see is still acell. I believe that doctor Jones needs to try another
patient as quite clearly it shouldn't have crusted over as it did and needed to be kept moist.

Acell now shows on its website http://www.acell.com/pandr_surgery.php

"ACell, Inc. has developed a proprietary line of plastic surgery and wound care devices utilizing an advanced regenerative medicine technology. ACell’s MatriStem technology is a naturally occurring bioscaffold derived from porcine tissue. When MatriStem is placed into a surgical site or wound, it is resorbed and replaced with new native tissue where scar tissue would normally be expected."

Is everyone just waiting for others to try it out? The product is there so what is causing the lack of take up?

Edited by Tom_Mason, 24 November 2009 - 10:57 PM.

[Maldition]

acell is a joke, is a publicity so that the actions of acell raise with lies (the same happens with juvista) the only thing that can give something of hope is the protein decorin, and I have seen a photo treatment scarless with apligraf but not sure...

I believe that juvista this giving the awaited results but is not a hope, by the way is necessary to hope until the 2011 to see the results of phase 3, and for when on sale officially this product?

[seabs135]

acell is a joke, is a publicity so that the actions of acell raise with lies (the same happens with juvista) the only thing that can give something of hope is the protein decorin, and I have seen a photo treatment scarless with apligraf but not sure...

I believe that juvista this giving the awaited results but is not a hope, by the way is necessary to hope until the 2011 to see the results of phase 3, and for when on sale officially this product?

We've seen one photo of could be complete scar free healing with acell and one with a bit scarring in it done over a biggish surface area.

It is still early days and is a mixed bag IMO

Anyway if you can have a non denatured ECM you will get scar free healing. The ECM on your unscarred tissue is the result of non-denatured ECM which has masses of the protein decorin keeping the fibrils non-crosslinked...

What we need is non denatured ECM.

The appligraf photo is a precedent to what we want.

Edited by seabs135, 25 November 2009 - 11:58 AM.

[Maldition]

acell is a joke, is a publicity so that the actions of acell raise with lies (the same happens with juvista) the only thing that can give something of hope is the protein decorin, and I have seen a photo treatment scarless with apligraf but not sure...

I believe that juvista this giving the awaited results but is not a hope, by the way is necessary to hope until the 2011 to see the results of phase 3, and for when on sale officially this product?

We've seen one photo of could be complete scar free healing with acell and one with a bit scarring in it done over a biggish surface area.

It is still early days and is a mixed bag IMO

Anyway if you can have a non denatured ECM you will get scar free healing. The ECM on your unscarred tissue is the result of non-denatured ECM which has masses of the protein decorin keeping the fibrils non-crosslinked...

What we need is non denatured ECM.

The appligraf photo is a precedent to what we want.

in my country an outstanding scientist that already is 72 years old and continues responding my email q has the same question ' when the tests with humanos' begin;
invention already for many years a colageno membrane, this difference of others in which he is ' direccionado' that is in theory direccion the colageno fibers unfortunately for want of bottoms the tests in humans not yet are realised not if this membrane that direction the colageno could to avoid that the colagen of the skin grows, and that allows the cells to grow, giving like result nonscar.
as always, to wait for and to wait for another option do not have

the page is in Spanish but the control translated to English:

http://www.translate.google.es/translate?h...julio%2F105.php

so that in fact we have 2 problems.
1: to avoid that it grows colageno fibers
2: the address...
this causes that the new skin grows equal q was before, without interlaced fibers of colageno like this in the normal skin. can't the skin not to grow normal.
it seems that the membrane that I put in the Link point 2. is no another product that direction the colageno like in the normal skin. as it is this membrane of the Dr. Grigera


pd: sorry my bad english (i know).

Edited by eterna_maldicion, 26 November 2009 - 07:25 AM.