Cystic acne runs in my family, and lucky me I have it too. I want accutane it's the only thing that has worked for other members of my family. But before I can take accutane I have to go through every other medication that I already know doesn't work (I've tried almost everything in the last 14 years.) I'm currently on spironolacton, minocyline, and ortho-tri-cyclen. The side effects of these are really starting to get to me. I'm so sleepy all the time I sometimes feel like I cant function. And I've been somewhat sick to my stomach for the last two days. I think it's the spironolacton it is actually a blood presure medication, and my blood presure is usually low to normal. Has anyone else had side effects like this? And advice?