Hi everyone I am very interested in this procedure and was wondering hat kind of scarring this would be best for.I noticed that there were some pics on the first page and people have had different opinions on whether they were minor of severe. I figured I would instead post pictures of scarring that is similar to mine. They are not what I believe to be severe but they bother me. They are for the most part indentations caused by larger pimples and a few very small pits almost look like enlarges pores. Would this procedure be beneficial?

Pictures of similar Scarring

Hi everyone I am very interested in this procedure and was wondering hat kind of scarring this would be best for.I noticed that there were some pics on the first page and people have had different opinions on whether they were minor of severe. I figured I would instead post pictures of scarring that is similar to mine. They are not what I believe to be severe but they bother me. They are for the most part indentations caused by larger pimples and a few very small pits almost look like enlarges pores. Would this procedure be beneficial?

Pictures of similar Scarring

hi everyone,
just to let you all know i had stem cell treatment from dr khan yesterday and I found him very caring and understanding as is his staff! After the initial fat was taken from my abdomen the cells were cultivated then injected into my open pores and scars, and most areas of my face he also performed subsicion on some of the scars then went over my whole face with a very fine needle I think he was injecting the fat deep into the dermis (maybe!). at this time my face and stomach are swollen and bruised and i have a few blood spots over my face. i have an appointment 7th dec to go back and get skin taken from my neck he is then going to seperate and cultivate the cells to hopefully give me my pigmentation back on my face, i gather he is going to either dermabrase or laser my face before he injects and sprays the cells onto my face to form new skin. I will keep you all posted on my progress. As I have previously stated I found dr khan and his staff the nicest people I have met on my journey to have normal skin

BRD,
I have been trying to talk to you many times. Please can you offer me any advice?
I was overfilled with fat graft taken from my innerknee to my lips at age 23.
All the fat seemed to take. My lip is too big,and bulky the fat nodules are peppered all
throughout the lip region including under my nose. I have had several attempts at cutting some of these nodules out..some were removed and some may have grown back??
Do you think the constant trauma of trying to cut them out is causing a reaction
where they could actually be regenerating? I just dont understand why my lip is getting worse
and worse. I am assuming I have alot of stem cells in my lip. Do you know any doctors or any procedures that can help me to reduce all these fat graft nodules? I have heard of
a doctor injecting 5fu to reduce the fibroblasts in the f/g but it seems to me that would be
temporary? Then another uses steroid injections,and yet another lipodissolve.
I am desperate for some help here.
I would also like to know is MRI the only test that would show where exactly the fat grafts are
or is there some easier test like ultrasound?
I feel like its just going to keep getteing bigger and bigger since the effect seems
"cumulitive" please respond to me, or pm me.
I have had these grafts for 16 years now.

BRD what about my post, did you see it?

dear all
all this science of stem cell fybroblasts has been around for some time, we have seen isolagen failure, now new product vavelta is available (embryonic stem cells), new products are to become available soon (Juvista for scarless healing after scar revision surgery). i am anyway still not at all convinced that all this would really work on large broad depressions. it will certainly improve skin quality and texture but i am remaining firm believer that scars have to be lifted by filler or implant to be kept lifted. I absolutely love the idea of dermal pocket grafting. your own deepithelised skin graft works as a implant, its autologous very long lasting, it will become if taken part of your own tissue. i am sure it will bring some of fresh fybroblasts in as well as theres some fat tissue left on the acctual graft. unfortunately this seems to be largely overlooked procedure in UK. its available by few docs in states and in Australia,here in UK doctors keep using short acting and altogether unsuitable fat transfer. i think one of reasons is you need dermabrader to take the epithel off before you harvest the graft. dermabrasion has disapeared from UK and Europe and therefore graft cannot be properly prepared. as for the most effective lifting agent i think silicone remains the best in terms of natural looks and longevity, but of course one has to live with synthetic substance in face. i cannot help but hope that some dermatologist here will finally wake up and start utilizing dermal pocket grafting.

What clinics across the world are currently offering this procedure ?

In particular which clinic performed the treatment shown in this photos from the post at the beginning of this thread ?

http://img232.imageshack.us/img232/1989/st...acnescarib9.jpg

thank you for warm welcome. i am very happy you have repaired some of my inaccurate descriptions. i was writing that post very fast and i wasnt paying enough attention to the "niceties"in text. i am very well aware of the diference btw adipocyte, fibroblast and stem cell, its anyway my believe that any stem cells we want to inject have to primarily turn into fibroblasts if any collagen production has to be achieved. back to basic as with regards to fat transfer: there are number of renewed dermatologists in united states who consider fat not suitable as such, after you inject it however careful you are fat stars to live its own life in your skin, it can die very fast, it can remain and it can turn bulky big and unsightly.this is very difficult to predict and therefore you never know how you going to end up. there were number of people on different posts with less then satisfactory experience. its my believe that it would have been better to use dermal graft as transporter of either progenitor fibroblasts of stem cells, graft would have filled defect and cells would have effectively improve quality of skin. as for silicone i fully understand your concerns towards safety of this, if you anyway have severe tissue and volume loss and it affects your life to the extend of social suicide, its a good and lasting procedure. there are number of very succesful stories of people who had this done years ago and didnt have any problem at all. at the end of the day is everybodys choice dependent on many factors. thank you in any case for this great post and for all your inteligent comments.
Hi askin77,

First and foremost, welcome to the forum.

I am under the impression that you did not read the entire thread, because you seem to be confusing a few terms that have already been discussed at length. For one, you incorrectly equate fibroblasts and stem cells. You then seem to imply that the methodology discussed here would be ineffectual by tying it to what you perceive as the failures of fibroblast based products, traditional adipose transplantation and standalone PRP. All in all this does suggest a lack of familiarity with this thread's central discussion. Therefore I kindly ask that you read it beginning to end in order to inform yourself about the nature of the topic and relevant details herein.

I will address some of your specific comments below.

askin77: "[...] stem cells fibroblasts have been around for some time [...]"

Response: Technically speaking, fibroblasts are not exactly stem cells. Fibroblasts synthesize connective tissue, glycoproteins, etc (useful for wound healing), but they are generally considered to be near terminally differentiated. Their ability to undergo morphological changes under normal circumstances is very limited. True stem cells on the other hand are much more potent and can rather easily differentiate into fibroblasts and other cell types. That's what makes them effective when they are properly utilized.

Stem cells can be ranked in terms of their potency. Omnipotent stem cells are by far the least differentiated, and therefore the most potent stem cells capable of creating an entire organism. Pluripotent are next in rank, followed by multipotent cell types found in adults. An example of the latter is adipose derived mesenchymal stem cells that are capable of differentiating into cell types found in and around subcutaneous fat. That's why they can be useful when dealing with atrophic acne scars, which are essentially visible on the skin surface due to missing tissue normally found at the dermal and hypodermal levels.

askin77: "I absolutely love the idea of dermal pocket grafting. your own deepithelised skin graft works as a implant, its autologous very long lasting, it will become if taken part of your own tissue."

Response: I also like the idea of dermal grafting. When done right it works, just like the methodology I currently employ. When transplanted, adipose derived mesenchymal stem cells can differentiate into various other cell types found at the site of injection/transfer/transplantation. They take their differentiation cues from the surrounding tissue and, in the case of how I use them, from a temporary autologous scaffold composed of blood and extracellular matrix particulates. This, done in combination with an instigated localized inflammation from subcision and needling, can make them rather effective in elevating/flattening skin depressions.

askin77: "[...] doctors keep using short acting and altogether unsuitable fat transfer."

Response: Fat grafting is short lasting only when done improperly. If it is handled incorrectly during the extraction, processing and transfer phases a large a majority of adipose and imbedded stem cells will die, making it next to impossible for most of the transplanted tissue to integrate itself into the transplantation site. Thus the body reabsorbs it over a few months time. On the other hand, when this procedure is done properly, the added tissue can last and even grow for decades to come. Just ask Jaden, who posted about her experience yesterday. (note: I presume Jaden is a female, pardon me if I my presumption is incorrect.) I should also mention that if one can increase the number of stem cells in the transplanted tissue, long term results should be even more apparent. Either way, I only use adipose tissue when I specifically contour the shape of the face and/or fill in large areas of atrophied tissue.

askin77: "as for the most effective lifting agent i think silicone remains the best in terms of natural looks and longevity [...]"

Response: Silicone is in my opinion quite dangerous when used as a lifting agent. One must always face the short, medium or long-term possibility of an immunological reaction to this foreign substance, however "inert" it may be. Localized and systemic effects can never be ruled out. Thus I have stayed away from it.

askin77: "little update on PRP on www.my-cells.net: it will last about 12 months then you need to have top up. for 6. 500 pounds."

Response: We are all at mercy of the natural aging process. Any benefit we get from a procedure will over time be counteracted by the unforgiving winds of time. Nonetheless, PRP in conjunction with subcision, needling and adipose derived mesenchymal stem cells can be an effective weapon in our battles with the realities borne out from our scars, injuries and mortality. The comprehensive procedure I discuss in this forum can benefit us long-term, potentially doing so well into our golden years.

I hope you do not see my reply to your posts as rude and therefore demeaning in any way, form or fashion. I simply want to clarify certain terms and procedures brought up in your original post so that the consequential discussion remain maximally objective.

Once again, welcome to this forum.

BRD

little update on PRP on www.my-cells.net: it will last about 12 months then you need to have top up. for 6. 500 pounds.
it brings me back to one and only thing dermal grafting. datura had one round i think, wonder how well it worked...

hi everyone,
just to let you all know i had stem cell treatment from dr khan yesterday and I found him very caring and understanding as is his staff! After the initial fat was taken from my abdomen the cells were cultivated then injected into my open pores and scars, and most areas of my face he also performed subsicion on some of the scars then went over my whole face with a very fine needle I think he was injecting the fat deep into the dermis (maybe!). at this time my face and stomach are swollen and bruised and i have a few blood spots over my face. i have an appointment 7th dec to go back and get skin taken from my neck he is then going to seperate and cultivate the cells to hopefully give me my pigmentation back on my face, i gather he is going to either dermabrase or laser my face before he injects and sprays the cells onto my face to form new skin. I will keep you all posted on my progress. As I have previously stated I found dr khan and his staff the nicest people I have met on my journey to have normal skin