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> Sore joints and muscles from accutane, What exactly causes this side effect?
MinxyMech
post Apr 11 2006, 05:26 AM
Post #1


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Joined: 27-February 06
From: South Africa



Hi there,

I suffer with lower back pain, been on accutane for almost 6 weeks now. I run about 30kms a week and have had to cut down on the amount of running I normally do because of mainly sore hip joints. I also have sore muscles in my legs, but it's not that bad. The sore hip joints however are seriously painful. I was wondering what the accutane actually does to give one this side effect.. maybe I could treat it. Anyone?

I take omega 3 twice a day and it doesnt' seem to be of much help. doubt.gif
------------
MinxyMech's Regimens

Pill Popping:
Accutane 50mg a day, started 6 March 06, for 4 months
Multivitamine once a day
Female support Supplement herbs; don quai, black cohosh, vitex and ginseng once a day
Omega 3 (Fish oil and Flaxseed oil) twice a day
Milk thistle once or twice a week

Skin:
Wash with Neutrogena extra mild cleansing cream twice a day
Moisturise once a day with Happyderm
Blistex on lips every hour - marvellous stuff
!


My Accutane Gallery

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DawgDaze64
post Apr 11 2006, 06:03 AM
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Joined: 3-April 06



QUOTE(MinxyMech @ Apr 11 2006, 05:26 AM) [snapback]1075354[/snapback]

Hi there,

I suffer with lower back pain, been on accutane for almost 6 weeks now. I run about 30kms a week and have had to cut down on the amount of running I normally do because of mainly sore hip joints. I also have sore muscles in my legs, but it's not that bad. The sore hip joints however are seriously painful. I was wondering what the accutane actually does to give one this side effect.. maybe I could treat it. Anyone?

I take omega 3 twice a day and it doesnt' seem to be of much help. doubt.gif


No one is quite sure. At the very least, it probably has to do with an overall drying effect on the body. Some research is being done that shows Accutane may also decrease hyaluronic acid and bone mineral density and may cause calification of tendons.

While Accutane side effects are considered short term, I know of many people, including myself, who believe the drug affected their joints for the long run. Get a thorough exam from a doc to see if there are other issues, though. And you may want to consider cutting back your running for the duration. It was recommended to me to stop all high impact aerobic activities while on the drug. Best of luck with your treatment.
------------


My regimen:

Mornings:
Neutrogena Fresh Foaming Cleanser
Paula's Choice Skin Balancing Toner, Oily/Combination Skin (no alcohol, tons of antioxidants)
Duac gel
Clinique's Super Defense Triple Action Moisturizer SPF 25 Normal to Oily Skin

Evenings:
Neutrogena Fresh Foaming Cleanser
Paula's Choice Skin Balancing Toner, Oily/Combination Skin (no alcohol, tons of antioxidants)
Retin A
Paula's Choice Skin Balancing Moisture Gel Normal to Oily/Combination Skin

Make-Up (on the days I have to wear it for business, etc.):
Either Almay's Clear Complexion Blemish Healing Makeup Oil Free
or
Estee Lauder Equalizer Smart Makeup for Combination Skin SPF 10
Both these foundations impart a smooth, silky, non-oily finish and neither dry out my face nor make it break out. I apply a very light coat with a damp makeup sponge and then set with MAC Studio Finish Face Powder. To conceal blemishes, I take a very fine makeup brush, dip it in foundation and then in powder, dot on blemish, and blend, blend, blend. This method provides even, natural looking coverage for almost any pimple.
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beentheredonetha...
post Apr 11 2006, 07:14 AM
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Joined: 25-November 02
From: Tampa, FL



The theory is that it dries out the connective tissues and cushioning fluids in the joints. It seems that taking fish oil supplements really helps - they have an anti-inflammatory effect and somehow aid in the lubrication of joints.
QUOTE
Some research is being done that shows Accutane may also decrease hyaluronic acid

Do you have a link to this research? My google searches find pages with the opposite finding.
------------
Currently - all clear!
Maintaining my last Accutane course (10/05-04/06) click here for log
Yasmin on Seasonale schedule
Green Cream lvl 6
Shiseido White Lucent system
(cleanser, and SPF 16 moisturizer (no way, SPF that doesn't sting!?))
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MinxyMech
post Apr 11 2006, 07:25 AM
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Joined: 27-February 06
From: South Africa



Thanks for your replies.
I'm really a fitness freak, am absolutely addicted and can't see how I'm going to cut my running out completely. But, if I have to I should.
------------
MinxyMech's Regimens

Pill Popping:
Accutane 50mg a day, started 6 March 06, for 4 months
Multivitamine once a day
Female support Supplement herbs; don quai, black cohosh, vitex and ginseng once a day
Omega 3 (Fish oil and Flaxseed oil) twice a day
Milk thistle once or twice a week

Skin:
Wash with Neutrogena extra mild cleansing cream twice a day
Moisturise once a day with Happyderm
Blistex on lips every hour - marvellous stuff
!


My Accutane Gallery

Go to the top of the page
 
+Quote Post
DawgDaze64
post Apr 11 2006, 07:34 AM
Post #5


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Group: Veteran Members
Joined: 3-April 06



QUOTE
Do you have a link to this research? My google searches find pages with the opposite finding.


Hi beentheredonethat:

Insert this into a Google search: Thalidomide II: The Horrors and Life-long Side Effects from the Acne Drug, Accutane, and a Potential Cure. The link to this PDF document should come up as the first result. Upload it and go to page four, right hand column, under the sub-heading "The HA Connection."
------------


My regimen:

Mornings:
Neutrogena Fresh Foaming Cleanser
Paula's Choice Skin Balancing Toner, Oily/Combination Skin (no alcohol, tons of antioxidants)
Duac gel
Clinique's Super Defense Triple Action Moisturizer SPF 25 Normal to Oily Skin

Evenings:
Neutrogena Fresh Foaming Cleanser
Paula's Choice Skin Balancing Toner, Oily/Combination Skin (no alcohol, tons of antioxidants)
Retin A
Paula's Choice Skin Balancing Moisture Gel Normal to Oily/Combination Skin

Make-Up (on the days I have to wear it for business, etc.):
Either Almay's Clear Complexion Blemish Healing Makeup Oil Free
or
Estee Lauder Equalizer Smart Makeup for Combination Skin SPF 10
Both these foundations impart a smooth, silky, non-oily finish and neither dry out my face nor make it break out. I apply a very light coat with a damp makeup sponge and then set with MAC Studio Finish Face Powder. To conceal blemishes, I take a very fine makeup brush, dip it in foundation and then in powder, dot on blemish, and blend, blend, blend. This method provides even, natural looking coverage for almost any pimple.
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beentheredonetha...
post Apr 11 2006, 08:20 AM
Post #6


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Joined: 25-November 02
From: Tampa, FL



Yeh, that's the propaganda piece that is full of misinformation. I mean a link to actual research.

The only research i've been able to locate indicates the exact opposite effect in pig skin - pigs are often used in medical reasearch because of their medical simularity to humans.

QUOTE
Epidermal hyaluronic acid synthesis in pig skin is increased by all-trans-retinoic acid, all-trans-retinyl acetate, 13-cis-retinoic acid (that's isotretinoin = Accutane) and etretinate.
------------
Currently - all clear!
Maintaining my last Accutane course (10/05-04/06) click here for log
Yasmin on Seasonale schedule
Green Cream lvl 6
Shiseido White Lucent system
(cleanser, and SPF 16 moisturizer (no way, SPF that doesn't sting!?))
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medic
post Apr 11 2006, 08:57 AM
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MinxyMech I noticed you take multivitamins. Make sure there is no Vitamin A in them.

DawgDaze64
I checked the article and here we go.

Page 2 - “This child was a happy, well-balanced,
forward-thinking child who had a great
deal to live for. This was psychotic and
the only conclusion we have been able
to draw is the Accutane poisoned him.�
--Julie Bishop, mother of Charles Bishop who
flew a plane into a building and committed
suicide.
Fifteen-year old Charles Bishop flew a suicidal
mission into an office building in Tampa, Florida.
Bishop had been taking Accutane.

He had never taken it! That's proven.
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beentheredonetha...
post Apr 11 2006, 09:06 AM
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Group: Veteran Members
Joined: 25-November 02
From: Tampa, FL



Yep, he had no trace of it in his system at the autopsy. The whole article is highly questionable.
------------
Currently - all clear!
Maintaining my last Accutane course (10/05-04/06) click here for log
Yasmin on Seasonale schedule
Green Cream lvl 6
Shiseido White Lucent system
(cleanser, and SPF 16 moisturizer (no way, SPF that doesn't sting!?))
Go to the top of the page
 
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medic
post Apr 11 2006, 09:13 AM
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Good advice on supplemental vitamins and minerals at least.
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DawgDaze64
post Apr 11 2006, 12:25 PM
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While I think a lot of medical info, pro and con, is propaganda of some sort smile.gif this piece does look suspect, now that I look at it further. I can't find it's references, for instance. Oddly, it was included in a packet of info given to me by my family doc, when I was discussing with her the pros and cons of my going on another round of Accutane.
------------


My regimen:

Mornings:
Neutrogena Fresh Foaming Cleanser
Paula's Choice Skin Balancing Toner, Oily/Combination Skin (no alcohol, tons of antioxidants)
Duac gel
Clinique's Super Defense Triple Action Moisturizer SPF 25 Normal to Oily Skin

Evenings:
Neutrogena Fresh Foaming Cleanser
Paula's Choice Skin Balancing Toner, Oily/Combination Skin (no alcohol, tons of antioxidants)
Retin A
Paula's Choice Skin Balancing Moisture Gel Normal to Oily/Combination Skin

Make-Up (on the days I have to wear it for business, etc.):
Either Almay's Clear Complexion Blemish Healing Makeup Oil Free
or
Estee Lauder Equalizer Smart Makeup for Combination Skin SPF 10
Both these foundations impart a smooth, silky, non-oily finish and neither dry out my face nor make it break out. I apply a very light coat with a damp makeup sponge and then set with MAC Studio Finish Face Powder. To conceal blemishes, I take a very fine makeup brush, dip it in foundation and then in powder, dot on blemish, and blend, blend, blend. This method provides even, natural looking coverage for almost any pimple.
Go to the top of the page
 
+Quote Post
FrankieBGirl
post Apr 11 2006, 05:56 PM
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Group: Veteran Members
Joined: 5-February 05



That Tampa plane crash pisses me off... I hate when it's brought up and it makes me feel like most of the hype associated with accutane is all scare tactics because this freaking nightmare of a 15-year-old wanker had never taken Accutane..he only had a prescription for it. He was a psycho on his own free will, and accutane had NOTHING to do with it.. But yet it was overly hyped that he had Accutane. Then after it was proven that he had never taken the drug, it was barely mentioned..leaving the impression in your mind that Accutane in fact makes you fly planes into bank buildings. Another doozy of a side effect. Maybe it was subliminal...You now don't even have to take the pill, just get the prescription written for it and you will turn into a crazy person!!!

And that article is another piece of garbage posing as scientific research floating around the internet.
*puts on my Donald Trump wig*
Al Gore is fired for creating the internet!!!! And whoever wrote that article is FIRED, and Julie Bishop, mother of 15 year old nightmare Charles Bishop is FIRED!!!!!!!!



Christ Almighty I need a Tylenol. lol
------------
~*~ Can you at least bring me my chapstick? But my lips hurt real bad!!!!~*~
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beentheredonetha...
post Apr 12 2006, 07:21 AM
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Joined: 25-November 02
From: Tampa, FL



QUOTE
You now don't even have to take the pill, just get the prescription written for it and you will turn into a crazy person!!!

Osmosis! crazy2.gif

QUOTE
*puts on my Donald Trump wig*
Al Gore is fired for creating the internet!!!! And whoever wrote that article is FIRED, and Julie Bishop, mother of 15 year old nightmare Charles Bishop is FIRED!!!!!!!!

rofl
------------
Currently - all clear!
Maintaining my last Accutane course (10/05-04/06) click here for log
Yasmin on Seasonale schedule
Green Cream lvl 6
Shiseido White Lucent system
(cleanser, and SPF 16 moisturizer (no way, SPF that doesn't sting!?))
Go to the top of the page
 
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FrankieBGirl
post Apr 12 2006, 01:38 PM
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Joined: 5-February 05



LOL Whoa I just re-read my post and apparently I was having a bad day? Whewwww and I haven't even started ACcutane yet... However, the mood swings are starting. I guess osmosis is true.
------------
~*~ Can you at least bring me my chapstick? But my lips hurt real bad!!!!~*~
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d_headshot
post Nov 30 2008, 04:31 PM
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QUOTE (beentheredonethat @ Apr 11 2006, 08:14 AM) *
The theory is that it dries out the connective tissues and cushioning fluids in the joints. It seems that taking fish oil supplements really helps - they have an anti-inflammatory effect and somehow aid in the lubrication of joints.
QUOTE
Some research is being done that shows Accutane may also decrease hyaluronic acid

Do you have a link to this research? My google searches find pages with the opposite finding.


I thought you couldn't take fish oil because of the high amount of vitamin a in the oil and the accutane?
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themintyness
post Dec 2 2008, 02:17 PM
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To use a simplified analogy, think of a car running without oil, or running low on oil. (oil as in oil change, not the gas for fuel). The car's gears, mechanical parts, etc. would be GRINDING against each other without the necessary lubrication. It's basically the same with Accutane. Obviously, it's done a lot of good, but the side effects are pretty bad.

By the way, I don't mean to offend anyone by my accutane statements. It sounded like a miracle when I first heard about it but I'm 21 and I have arthritis so it's never going to be an option for me.
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