History of Acne Medications

  • 1902 - X-Rays
  • ~1930 - Benzoyl Peroxide, topical
  • 1954 - Tetracycline, oral (oral antibiotic)
  • 1961 - Tretinoin, topical (Retin-A); Cyproterone acetate, oral
  • 1969 - Minocycline, oral (oral antibiotic)
  • 1972 - Clindamycin, topical (Cleocin-T)
  • 1976 - Tetracycline, topical (topical antibiotic)
  • 1979 - Isotretinoin, oral (Accutane)
  • 1982 - Isotretinoin, topical (topical Accutane)
  • 1983 - Azelaic acid, topical (Azelex)
  • 1996 - Adapalene (Differin)
  • 1997 - Sodium Sulfacetamide (Klaron)

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