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Accutane (isotretinoin)
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Brand: Accutane

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Accutane (isotretinoin)


Active Ingredients:
Isotretinoin in 10-mg, 20-mg and 40-mg soft gelatin capsules.

Inactive Ingredients:
Beeswax, butylated hydroxyanisole, edetate disodium, hydrogenated Soybean oil">soybean oil flakes, hydrogenated vegetable oil, and Soybean oil">soybean oil. Gelatin capsules contain glycerin and parabens (methyl and propyl), with the following dye systems: 10 mg - iron oxide (red) and titanium dioxide; 20 mg - FD&C Red No. 3, FD&C Blue No. 1, and titanium dioxide; 40 mg - FD&C Yellow No. 6, D&C Yellow No. 10, and titanium dioxide.

Items marked with red have tested a 3 or above (out of 5) in comedogenic (pore-clogging) testing.

The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.

Accutane (isotretinoin)

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Accutane (isotretinoin)

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Reviewed on June 8, 2016

Took it for 6months left with indented scarrings. I never get scars before accutane no matter how big my zit was wether i pop it or not, it never left a scar. But every pimple i got during my course left dents. I don't know if i'm gonna keep getting them but accutane is my biggest regret. I should've tried other options. If you're planning to go on accutane, pls don't risk it. You may or may not get the results you want. You can't be sure. I'm having a lot of gas and constipation as well.

by TinaSI on 07/15/2016 18:53
Have you been picking on your skin while on the drug? If you do ANYTHING to your face it will likely leave a scar.
Worked For Me!
Reviewed on June 2, 2016

There is a higher ratio of people leaving negative reviews on accutane than positive reviews because many people who reaped the benefits don't come back to write " it worked for me" , but here I am to say " IT WORKED".

My dermatologist had been encouraging me to take accutane for years now but I was scared from reading all the negative reviews ,so I resorted to natural methods ( which did not work to the magnitude I desired). After finally giving up, I gave it a shot and luckily for me I experienced the common side-effects which go away after discontinuing the drug.

I was 19 years old when I took the drug, female, 5'4, weighed around 120 ( for the people who care about stats). Did not take birth control because I didn't want any extra drugs circulating my system especially when accutane is a strong drug on its own. Avoiding pregnancy was not an issue for me so my doctor was lenient about this. I took Accutane - 30 mg for the first two month. Epuris- 40 mg for the other 4 months. I started in May 2015 and ended in November 2015.

The type of acne I had was related to unbalanced hormones, stress, poor diet- all factors which I had a hard time fixing due to being a full time university student. Stress and poor diet was unavoidable in my case no matter how hard I tried. Problematic areas for me were my cheeks and sometimes forehead, it was not flaming red acne all over my face. I was still able to cover it up with makeup but vanity was not my reason to take it. It was very painful, I would get cysts on my cheeks and back ( had been suffering from bacne for 6 years now).

During the first month, I felt the common side effects of dry lips, dry skin, aching back. The most problematic side effect for me was the back aches and the knees cracking so I asked my doctor to switch me to another brand Epuris which alleviated some of the back pain.

For the remainder of the treatment, the dryness was my pressing issue. No matter how much lip balm I used , they always felt chapped and dry. My skin was very dry so I constantly moisturized with Ponds. I also had a very dry scalp causing me to have dandruff but that quickly went away when I started using mustard oil before shampooing almost 3 times a week. The mustard oil REALLY HELPED keep the scalp dryness at bay. Most days I wouldnt have aches but few days I would experience bach aches. I was also very keen on applying sunscreen twice a day, your skin becomes very sensitive.

In terms of grooming, I stopped waxing my face, eyebrows, stopped laser and electrolysis treatments for a year total. Threading was the best way to go. If you opt for this, please let your person know so they can be slow and careful with your skin.

My acne started disappearing right away when I started taking away with a flare up during the 4 month. It wasn't a severe flare up , a few pimple on the lower right side of my cheek but at that point it felt like alot because I had gotten used to my new skin. The flare up cleared in a week and a half. Ever since I have been clear and only get a few small pimples here and there, those are usually related to poor skin care, like leaving my makeup on overnight.

After discontinuing the treatment, my dryness subsided in about 2 months. 2 months post-accutane my lips were back to normal. My skin and scalp were not too dry but wasn't oily either, I'd like to say normal. The back aches still occurred after stopping the treatments but completely stopped after about 6 months. I am clear and pain-free now.

For me it worked really well with side effects that were tolerable and went away after stopping the treatment. I would do it again if I had to ( hopefully I don't have to). If you are able to stick through the side effects, then it will be worth it. At the same time, I want everyone to understand your body chemistry will be different than mine so the severity and types of side effects may be different. I had a positive experience which is why I wanted to share mine with you accutane hopefuls out there. Good luck !

Don't risk it
Reviewed on May 2, 2016

I was on accutane 10mg for 3 weeks. (I'm female, 5'3 and around 126 pounds) Then got moved up to 20mg which I have been taking for a month. My dermatologist appointment is tomorrow,and I'm telling her I'm not taking this medication anymore.

I know this is a very low dose to be on, but my side effects show just how harsh this drug is. I have SEVERE abdominal pain 3-4 times a day with back pain and nausea. I'm so worried, I have no idea what it is but I've never ever had stomach problems before and it's a coincidence how this comes up when I get on accutane..

I have researched this side effect and it's supposedly rare,which doesn't make me feel any better. No amount of clear skin is worth the pain I'm in at the moment. It's a shame because my skin was starting to look like it was improving, but I can't spend every morning dreading the day ahead of me knowing I'll be in agonising pain.

I know what it's like to read the bad reviews on accutane and just think of the clear skin you'll have so you use the whole "it won't happen to me" but honestly, if I could go back a couple of months and someone told me this is what was going to happen, no way would I of taken it. I know accutane has helped so many people clear their skin but many of those same people get health issues years and years later.

This drug should be banned, I wish I never considered it.

Update: I told my dermatologist and she didn't seem shocked at all. She suggested moving me back down to 10mg but didn't seem concerned about the worrying side effects I'm having. I've stopped the medication and I'm going to my family doctor to hopefully get some tests done to put my mind at ease, or potentially find out what's gone wrong. Biggest regret of my life.

Last update: I've had 3 doctors and 2 surgeons examine my stomach. I've had blood tests, and even an ultrasound, but nothing is showing up. I've been off of accutane for almost a month and the pain is still awful. My dermatologist still insists it was not the drug that caused this, but doctors think otherwise. My digestive system has also been effected horribly by this drug, as well as the back pain and nausea continuing..

by danluna97 on 05/31/2016 01:17
I ended up with the same fate. Went to Doctors over and over again in till i got a endoscopy done. I would recommend getting one. Got on antacids back in 2011 and to this day I still have to take them sometimes. Still experience stomach pain sometimes. I know this dosent happened to everyone but I would just be careful you can potentially ruin your stomach. Worst decision I ever made in my life.
by M1997 on 06/26/2016 20:53
I hadn't seen anyone else on here experiencing the same side effect so I assumed I was a very rare case, it was honestly the most pain I've ever been in in my life,and that's on one of the lowest doses! My digestive system seems to have improved but I'm the same where I still get stomach pains and bad back pain every now and again, and I've been off of the drug for almost 2 months. It has helped so many people but in my opinion it's just not worth it, I've been eating dairy free since coming off of accutane and my skin has cleared up like 90% already, I'd recommend giving that a try to anyone before considering going on accutane!!
by dou on 06/27/2016 13:27
How's ur acne after a month?
by hatetane on 07/03/2016 10:28
Very common story. thanks for sharing.
by M1997 on 08/11/2016 10:26
Hi Dou, My acne has prettymuch gone now all I'm dealing with is scarring and the odd spot every now and then (I'm still in my teens). I really recommend everyone to try switching to "LUSH" skincare (or other natural products) and eliminating dairy from their diet for a few months to see if it makes a difference to their skin, the combination of the two has made my skin the best it's been in years. I think people under estimate how bad dairy is for us, the hormones and pus in milk is going to break us out because it's meant for baby cows not the human body!! Just remember to check the ingredients on EVERYTHING because milk can even be found in some brands of crisps ect. Good luck:)
Accutane has changed my life- for the better! <3
Reviewed on May 18, 2016

Well where can I start? I had acne since I was about 14 and it lasted me all through high school (fun). I am now 20. I was so embarrassed because it was getting so bad it got to the point where I started getting some cystic pimples!. Finally, I visited my dermatologist in 2014, who helped clear my acne with topicals but the acne returned, and she immediately suggested Accutane because she knew how long I struggled and how much the antibiotics and topicals weren't working. All I can say is that 6 months on Accutane was soo worth it because my skin was soooooo clear I got so many compliments and people were asking me what I been using!. I could eat what I wanted and not worry about getting terrible pimples. I did have to stop after one month because my liver couldn't take the drug I guess it was too strong at first, but after going on a healthy high-fat diet of eating salmon, avocado, etc. My liver was fine and I got back on Accutane. Also, I did notice my hair was falling out a lot more and got thinner :( but having clear skin is totally worth it Lol. These were the only bad side effects I experienced tbh. 2 years later and my skin is stillll clear and going strong! I am so happy! I have this confidence now that I never had before tbh. I realized that I shouldn't care what people think even if my acne does return. Now I only get like tiny pimples once a month if I eat too unhealthy or because of my period, which I don't mind. If you are scared of going on Accutane and are reading through reviews and watching videos before you take the plunge please take my advice and go for it!! I survived and so will you!. You have nothing to lose even if it does not work for you. THANK YOU ACCUTANE, I LOVE YOU! <3 LOL

Btw, I was on 40mg once a day for 6 months

Very strong drug, but does the job!!!
Reviewed on May 18, 2016

I have just finished my first month on accutane. The symptoms I have had include: fatigue (like seriously exhausted ALL the time!!), some nausea, a little grouchy (due to fatigue I think), dry lips, dry nose, dry skin, random rashes that pop up and go away overnight after moisturising, sensitivity to the sun, dry scalp, little head aches here and there, a bit of an achy body and if I don't drink enough water my chest hurts due to dehydration. But all of these effects are so small. I travelled to London from Australia on this drug and got a blood nose, not sure if from the plane or the drug, probably the drug lol. But my skin is amazing!!!!!!!! I had an initial break out that was 2 giant pimples and after that my skin just got clearer and clearer. I've only been on the drug a month and I've gone from 30 pimples to 2. I still have redness and scarring but I am feeling positive in time they will go also. If you are unsure whether or not to go on this drug, just do it! I didn't want to take it because I was scared off from everyone's negativity towards it, but really the positives outweigh the negatives. It is a very strong drug-yes, but you are only on it for 3-6 months and then you are free from acne!! 3-6 months of dry skin and feeling weird with an end result of clear skin is much better then never ending depression because of acne. Take the risk, take accutane, but listen to your body, if the drug is too strong for you-stop. but give it a go I'm telling you it works! xxxxxxxxxxxxx

Accutane two months in
Reviewed on May 15, 2016

Hi, I've just started on Accutane in April I started my first month on 20mg and now I've got up too 40mg not really seen much of a difference if anything my skin has more spots and bumps under my skin :( and I'm suffering from dry lips and inside of my nose is dry too. I hope I see an improvement in my skin after these 6 months and the spots that have came out now will they stay till the end because I can't take any more bumps on my skin? I've been using clinque anti blemish moisturiser it's brill for the dry patches and cetaphil cleanser as its gentle on my face and so my skin doesn't flake too much and blistex for my lips it really does help.. If there is anymore tips to help me along this Accutane journey please let me know. And another question I take my tablets at ten clock every night but sometimes I'm ten or 15 minutes late taking them but I read you have to take them on time will it affect my treatment if I'm late by 15 minutes. Many thanks Melissa

Reviewed on April 28, 2016

Was on accutane 3 times! all the right amount of doses, but every time i got off the pill, my acne would come back worse! some people don't get it back, but i wasted so much money. what a scam.

by Gladiatoro on 09/04/2016 20:52
Eliminate dairy , sugar from your diet .
by Lover of life on 11/18/2016 22:04
Have u tried lessening your dose of the pill? I changed pills, I was on a very very low dose whilst taking accutane and now I'm completely off it and no break out :)
Why did I wait so long?
Reviewed on April 25, 2016

I am a 30-year old female who has had bad cystic acne for well over 15 years. I thought Accutane was a last resort for only the worst cases, and I only had it on my chin. I was fed up with trying everything and went to like my 5th derm. She talked about Isotretinoin and I was on board! It took a little getting used to to be seen monthly and filling out the stuff online through iPledge. The first month was kind of bad getting used to the chapped lips (use Aquaphor) and very sensitive skin to the sun (ALWAYS apply sun screen and avoid too much time in the sun). My derm advised me to not drink and I probably did too much towards the end and I would often get sick, so be easy on your liver! By months 2-5 I was loving the results and how non-oily my skin and hair was. I finished after 6 months and I could not be happier and I wonder why I didn't do this 10 years ago and save the heartache over the years. Plus in most cases, you only need to do this once. Be patient, follow your derm's instructions, and do it.

Love it! Week 6 and a HUGE HUGE difference!
Reviewed on April 19, 2016

Just fantastic.

im on 60mg a day for 20weeks. Currently on week 6. Amazing difference!

Side effects so far;

Excessive heavy nosebleeds (slowing now)

Dry skin/rashes (on my arms weirdly)

Mega dry lips (Highly recommend 1% Hydrocortisone cream for stings and rashes- Miracle when you're desperate!)

Dry itchy scalp

Moody/anxiety- a little between weeks 3-4 (now ok)

Had initial flare up of spots on week two, lasted around 10 days, now literally haven't has a new spot since! My skin seems to be peeling like a snake, be on guard with a good moisturiser, tons of lip balm and Vaseline. Stick it up your nose before you go to sleep, gross yes, but you'll thank me for that advice! Any form of Lippy or lip-gloss makes mine ten times worse, so I going with practical over pretty for 20 weeks.

Ive had terrible skin since I was 15, im now 31. I battled to get this med, and it comes with more warnings than an explosive ship. But its SO SO SO WORTH IT!!!!! Week 6, my skin is already better than its looked in my WHOLE adult life!

I can deal with the dry skin etc, the moodiness, a bleeding nose, and scratching my head all day long like I have nits, because my skin is already dramatically different!!! I cant wait to see what I look like by September!

SO seriously, the side effects are a little unpleasant. But isn't having acne day in day out more unpleasant?! I think so. My confidence has been rock bottom for so long. Im always wearing make up. But now im so nearly at the stage by wk6 of going make up free!!!!!!!! Mega life win that will be!

Just a word of advise- DONT try and squeeze spots once you've got going with this medication. Literally all they skin comes off around it and you are left with a huge red patch if red raw skin. Especially around my nose I found, literally it make the skin lift off under pressure. Just leave the spot, it will be gone tomorrow!They vanish the night!

Go for it, you wont regret it!! ( I ignore all the ' this ruined my life reviews'). Make your own mind up. The side effects are gritty, but I cant say living with acne has been much fun so i'll take this one!

Don't delay trying this
Reviewed on April 19, 2016

Best thing to happen to me EVER

Prior to this drug: depression, hated my skin. Avoided all social interaction (as much as I could). Held back on relationships. Didn't bother sitting in certain lighting. Didn't go swimming, sauna, gym etc as I didn't want to be seen without make up. Didn't even open my front door as I couldn't handle the acne on my face.

Accutane period- 7 to 9 odd months of Accutane. I would say it got worse before it got better. This was last resort for me but I was at the end of my tether and NEEDED relief as the acne was cystic, painful, red and unfortunately leaving me with A LOT of scars :(

First few months was hard. Spots kept appearing. Skin hurt.

Month 4-5 turning point in my skin. Clearer, better, brighter complexion. Friends and family noticed the difference and commented on how great it was.

Month 6-9 up and down good and bad skin days. More good than bad. Towards he end it was great. Skin improved and improved even some of the scars filled up. LOVED the drug.

Side effects: dry hair. Dry eyes. That's it nothing else

Positive side effects- have my confidence back. I'm a new person. I can go out with my friends now. I don't hold back in reltionships. I DO have a lot of scarring but I literally do not care (sometimes) as I have been through the sh*t and back with my skin. I am no longer depressed!

One year on; 2016- I do get the odd spots here and there. The acne has DRAMATICALLY reduced. It is not acne anymore it is a few spots mostly around my period. No biggie. I no longer get depressed about this life goes on!

Scars - It does bother me. I have become great at concealing my scars with makeup. You can see them but only if your at a 40 cm distance from my face. So not bad. I will be getting treatment in the near future around 1.5-2 year time.

Bottom line: try the drug. It is close to a miracle. Your depression days will be gone and you can finally feel at peace with your face.


There IS light at the end of the tunnel (cliche but true)