Page 5 of Accutane (isotretinoin) reviews
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Isotretinoin in 10-mg, 20-mg and 40-mg soft gelatin capsules.
Beeswax, butylated hydroxyanisole, edetate disodium, hydrogenated Soybean oil">soybean oil flakes, hydrogenated vegetable oil, and Soybean oil">soybean oil. Gelatin capsules contain glycerin and parabens (methyl and propyl), with the following dye systems: 10 mg - iron oxide (red) and titanium dioxide; 20 mg - FD&C Red No. 3, FD&C Blue No. 1, and titanium dioxide; 40 mg - FD&C Yellow No. 6, D&C Yellow No. 10, and titanium dioxide.
Items marked with red have tested a 3 or above (out of 5) in comedogenic (pore-clogging) testing.
The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.
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After having perfect skin as a teenager, I was mortified when I developed very red acne at 20. 4 years have gone by and I tried everything, natural remedies, diet, ALL over the counter acne options and nothing worked.
Accutane was my last option, and one which I was very hesitant to try as I was concerned about the possible side effects. But I wish I had tried this years ago, I could have avoided so much social anxiety, embarrassment and tears!! I have only been on this for a month, 20mg once a day but I notice a difference after the first week. I did not experience any acne flare up, as I started by taking it every second day for the first week to ease my body in to it and I think the lower dose has been more gentle but still effective. Around the 2 week mark I had minimal sensitivity and slight dryness, but nothing that couldn't be combatted by lots of moisturiser - and it was back to normal after 2 days. The last 2 weeks I have had dry lips, but again a small and manageable side effect compared to having acne! I usually would have multiple pimples popping up every day, but since starting it I would maybe have one new pimple once a week..and this week none at all. Looking in the mirror today I have redness from previous acne, but not one single active pimple..the first time I can say this in 4 years! If you were like me and hesitant, I urge you to try it and talk to your dermatologist about starting on a lower dose to see how your body reacts to it. This has absolutely changed my life, I will now be able to go out with no makeup and not feel like a monster!!! Couldn't be happier with the results :)
I was prescribed Accutane in 2012. I was on 20 mg for the first month and then 40 mg for the next five months. While on the medication, I experienced moderate joint pain, excessive sweating, body odor changes, subtle digestive changes, intermittent episodes of depersonalization, fatigue (mentally), decrease in libido, skin dyness, and eczema.
The worst part of this medication is what persisted AFTER treatment. Although many of the minor side effects subsided, some became worse and/or persisted in the subsequent months. I still get eczema flare-ups to this day. My subtle digestive changes became more serious AND chronic several months after treatment. They still plague me. Joint wise, I have difficulty sitting in certain positions for extended periods of time, which was NOT an issue before Accutane. Lastly and most problematic, my mental health has tanked. I live in a perpetual state of brain fog. I developed a stutter, my mental processing became slower, I was diagnosed with ADHD, and I generally started to feel FLAT. I do not experience emotions like I once did. This makes it hard for me to enjoy hobbies I used to, yet I do not *feel* "sad" or "down" in any way.
Worse yet, ALL of the symptoms I experience can be traced back to a journal article or an internal memo published (but previously withheld) by Roche. I was led to believe any serious side effects were rare and/or reversible. This is simply not the case. Users of this drug should wait several months to a year before determining if their treatment was worth it. As I explained, many of my Accutane-induced issues intensified in the months following cessation. Scary.
I was on Accutane for about 8 months, from 2013-2014. Like many others, I had a terrible initial breakout that pushed a bunch of gunk to the surface of my face over the span of 2-3 weeks. I would wake up in the morning, and my breakouts would look completely different from the night before, because of the rapid rate at which Accutane was working. After the first three weeks, the breakouts slowed, and I started dealing with bigger, deeper cysts that would take about from a couple weeks to a month to go away. At some point, my derm put me on bactrim to help with the cysts that were still lingering.
Once my course was over, my skin was pretty close to perfect. I had no more oil, no more breakouts - good times! My skin stayed clear for about three months, and after that it gradually began reverting to its previous state. At the time of this review, it's been about two years since my accutane course... my skin is super-oily and I have about 5-10 cystic types and 10-20 comedonal pimples on my face at any given time.
Accutane did have some positives for me. It managed to clear my back for the most part, and I'm still at the point where I don't really need to worry about bacne. My facial breakouts are also not as bad as they were pre-accutane.
Unfortunately... given how much the course cost me, how much I had to put up with over 8 months (eczema, constant dryness and itchiness, headaches, flushing, etc), and how quickly my skin reverted back to being oily and breakout-prone, I'd say my first round of accutane was a bust. I'm still open to going on a second course, but not anytime soon.
Ok I know everyone is different, but I was apprehensive to start accutane due to all of the horrific possible side effects and "scare stories". I am in the uk, and paid to see a private dermatologist -pricey! But this can be done free of charge through the nhs too. It is honestly the best thing I have ever done. When I say no side effects; I literally mean 0! To the point where my consultant didn't think my body was absorbing it. I was on 60mg per day and if I'd have weighed more I'd have been put up to 80mg because it wasn't giving me any bad reactions at all. I didn't even get the dry skin! Even so; I was also using topical isotretnoin too. My skin has cleared up AMAZINGLY!
I'm not saying that everyone will get away with side effects Scott free, but what's dry skin for a few months if the end outcome you are free of the crippling acne you've been so desperately trying to fight!? If side effects are bad you can discontinue the medication! But unless your dr says that you have conditions which would make you unsuitable to take it, please give it a go.
My life has changed. I don't want to hide every day. And I can roll out of bed and go to work ;) no more hours of slapping on makeup! Haha
I can't reccomend this highly enough!! Accutane cured my persistent acne that was around for years. I'm currently 18 and have had acne since I was in 7th grade. It was causing scarring, making me insecure, and even at points depression because everything I did wouldn't get rid of it. Finally, after countless topicals and different pills from the dermo, he convinced me to try accutane. I knew friends that had amazing results, but was simply scared of the blood tests because I hate needles! However, this was the best choice I ever made for my acne. I'm now 6 months post accutane and have amazing skin. I also now eat a plan based diet (vegan) and my skin is glowing. There are many unknowns with this drug and it is intense, but I figured it was better than constantly being on different pills trying to find one that worked. I've had no lasting side effects. People that struggle with acne should for sure try this. My 6 month course was all I needed to clear my skin.
This is by far the worst acne drug I've taken. I think I most likely had an allergic reaction to the medication. I ended up vomiting 6+ times in less than 4 hrs. I went to the ER and they tried to give me medication to stop the reaction, and really strong nausea meds that are typically given to chemo patients... I still couldn't hold down anything, including water. I started having breathing problems and they ended up having to give me a steroid shot so I wouldn't go into anaphylactic shock. However, this is an extreme case, and many people have had success with accutane so I'll give it 2 stars. Just... Proceed with caution
I have been taking Roaccutane for 3 months now and it has certainly helped my acne significantly - mine is hormonally related (started in my 30's after coming off the pill) and can give nasty cysts on my neck and jaw area but I have had none since starting. I am in my mid 40's (female) and also have low progesterone - handled with non-synthetic progesterone and hypothyroidism treated with Novothyral . Each work brilliantly in their own right.
However, I have, since starting Roaccutane. gained 4 - 5 kilos (already) - this is probably down to the fact that my digestive system does not seem to be working very well (pellet like stool and not very regular). However, this frustrates me. I am doing as much exercise (and the same type) as before I started. I follow a pretty strict food regime because of my slow metabolism (5/2 or 4/3 - more the latter) although on my days off, i do enjoya little wine (is this the culprit?). Can someone please advise whether this is normal? I don't want to hear that I am 'eating more', 'eating the wrong things', doing less exercise - as this is not the case. Nothing in my diet or regime has changed and I was happily around 65 kgs for years (I am 1.75)
Weight gain is not stipulated anywhere as a side-effect.....but it certainly is and should be. I just hope when I've finished my 5 month course that I will not be 10 kgs heavier!! - then I'm really not sure it's worth taking the Roaccutane, as my skin was only moderately bad when I started.
Any tips on what to do?
I have just finished my 5 months of Accutane and feel I owe it to acne sufferers everywhere and Acne.org to say that please, just give Accutane a go. I have never been more confident in myself as Accutane has drastically cleared up my skin to the point it is absolutely unnoticeable i even had acne. I am back to being me again, and i know you can feel the same. The worst that could happen would be that you don't like the side effects enough to stop taking the medication. For me it's a life changing medication with only positive results. Please don't listen to people talking badly of the drug as if your acne has you feeling low, it is a miracle cure.
And remember no one looks at you the way you do. People see the bigger picture - not just your skin. Sure they will notice you have acne, but anyone who has not suffered themselves would not see it as disgusting, they will see a bit of redness. And the people who have suffered will only sympathize with your situation. And i mean this in the nicest possible way but no one cares about your apperance - they care about theirs much like you only care about your own. So smile, live through it, and trust me. Try accutane.
All the best, Ben
I went on Accutane about a year ago and I had moderate to severe acne before starting my treatment. I also had moderate acne on my back chest and shoulders. I took a generic isotretinoin capsule once a day of I think 400 mg (maybe I can't really remember) for 6 months. It was quite a pain to start, I'm female and my doctor required I take birth control during the entire course of treatment even though I was abstinent the entire time. I had to get a hormone implant called nexplanon a month before I could start the treatment and since I might have to have my wisdom teeth out while I was taking it I had to do that too before I could start. But after all that it did work really well, my acne was completely gone by the time I finished the 6 months. My skin was very dry and I did have a few side effects, I had dry skin, nose and eyes for almost the entire 6 months plus a few months after I stopped taking it. I did not have any severe side effects and had no complications.
Now almost a year after taking the drug, I still get pimples occationally but it's very mild, I still have some minimal scarring from before I took the drug but to my knowledge it was not supposed to fix that at all just prevent any further scarring. The acne on my shoulders, chest and back is completely gone and has not come back at all.
I would recommend this drug, even though it was a bit of a hassle to start and had some scary possible side effects, my acne is almost completely gone and I'm very happy with my skin. I wish you luck if you have acne!
I was so excited to try this after 30 years with acne. I've never had any side effect to any medication and never been on antidepressants or had mental health issues. From the reviews I read I got the impression most people were fine on it, that the main problem was that it might not work, and that a few people who had bad effects had caused it to be prescribed more carefully than was maybe helpful for acne sufferers. I was started on only 20mg and told that would be put up to 40 and 60. By about day 2 I noticed my thoughts were harder to stop than normal, eg I would find it hard to switch off at night, and I woke up from vivid dreams (thoughts still persistently going on in the background) and found it hard to get back to sleep. I had read about this from other reviews who just persisted with treatment so thought that was to be expected and carried on. After about a week I had hardly any dryness on that dose but could tell that my skin was becoming less acne prone - it just felt un-itchy and after suffering from acne for as long as I have I can generally feel when my skin is in a state where I'm liable to break out or not, and the isotretinoin was obviously doing its job, but I kept bursting into tears. By day 9, my skin was clear, but I was in hell. I could only see the bad things about my life, which were blown out of all proportion to a psychotic degree, I was constantly crying, there was no hope, I didn't see anything positive in life or feel the same about my family, and the back of my brain felt like it was coated with tar. I was missing sleep and had lost my appetite. The thought of raising the dose even higher and being on it for months more was unthinkable. There seemed to be no guarantees that this mental change would not be permanent to some degree (I could find studies that showed depression and brain changes after taking it, but none that showed the depression and brain changes as having then gone away after say a few months of stopping treatment, which I would have expected the drug companies might do if it was possible) and the two people I know who have taken accutane don't get spots but are miserable - one is constantly having headaches and is just generally unhealthy and the other is depressed. So I stopped and thankfully the stuff is out of my system (6 weeks ago). I guess we're all different and you can't tell what your response will be.