Page 4 of Isotretinoin (Accutane) reviews

3.9/5 - 1860 reviews
5 star
697 reviews
4 star
659 reviews
3 star
269 reviews
2 star
132 reviews
1 star
103 reviews


Active Ingredients:
Isotretinoin in 10-mg, 20-mg and 40-mg soft gelatin capsules.

Inactive Ingredients:
Beeswax, butylated hydroxyanisole, edetate disodium, hydrogenated Soybean oil">soybean oil flakes, hydrogenated vegetable oil, and Soybean oil">soybean oil. Gelatin capsules contain glycerin and parabens (methyl and propyl), with the following dye systems: 10 mg - iron oxide (red) and titanium dioxide; 20 mg - FD&C Red No. 3, FD&C Blue No. 1, and titanium dioxide; 40 mg - FD&C Yellow No. 6, D&C Yellow No. 10, and titanium dioxide.

Items marked with red have tested a 3 or above (out of 5) in comedogenic (pore-clogging) testing.

The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.

Where to buy is not associated with this product. All proceeds from links go toward maintenance.

[The prices listed above may change at any time and in some cases do not include shipping.]

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Made me lose hope
Reviewed on January 12, 2014

So I tried A LOT of different oral anti-biotics and many different topical creams for my acne and nothing was working. I have moderate inflammatory acne and I told my dermatologist I would take anything at this point to get rid of it. She told me that Accutane is my best bet so of course I agreed. I'm only 14 and my mom was very unsure but she allowed me because she thought I wouldn't have to see the dermatologist ever again after accutane. Well, she was wrong. The side effects were awful. I had joint pain, headaches, and my lips were so chapped that people were asking me how I had crazy chapped lips in the summer.. By my last month (month 5 or 6), I was clear and all i had left were scars but that didn't last long. I do live a healthy lifestyle and work out at least 4 times a week and I have to say I do everything in power everyday to try to get rid of these nasty pimples on my forehead and they don't budge no matter what I do. My acne came back harder than I've ever had it. I have bigger cysts all over my forehead and pimples in places I've never had them in before. I wanted to get clear before my birthday in March but clearly that's not possible anymore.. Right now I'm on no pills but do use Acanya in the morning and Atralin at night, which don't work for me anymore. Seeing my dermatologist at the end of this month, praying there's something out there for me that'll actually clear my skin and keep it clear. I've been starting a dairy-free, wheat-free diet with water as my only drinking option and no junkfood. I've tried everything and I'm starting to think I'm going to have acne forever.

Clears up skin but side effects can be v. severe
Reviewed on January 12, 2014

I went on Oratane (Accutane) for my stubborn, moderate acne. It cleared up my skin in 3 months (with an occasional pimple) and my skin's redness faded. Apart from the usual side effects, Accutane caused me to have suicidal/irrational thoughts and (being a sprinter this was awful) I was unable to exercise because my joints where so sore. I have been off it for a week and I feel much better. So, in conclusion, Accutane clears your skin up but you just have to think about if the side effects are worth it. Oh and I suggest going on Accutane only if you have tried every other method.

it works, but be patient and understand side effects.
Reviewed on January 10, 2014

My son did two courses of treatment in high school. About a year after the first course concluded acne had returned, though on a smaller scale and it was not responding to other treatments. My son actually asked to go on another dose, despite all the unpleasant side effects.

The most significant, and scary, side effect he experienced was depression and anxiety which was subtle but which I definitely believe was a result of the Accutane. He actually experienced fairly marked anxiety for a couple of months following the second course of treatment. Do not underestimate the emotional side effects. Our dermatologist had ever only had a couple patents with those side effects, but I believe it is because the question they ask is are you depressed or suicidal. My sons experience was much more subtle and in the case of depression it was recognized by me, not him.

My son also experienced the extreme dryness. And he got a pretty bad sunburn too since he didn't adequately apply sunscreen as instructed by Dr. and mom.

Some of the doses listed in other reviews seem really low and the course of treatment a bit contrary to how our doctor explained it worked. I would not allow a GP to prescribe. In fact our family doctor refused to, referring us to a dermatologist due to the nature of the product and the sever side effects.

My husband also did two coursed of the treatment in his early twenties and not nearly 50 still struggles with breakouts, so it's not a total cure, but during the difficult teen and early 20s can definitely he'll boost self esteem.

My progress on Claravis(Accutane)
Reviewed on January 10, 2014

I am an 18 year old girl who has had acne since the fourth grade. I have been on countless medications to try and help my skin; Tetracycline, Minocycline, Doxycycline, and Ortho Tri cycline (birth control). None of these helped. I have used Proactive (twice) that didn't help in the least bit, so my last resort was Accutane. I was very nervous about it, having done my research on it, I wasn't sure if I wanted to. Well, let me tell you, I am so glad I did. I am only on my second month, and my skin is so smooth. Before, I had cysts and nodules all along my jaw, my neck, my chest, my upper back, and my cheeks. Now, they're flat and fading. I don't have any on my face, my chest is now drying out, and my neck looks better. The first month, I experienced breaking out on my neck, the cysts were huge! They hurt, and it was just embarrassing. I wore scarves for 2 weeks straight to hide them. The area around my lips broke out as well, they were not large and it only lasted about a week (short compared to my other break outs). I am drying out, not as bad as I thought. I was on 40mg for the first month, now I am on 60mg for my second. side effects I am having include dry skin and lips, not bad at all, cured by moisturizer and Vaseline chap stick. I am thirsty and hungry (more than usual) but thirst isn't severe, I don't notice it unless I think about it. I take my medicine with food, yet it makes me hungry and once I eat, the smallest bite will fill me up. I wake up with bloody noses, not ones to bother me, they're just like scabs or clots, which sounds disgusting but that's the only way I can put it. muscle spasms. this one is actually funny to me, because I have never had these. my legs twitch sometimes or my thumb as well. small, quick movements that feel funny. my contacts are starting to stick to my eyes, making things blurry, so I wear glasses more. my skin isn't oily AT ALL. I would normally use my oil blotting sheets about 3+ times a day and now I never need them. saying this, my hair isn't oily either. I would have to wash it EVERY NIGHT..and now I can go a week or so without doing so (I wash my body don't worry) but I don't have to worry about waking up the next day with greasy hair. I itch too, since my skin is drying out. mostly around my elbows and the top of my hands. when my cysts were drying out, they itched as well, it was uncomfortable. I haven't experienced any thoughts of suicide, depression, or severe side effects like some people do, or what the major concerns are. I get blood work done every month, as well as a pregnancy test, you have to answer questions from the iPledge website before filling the medicine, it's easy, but annoying. I feel pretty lucky with what I'm experiencing, slight dryness. this is definitely going to be something that will change my life. I am able to go out in public feeling confident about my skin. I used to always look down or not look people in the eye, but now I can. I am 100% happy with my skin now, and I still have 4 months to go! :) HIGHLY RECOMMENDED and I really, really wish I had started sooner.

Wish I had started earlier!
Reviewed on January 7, 2014

I'm only just starting my 4th month, however my skin has already improved. I'm trying to remember what my skin reacted like during the first month - and I can't remember having any major breakout like some. Now I produce no oil on my face, I still have the occasional pimple, but just on my chin area and a few on the cheeks. It has eliminated the amount of cystic acne I used to get. I still have scarring, but hopefully that will improve over time. Skin tone in general though is a HUGE improvement. I used to have very bumby skin mainly from little white/black heads everywhere... so even though my acne wasn't severe I was devastated by how my skin tone looked overall. As far as side effects go - I have lost weight- about 8 pounds so far (weight 118 now). I have been more achy, occasional night sweats, maybe slightly more tired. No major side effects like some people have posted about thank goodness. I like many of you was scared to start but I think once you get to the point where your skin is making you feel self-conscious it is worth trying Accutane. Life is very precious and I'm happy I can start enjoying my life more now than if I had waited to try Accutane later in life. I should have started this a year ago :(

Accutane - the most effective treatment I've tried but not a miracle cure. Weigh up the pros and cons carefully.
Reviewed on January 5, 2014

My acne wasn't the most severe case ever but it was persistent; 10 years of back and body acne. Various other treatments failed so I decided to give Accutane a go.

I'm a big guy so my dose was large; I started at 20mg worked up to 100mg, my total course length was 34 weeks and a cumulative dosage of about 14000mg. If you don't know what cumulative dose or total dose to body weight ratio is about I suggest you research Accutane further before taking it.

Initially side-effects were minimal but as the course wore on I did start to struggle with dry lips, dry eyes, painful joints and a general feeling of being unwell. Towards the very end my blood work wasn't ideal (lipids) and I felt my mood was bad.

It did clear my skin up the longer the course went on but it was a slow process. I went from having multiple large cysts and nodules on my back to almost none.

Unfortunately because of the side effects above and my already large total dose I had to get off it before my skin was 100% clear. As a result I am now getting a (milder) return of my acne after 8 months off. I have now started another course which is going to be a low dose over a longer time frame.

I would cautiously recommended it to people with severe acne or moderate persistent acne that is scarring.

This is a powerful drug and you need to treat it AND your body with respect while you are on it. Most people will only get the milder (but still sucky) side-effects that I experienced, others may get more serious ones. Research and weigh up the risks carefully.

definitely worth it!
Reviewed on January 4, 2014

i started going to the dermatologist for acne when i was in 8th grade. I tried everything, over the counter things first in 7th grade and tried things like minocycline, bactrim, and a few other pills and lots of topicals. finally, halfway through 10th grade i started accutane. I took 40mg for about 9 months, and just finished it a few weeks ago.this is the first pill to ever clear up the acne on my back. my skin is about perfect now! while taking the pill i got only a few breakouts the whole time and they went away in just a couple of days.

After being off of it for a few weeks, I do have a few very small pimples. But they gave me Differin and when i put it on the acne is gone the next day! I did have a few side effects like high cholesterol which was kind of a hassle, but overall it was completely worth it. This pill changed my life. I had months of always having to have a chapstick with me, not being able to lay flat on my back cause it hurt, and taking fish oil pills, but it was totally worth it to me. i am so thankful for this medication!

Reviewed on January 3, 2014

so ive been on Accutane for 3 months and im about to start my 4th month. I really haven't seen much improvement in my skin besides the redness going down. I have pretty bad acne (cheeks, forehead, and sometimes chin). I was on many medications for my acne and none have worked. Many people I have talked to have said that between the 3rd and 4th month is when I will see big improvement. Idk if the are just saying that to give me hope or if it will clear in the 4th moth. I hope it will. to speed up the process im going to start the regiment. I have heard amazing reviews so hopefully this will do the trick:) so far Accutane not really working :( but should start soon it just take awhile!

Reviewed on December 27, 2013


Hello all, Merry Christmas for starters.. I am currently sitting here feeling quite dismal as I have come to conclusions Roaccutane is really starting to take a toll on me. A little low-down on who I am I'm male and 18 years old I'm taking one 20mg tablet after dinner each day and have been on it roughly two month's or so now. I have had moderately bad acne or just pimples what ever you want to call it for a good three years now. I still believe myself to be a strong person as I've never really let them win but roaccutane I'm finding hard to fight the fire. I've been having really bad anxiety and social problems? Roaccutane is making me feel awkward around people I get into this zone where I think myself to be being really awkward and its a really uncomfortable feeling which I just want to escape and not be there any more. I'm going on a trip with friends over new years in about 5 days and honestly im dreading it because of these horrible feelings I've been getting.. Its a mixture of anxiety and awkwardness.

I'm wondering if anybody else gets these feelings and actually believes like myself Roaccutane is ruining my social skills and potentially the rest of my life?

If there wasn't light at the end of the tunnel which is basically factual i would never recommend especially to close friends or family members this drug as is it really potent and even a strong person i see myself to be is really struggling.

I would love to hear peoples responds and would be over the moon if other people are experiencing this on the drug to so I don't think I'm a complete psychopath.

If anybody else is experiencing these horrible withdrawals I just want to say remember there is light at the end of the tunnel and to be strong. Always keep your mind positive and hang over positive people. Exercise and lying in the sun, hanging around younger siblings and pets always helps and i find to be great.

I wish everyone a happy new years and a safe Christmas.

All the best

Currently using 40 mg Isotrentinoin
Reviewed on December 21, 2013

I just started using this product 7 days ago. I have had acne for about 3 years and I've tried practically every treatment available to me. I have tried doxycycline, clindamycin, penicillin, retin A, birth controls, hormone treatments and tons of topical treatments. The doxycycline did work for about 5 months but then it stopped working so I decided to try Accutane as a last resort. So far I've been on it for 7 days and I've noticed improvement, No more cystic acne and a significant decrease in the size of the spots, I still have some redness and spots but not nearly as bad. The acne on my back is completely gone. The dermatologist told me that my acne could get worse for a little while before it gets better but so far there has only been improvement. I really hope that this treatment continues to work and I will update on the progress. So far I haven't had many side effects. I've had a little dryness but not nearly as much as I expected, I just use a little extra moisturizer and Chapstick and I'm fine. It could be because I just started using the product so I'll let you know if it gets worse. The only other side effect is that I bruise really easily! which is strange because I wasn't expecting it. I'm super clumsy and now I have tons of

bruises. The only other downside of Accutane is the blood tests. I have to get a blood test every month, which I'm dreading but so far the Pros significantly outweigh the cons.