Isotretinoin (Accutane) reviews

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Active Ingredients:
Isotretinoin in 10-mg, 20-mg and 40-mg soft gelatin capsules.

Inactive Ingredients:
Beeswax, butylated hydroxyanisole, edetate disodium, hydrogenated Soybean oil">soybean oil flakes, hydrogenated vegetable oil, and Soybean oil">soybean oil. Gelatin capsules contain glycerin and parabens (methyl and propyl), with the following dye systems: 10 mg - iron oxide (red) and titanium dioxide; 20 mg - FD&C Red No. 3, FD&C Blue No. 1, and titanium dioxide; 40 mg - FD&C Yellow No. 6, D&C Yellow No. 10, and titanium dioxide.

Items marked with red have tested a 3 or above (out of 5) in comedogenic (pore-clogging) testing.

The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.

Where to buy is not associated with this product. All proceeds from links go toward maintenance.

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Worked Amazing
Reviewed on August 18, 2014

I started Accutane in February of 2014 and just finished under a month ago on July 24th. I am currently 13 and started when I was 13. 5 years ago my mom went on it and had more side affects than me, she had dry skin everywhere, cracked lips, very irritated skin (the usual.) As for me, i only had dry lips and for a portion of time my chin was always cracking. Otherwise I had no issues. Like I said, i was on it for 5 months. For the first month i was on one 1, 40mg pill a day, the next month i was upped to 2, 30mg pills a day, for a total of 60mg's a day. Iwas on that same dosage for 2 months after that. To simplify that I was on 60mg's a day for 3 months. :). For the last month I went to only 30mg's a day. When I started I was scared of looking anyone in the eye and my face was always oily. I tried 7 topical gels and another set of pills in the past and no luck:(. Accutane was our last resort. My dermatologist wasn't skeptical at all. I trusted him fully and family supported me. I did it and now I'm as happy as i've ever been. I love my skin and am not afraid to wear no makeup in public anymore! I fully recommend Accutane to anyone who needs it.

Beginning round two.
Reviewed on August 16, 2014

I just started round 2 of accutane today. The first round was 6 months of 40 mg / day. I'm a 120 lb, 21 year old female for reference. Those 6 months were the happiest of my life. I've never been so confident or happy in my own skin. It was FLAT and dry and beautiful. My skin is extremely, extremely oily usually; NOT having that constant itchy oily feeling and having my makeup patchy and sliding off was amazing. I got eczema on my arms and thighs and butt and dry lips and my lower back now aches when I do a housekeeping shift at work, but I really don't mind at all for the sake of clearing my severe acne (face and body) and drying out my skin.

My skin is now clear and flat and thanks to Apple cider vinegar the hyper pigmentation is dramatically reduced. I have permanent scarring but I don't mind. Two months after finishing my first round I'm beginning round 2 because the oil came back after two weeks. My dermatologist says once I'm past childbearing years I can go on 10mg

/day for the rest of my life. Until then he's hoping that a second round will keep my oily skin at bay for longer. I have nothing really bad to say about the drug; it was worthwhile to me and the side effects were nothing terrible and it made me happier and more confident than I've ever been in my life!

Reviewed on August 8, 2014


If you’re reading this, you're most likely struggling with acne and on accutane or deciding whether you should go on it or not. Well I’m here to tell you that its an incredibly difficult choice (obviously) but it is so incredibly worth it. Anyways this is going to be long but I’d like to share my story so that I can help others make a choice that can change their life for the better. In the beginning of high school, I would get occasional break outs. Nothing too serious, it didn't bother me that much. Once I hit my junior year of high school, my skin seemed to get so much worse within a matter of months. My first semester of junior year was spent going on pointless antibiotics and topical gels in order to fix my increasing problem. My cheeks had tons of spots, it seemed like no place was spared. While my acne was not the scarring/cystic type, I could not leave home without a face of foundation at least. My skin would bring me to tears, and I didn't like close up eye contact because I felt that it was incredibly noticeable. I always knew about accutane, but I had stayed away from it because of the things I had heard. Once summer began after my junior year, my skin improved a little from the sun exposure. However, I vowed that I would seriously consider accutane my senior year if my skin got worse after the summer. Sure enough, about a month into senior year the condition of my skin began to worsen once again. Now, I was still debating accutane. As many of you know, you cant drink any alcohol while on it and the side effects listed are quite terrifying. As a senior in high school, i wont lie, I went to parties regularly on the weekends and drinking just happened to be a part of my social life. I know it shouldn't have been this way, but that was why it was such a hard decision for me. Basically I decided to forgo parties with friends in order to have the clear skin that I always wanted. SO I began the whole process, the month long wait and the first blood test and whatnot. I began on 30 mg for my first month. Im a 5’7’’ girl and I weigh about 130 lbs. After about two weeks, I noticed that my face wasn't producing as much oil. IT WAS AWESOME. My hair stayed clean for days. It was super great. So I saw small improvement from there on. For my second month and then the rest of my course of 5.5 months, I was on 60 mg/day. I didn't notice a big difference in side effects with the dosage increase. My side effects were manageable- there were only two things that really bothered me (besides not drinking). First of all after like 3 months my eyes were F**KED UP. I would wake up with eye gunk and they would be red all the time. People always thought i was stoned. IT WAS AWFUL… And secondly, my finger tips got extremely dry (weird as hell I know) - but yeah they looked wrinkly and it was so awful. So by the fifth month, my skin hit a new level of clear. It was crazy. It took five months to get there and then I took the pills for two more weeks after that. I was worried about stopping, but its been about half a year and my skin is in the same wonderful condition! The oil returned but the acne didnt. I feel like a brand new person. I want to tell everyone to at least try this drug if you're struggling. Also to any girls- I suggest birth control. I started halfway through my course and I think it has also helped to keep my skin clear. My eyes are still dry sometimes before I fall asleep, but it isn’t horrible. Either way I am willing to put up with it in order to have my acne gone. Please please let me know if you have any questions. This can change your life!

by Ayushi10 on 08/13/2014 15:21
Nyc to know you got rid of acne. I took this medicine for a month then after 2 weeks of break i took it again for another month . I almost got my acne gone bt its been few days since i stopped taking it and i m getting my acne back and i dint had any side effect. So for how long should i take this medication .
by Ayushi10 on 08/13/2014 15:38
Nyc to know you got rid of acne. I took this medicine for a month then after 2 weeks of break i took it again for another month . I almost got my acne gone bt its been few days since i stopped taking it and i m getting my acne back and i dint had any side effect. So for how long should i take this medication .
Reviewed on August 8, 2014

Accutane is a permanent solution for 7 out of 10 people with acne. It is effective, but for some people (like me) acne comes back within 6 months. I did two rounds of Accutane and unfortunately it came back both times although not as severe. I have bad cystic acne that just wont go away for some reason but now I am taking probiotics, using topicals Duac & Tazorac, drinking lots of water & drinking lots of green tea and red tea (antioxidants) & my acne seems to be under control. I don't regret going on it twice, it did clear up for almost a year & it was so nice to get a little break from acne or oily skin lol! THE STRUGGLE!

by weetillie on 08/15/2014 14:35
Hi I am going to the docs today and hope they will give me roac. How is it working for you ? im panicking about the side effects as i always have bad luck xx
Reviewed on August 7, 2014

Last week I began Accutane ... Something I was hoping it would never come down to but unfortunately after 11 years of suffering with constant breakouts I think it is time to do something a little more drastic.

I first started getting breakouts when I was 12. I had just hit puberty and a majority of the kids in my class had a few spots here and there so I didn't make a huge deal out of it (at first anyway). It wasn't until I turned 14 that I really noticed that their was a problem with my skin. My forehead was covered in tiny little red nodules that it eventually made its way to my cheeks and back. I still remember boys in my class asking what was wrong with my face and it making me feel like complete and utter sh**! At this point I started Pro Activ which to be honest helped clear up a few spots here and there but overall burnt the absolute crap out of my face. I have used other products before that contained benzoyl peroxide of the same dosage and never did that happen to my face. I am going to put it down to the harsh beads along with the chemicals in this product that basically turned my skin into a big red inflamed mess. I am not a dermatologist and maybe that product works for some but I feel to avoid further damage to your skin you need to be gentle when it comes to acne. (topical treatments anyway)

By the time I was 15 up until now, I am 23, the breakouts have been pretty inconsistent. They are always there but the nature of the breakouts I find is constantly changing which makes it difficult on my part to combat. I go from crazy hormonal breakouts to chest pimples, back pimples, crazy hairline acne, oily skin etc etc etc, I have used minocycline and others cycline's along with duac, benzac, differin, the contraceptive pill (of all sorts), natural supplements from the chinese doctor, dermalogica (different ranges), ella bache, supermarket brands, exposed skincare, skin doctors t-zone and the list goes on. I see results but I can honestly say my skin never looks that good.

It wasn't until the past year when my acne turned from scattered blackheads and whiteheads, which as ugly as they were they were coverable to an extent, to large painful cystic lumps along my jaw line and neck that I realised that this problem was not going to go away on it's own.

My self esteem is depleted.

I am currently studying to be a personal trainer, slothing handfuls of foundation on my face is a complete waste of time when I will just sweat it all off not to mention my wallet has really taken a beating over the years due to all the product and expensive skin treatments I have forked out for.

I am 23 and I still feel like an insecure 16 year old when it comes to my skin.

My mother always drilled it into my head that Accutane was a dangerous drug (I asked previously in my teens to go on it) and that it would always cause more harm than good.

For me to be on this product was not a decision that I have taken lightly.

I understand the side effects completely and I currently take medication for depression.

I really feel that no special diet, antibiotic, topical treatment or contraceptive pill will clear my skin.

And honestly if you are going to fork out $100's of dollars a year on skincare you would expect your complexion to be flawless?

My self esteem and wallet have had enough!

So here I am typing this review, sipping my peppermint tea with bleeding chapped lips, extremely dry skin around my nose which hurts every time I move it in the slightest and the biggest most painful cystic pimple on my neck I have ever had.

I can only hope this is what people refer to as the initial breakout and that my skin will finally clear.

I will be sure to keep you guys updated.

Wish me luck!

by weetillie on 08/15/2014 14:36
Hi I am going to the docs today and hope they will give me roac. How is it working for you ? im panicking about the side effects as i always have bad luck xx
Half way!
Reviewed on August 6, 2014

Ok, so I'm going into my junior year of high school and my acne had always been a challenge for me. I'm a natural redhead, and my skin is VERY sensitive. Also, most products and acne treatments that I've used I've been allergic too. I also swim every morning and afternoon every day so my skin is always dry. When I took accutane, my dryness and redness on my face was terrible. It was also extremely sensitive. (it actually hurt putting on makeup sometimes) The first month was horrible. My acne got worse and worse and I couldn't even use topical stuff. It's been almost 3 months and I only have 2 pimples on my face (which is absolutely crazy) and none on my chest or back. With all the crazy and terrible side effects that I went through it was way worth it too have a clear face. I would recommend it too anyone and everyone.

Acne-free for the first time in a decade thanks to Accutane
Reviewed on August 3, 2014

I was terrified to try Accutane. However, at the age of 21, I realized my acne wasn't going any where and I was so sick of it. I had constant breakouts, some cystic acne, and EXTREMELY oily skin. I would fill up one of those Clean & Clear oil absorbing sheets with oil from my face every 90 minutes. Accutane completely changed my skin. It took me about 5 months into my treatment to get completely clear. About 2 weeks after taking Accutane the oil disappeared which was very weird at first. The first day that the oil was gone I was attempting to blot my face as it was so routine to me and I was confused as to why no oil was coming off my face. Thankfully, three months off Accutane and I have remained acne and oil free.

However, I did experience some side effects.

Temporary side effects:

Dry lips (manageable with Aquaphor during the day and Aveeno medicated daily moisturizer at night)

Dry skin (Cetaphil moisturizing cream at night)

Flakey, ITCHY scalp (this lasted only about a month and was fixed with Head & Shoulders)

Anal fissures (gross I know, but I experienced fissures while on Accutane and it was pretty painful. It took forever for them to heal, likely due to this medication. I never had fissures before taking Accutane so I'm convinced they were caused by Accutane. Thankfully they have healed since finishing treatment.)

Side effects that still affect me 3 months post Accutane:

Facial redness (my face used to never get red before, now it gets red when I get embarrassed/hot which sucks)

Facial sweating (I've noticed that my face gets visibly sweaty very easily when I get too warm, I didn't experience this before Accutane)

Aging (I feel that I look more aged since taking Accutane, maybe due to the lack of oil production)

Although the side effects are annoying and intimidating, Accutane is definitely worth trying; it changed my life.

Try it
Reviewed on July 25, 2014

I researched everything about isotretinoin before I started taking it. I wanted to weigh the risks and benefits before taking the drug for 5 months. I have had mild to moderate acne since I was 16 and I am now 26. I tried antibiotics, birth control, ACV, chemical peels (which made it worse), even the regime which irritated my sensitive skin too much to keep using. After talking with my dermatologist, we decided that these other things I have tried did not work and he suggested a five month course on accutane.

There is a lot of waiting involved in order to get the prescription. Waiting after the pregnancy test, waiting to get approved, waiting for results. They make you jump through A LOT of hoops if you are a female, but if you are willing to get the necessary tests every month, it is worth it. My dermatologist prescribed me a low dose of 20mg for the first two months then I went on 30 mg. I am currently ending month 4 and am basically spot free. I have a few marks that are still healing but my skin is the smoothest and clearest it has been since I can even remember. I still have one month to go and I am really looking forward to seeing the end result.

My side effects have been very typical. Dry skin, dry lips, sore joints, low energy, and eczema flare ups. All of my side effects have been bearable. Some of the products that I use to combat dryness are cerave moisturizing facial wash, cerave PM moisturizer, aquaphor & lanolin for my lips. For makeup, I used estee lauder double wear foundation and it helped with covering up any redness or unevenness. After the third month I noticed I needed less and less makeup because I didn't have to cover up anymore. I also love E.L.F lip exfoliator. Another positive side effect besides clear skin has been that my hair has been growing very fast. I asked the dermatologist about this and he could not explain it. I only have to wash my hair every few days because of the lack of oil. Your skin will be very sensitive while on accutane. You have to be very careful not to pick your skin because it will not heal as fast as it normally would. It is also important to note that you cannot tan, get a tattoo, or wax while on accutane. I get my eyebrows threaded instead and it works very well without any irritation. I am tan and do not normally burn while in the sun but while on accutane I burn very easily. Also you are not supposed to drink alcohol while on accutane, when I did, I noticed it affected me strongly so I would not recommend it. I tried three different brands, Claravis, Amnesteem, and Absorbica. I would recommend taking Absorbica if you can because it is absorbed the best. The other brands you are supposed to take it with a fatty meal in order to be absorbed. Even though on the label they warn you about depression, It has not affected my mood at all.

There is a lot of scary information out there about accutane, but I wanted to share my experience and hopefully help someone with their decision to try it. I would recommend it to anyone that struggles with their skin.

Best medication for me
Reviewed on July 28, 2014

I had this medication as i was on antibiotics and an facial cream called differin gel. It worked well at first and my face was clear for my school prom. after prom about 3 weeks my acne started to come back, mainly around the T zone, Nose especially. I still had very oily skin and i would keep washing my face every day and night trying to get rid of it, even using toilet paper to remove it sometimes while at school. i went back to the dermatologist and said i had really oily skin i was put onto Accutane. Within a month i started to notice a difference, my skin was producing far less oil and my spots where less pronounced. within about 6 months or less my face was completely clear and oil free. I was so happy and confident! I was sceptical to try this medication because it was offered to be first as the side affects worried me. but they never seamed to have any effect other than dry skin which i knew was going to happen. Taking it was the best decision ever! I recommend it to anyone. I wish id of done it instead of the first treatment.

A miracle drug for severe acne
Reviewed on July 26, 2014

I've been on a generic brand of Accutane for 5 months now. It has been a miracle drug for me. I used to have horrible hormonal acne and nothing else helped. I suffered major depression and withdrew from socializing and never left my house. Ever since I've been taking this drug, my skin looks flawless. No more excessive oily skin or hair. I do have very dry lips and that's the only side effect that I've come across so far. My doctor started me out on 5mg and now I'm up to 30mg. I've heard once a Accutane patients finish their course of their Accutane treatment, the acne can come back. So it doesn't sound like a long term solution. This drug also does have many side effect warnings as do most other prescription drugs. I am aware of the lawsuits which breaks my heart. I'm hoping that the generic form of Accutane is not completely eliminated. Accutane has saved me from a deeper depression and low self esteem. Society can be so cruel that people feel pressured to fix their flaws so they can live a peaceful life.