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Duac Clindamycin (1.2%) and Benzoyl Peroxide (5%) Gel
3.9/5 - 1328 reviews
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Brand: Duac

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Duac Clindamycin (1.2%) and Benzoyl Peroxide (5%) Gel


Active Ingredients:
Clindamycin Phosphate (1.2%) and Benzoyl Peroxide (5%).

Inactive Ingredients:
Carbomer 980, dimethicone 100, disodium lauryl sulfosuccinate, disodium edetate, glycerol, silicon dioxide, poloxamer, purified water, sodium hydroxide.

The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.

Duac Clindamycin (1.2%) and Benzoyl Peroxide (5%) Gel

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Duac Clindamycin (1.2%) and Benzoyl Peroxide (5%) Gel

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Works well for me
Reviewed on July 16, 2014

This is my go to product. Its worked really well but I also follow a schedule or regimen daily which I never skip.

I allpy this at night . First i start by cleansing with Bioderma Sensibo H20, then i apply this gel avoiding eyes and nose. Wait for it

To dry and go to bed. The next morning I clean with bioderma again then apply my sunscreen.

This did work for me. I tried everything else been a mission for 10 years.

For me this is all that works , I also keep my carb intake to a bare minimum.

Didn't really help
Reviewed on June 22, 2014

Was prescribed this a couple of years ago. It dried out the spots but unfortunately also dried the skin so I had to stop using it.

Why does this cost so much?
Reviewed on June 16, 2014

Unfortunately, my health insurance didn't cover this. So I had to pay full price (I don't remember the exact price, it was near $200 I think). It did work better than OTC creams like Clearasil, but not THAT much better. It definitely was not worth the price. I don't know why dermatologists insists on prescribing me things that cost an arm and a leg. It's not realistic to keep that up long term. I don't have that extra amount of money to shell out every month. That's partially why I stopped going to dermatologists. They don't put any effort into finding the root cause (food allergy, hormones, etc...). They look at your face for a few seconds without giving you a chance to ask questions, then tell you to wash with Cetaphil and prescribe a bunch of overpriced creams in rapid succession. Then they resort to Accutane (which didn't work for me btw). Sorry, I shouldn't say all derms, but the long list of ones I went to were all like that and I don't have the money for the trial and error of finding one who is worth it. I would give Duac 3 or 4 stars if it weren't for the price, but I'm strongly against how these companies are overcharging for their products, taking advantage of the emotional anguish of acne sufferers. I would buy Duac again if the price were knocked down to something more reasonable. Benzoyl Peroxide is dirt cheap. Clindamycin is dirt cheap. So why does Duac cost do much when those are the two active ingredients? Heck, I'd even pay $50, but not $200. Dan's Regimen and products are working better than Duac anyway, and much cheaper to boot.

I hate Duac!
Reviewed on June 5, 2014

I started using Duac a few years ago - it really cleared my face (with the help of Differin, too), which was obviously so amazing and gave me such confidence - I loved it. However, after 2 years, my acne came back, worse than ever actually. Duac became ineffective for me (maybe my skin got used to it), but my dermatologist says I should still use it. I absolutely can't stand putting this stuff on my face now - it burns, stays sticky for hours, makes my faces red and patchy and stings. Not to mention bleaches everything it touches. I literally can't handle putting this stuff on my face these days, it just hurts me so badly.

Obviously everybody's skin type is different, so it may clear you forever! I do have really sensitive skin, so maybe it's too strong for me now or something. It's just so heartbreaking to me that for a couple of years I didn't have to wear make up and could walk out of my house with such confidence, feeling great about my clear skin, to now - my skin is really bad and I'm well into my twenties!

by mcmounty5 on 06/06/2014 21:28
You may have become resistant to the antibiotic (clindamycin) in Duac. Pretty common actually. Sad part is, most doctors don't know that you can become antibiotic resistant even to topical skin treatments. Be careful though, you might want a second opinion. Being antibiotic resistant not only means that your Duac wont work, but could also be more serious if your body needed to rely on Clindamycin for some other bacterial infection. If you're going to be on acne medication for a long time you should really look for something without an antibiotic.
by tashadabest on 11/28/2014 14:38
You should try dans regimen on!
Couldn't get on with it
Reviewed on May 21, 2014

I used this gel for about a month and as much as i wish it did help my acne it made it alot worse and left my face very oily! Also when applying the gel it left my face very tight and would usually just rub off anyway!

Worked wonders for awhile
Reviewed on May 8, 2014

When I was first prescribed this medication, within two weeks my moderate acne cleared up. I did find it drying but it was tolerable, as I'd rather have dry skin than acne skin. The only downside I saw this this medication is after about two years of using it, it started to be less effective. I have been told you can try quitting for awhile and starting up again later, but haven't done that yet. It did work wonders for the first two years however.

by kevinx111 on 09/10/2015 22:16
2 weeks really? That' quick
Hideously drying!
Reviewed on May 8, 2014

I'll admit, I only tried this for two days so I can't say whether it works but I really couldn't stand it any longer. This made my face so tight, I could barely move my mouth, it was like it was covered in clingfilm. When you're covered in very painful, cystic acne, the last thing you want is really tight skin. I might give it another go when my acne subsides a little.

by Jordanbell on 06/20/2014 08:44
I had the same and I think it actually took a layer of my skin off but I persevered and after 5 weeks the dry skin disappeared and no more spots - I love the stuff :)
Helped at the beginning
Reviewed on May 5, 2014

Did clear a few spots I had. Seems the bacteria on my skin has grown resistant to it though.

Wish it worked for me
Reviewed on May 4, 2014

I got this from my doctors as it was recommended to me by two people, one a friend and the other someone who was matching my colour foundation at a make up stand in selfridges. But unfortunately it did not work for me, my acne is mild but I have scarring left after a break out that bothers me. So I am aiming to reduce break outs so no new scarring and find away to fade existing scars. I think I used this product correctly. I applied to clean dry skin twice a day before applying moisturiser but I didn't always follow with moisturiser. Maybe it works but in my case it didn't and I have to be honest. I am now venturing into chemical peels now :) gradually and safely. I would recommend as I may work for the majority. I was excited to at least see improvement for blackheads as it indicates but no nothing. The only pro I can express is that it does irritate my skin or dry.

Works Miracles
Reviewed on April 19, 2014

I am in my early 20's and have always had mild acne, unfortunately it became a bit worse after moving to Germany. Going from sunny San Diego to the depths of winter in Berlin drastically changed my skin for the worse. My acne had never been so bad and the climate change made a huge difference. Still living in Berlin, I finally was prescribed Duac and it worked like magic. I saw results in just a few days of using this product. After using Duac for at least a month now, my skin is clearer than ever and my acne scars are not as noticeable. It does have the tendency to dry the skin and cause a little irritation/burning sensation. After using this nearly every night for a month, I have gathered a few tips that work best for me and possibly for others as well.

*A reminder that I do have fairly oily skin so these tips may not work as well for those with dry skin. But I do recommend always moisturizing!


Wait 15-30 minutes after cleansing the skin before applying Duac

After applying Duac, wait 15-30 minutes before applying a moisturizer

(These techniques will help your skin stay moisturized)

The moisturizer (La Roche-Posay Effaclar H) I use is very effective and also helps with mild acne and especially redness/blemishes, it is mainly for those with oily skin and is perfect when using drying skin care products.

Best of luck!