• Allergy: While allergy to benzoyl peroxide is rare, is does sometimes occur. To test for allergy, apply a nickel size amount of benzoyl peroxide to your inner forearm for 2-3 nights. If you experience swelling and/or severe crusting, do not use benzoyl peroxide. If your skin fares well, test on your temple for another 2-3 nights. Again, if you see swelling and/or severe crusting, discontinue use of benzoyl peroxide. If you are unsure or have any doubt, check with your doctor.
  • Less than 1:1000 people experience contact sensitization to benzoyl peroxide over time. Symptoms can be confused as a worsening of the disease but are in fact due to contact sensitization.
  • Benzoyl peroxide has not been studied in pregnant mothers. Consult your physician before using any medication, topical or otherwise, during pregnancy.