Comments on: Acne vaccine in our future?

By: OhSchnap

OhSchnap — Mon, 08 Nov 2010 10:03:45 +0000

I imagine stopping P. acnes in its tracks would do wonders for sufferers with inflammatory issues. I would happily dish out thousands for such a result, regardless of whether I have to card it.

By: k m

k m — Sun, 12 Sep 2010 04:36:10 +0000

please help god…..make my life livable…please

By: peggy

peggy — Sat, 21 Aug 2010 18:45:43 +0000

I wonder if the big pharmaceutical companies actually WANT acne cured or prevented. It’s a multi-BILLION dollar gravy train. Keep us posted, Dan. You give hope to the hopeless.

By: empty inside

empty inside — Sat, 24 Jul 2010 23:19:17 +0000

please, please just release this already i cant live like this any longer!!

By: Jasmine 215

Jasmine 215 — Sun, 18 Apr 2010 07:01:55 +0000

Hi Dan,

It is more than time for an Acne vaccine to be developed, it should have been done 100 years ago!

Too bad they can’t administer this to all children by the age of 10-11 or so, just in time for puberty.

B5 vitamins and Accutane supposedly will freeze the sebaceous glands in their prepubertal state in most children, causing their skin to stay in that condition supposedly. There are bad side effects to Accutane, however, as most people are aware.

So that is why they need a cure and/or prevention with a vaccine.

I read somewhere on the Internet that a group of young men went to a doctor in the 1960s, who then injected them with what sounds like a vaccine for Propriones acne bacterium, and in each case, their severe, disfiguring Acne had cleared and NEVER returned. It sounds like someone pulled it off the market after that though.

Jasmine

By: quorum sensing

quorum sensing — Tue, 23 Feb 2010 05:35:30 +0000

This research is worth funding and I wouldn’t wait for Glaxo. A p.acnes vaccine might solve the entire problem for most people, because it is likely that the related problems of clogged follicles result from quorum sensing by p.acnes bacteria. The bacteria live on the skin, and can harmlessly enter the follicles, but when they sense a quorum they change their behavior and texture. Most likely, they become sticky and block desquamation, trapping dead cells to feed the growing colony, which can then pump out more bacteria to find more follicles. It’s a bit like anthills or termite mounds. If you stop the bacteria, or disrupt their ability to sense a quorum, or take away their ability to change behavior when they have a quorum, then you’ll likely stop the whole cycle. (Other problems, like excess oil causing shiny skin, do require other solutions.) Please post whatever you hear from UCSD (or elsewhere), and maybe smaller biotechs can be encouraged too.

By: poopy

poopy — Thu, 21 Jan 2010 05:05:02 +0000

this would be so awesome!

By: clara

clara — Sat, 12 Dec 2009 08:39:05 +0000

OMFG THIS WOULD BE AWSOME!!! KEEP US UPDATED!!!!! seriously as soon as this comes out (if it does) im SOOO getting it!

By: Milkoholic17

Milkoholic17 — Sun, 29 Nov 2009 09:25:47 +0000

I happen to go to UCSD, so if you need any help at all, I would love to help you Dan!

By: Jim DeSantis

Jim DeSantis — Fri, 27 Nov 2009 18:04:03 +0000

This would be great news for the millions who suffer from acne and spend major dollars on concoctions and medical treatments that do not provide a “cure” only a control mechanism.

Jim

By: Sharpy

Sharpy — Sat, 21 Nov 2009 15:32:13 +0000

Can’t wait to hear more about this!

By: Tom

Tom — Fri, 20 Nov 2009 21:33:20 +0000

Let’s say that a vaccine will successfully eliminate P-acnes bacteria formation, but there is still pore clogging from overproduction of oils or other causes, will the acne related visual symptoms (pimples/cysts) be gone or they are not dependent on P-acnes bacteria?

By: Micheal

Micheal — Fri, 20 Nov 2009 09:38:59 +0000

Wow Great article. I hope that they do go forward with research for this.
This would be huge!

Micheal

By: ^_^

^_^ — Thu, 19 Nov 2009 16:21:02 +0000

thats really cool

i hope it happens

By: Paul

Paul — Thu, 19 Nov 2009 00:12:23 +0000

Go Dan! You are our only hope!